메뉴 건너뛰기




Volumn 57, Issue 6, 2010, Pages 885-892

Ribonucleotide reductase M2 subunit is a novel diagnostic marker and a potential therapeutic target in bladder cancer

Author keywords

Bladder cancer; Gemcitabine; Immunohistochemistry; Ribonucleotide reductase M2 subunit; Urothelial carcinoma

Indexed keywords

RIBONUCLEOTIDE REDUCTASE; RIBONUCLEOTIDE REDUCTASE M2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 78650253325     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2010.03725.x     Document Type: Article
Times cited : (86)

References (26)
  • 1
    • 59249101715 scopus 로고    scopus 로고
    • The global burden of urinary bladder cancer
    • Parkin DM. The global burden of urinary bladder cancer. Scand. J. Urol. Nephrol. Suppl. 2008; 218; 12-20.
    • (2008) Scand. J. Urol. Nephrol. Suppl. , vol.218 , pp. 12-20
    • Parkin, D.M.1
  • 3
    • 0023867072 scopus 로고
    • Natural history and treatment of low and high risk superficial bladder tumors
    • Rubben H, Lutzeyer W, Fischer N, Deutz F, Lagrange W, Giani G. Natural history and treatment of low and high risk superficial bladder tumors. J. Urol. 1988; 139; 283-285.
    • (1988) J. Urol. , vol.139 , pp. 283-285
    • Rubben, H.1    Lutzeyer, W.2    Fischer, N.3    Deutz, F.4    Lagrange, W.5    Giani, G.6
  • 4
    • 77449109234 scopus 로고    scopus 로고
    • Randomized phase III trial on gemcitabine versus mytomicin in recurrent superficial bladder cancer: evaluation of efficacy and tolerance
    • Addeo R, Caraglia M, Bellini S et al. Randomized phase III trial on gemcitabine versus mytomicin in recurrent superficial bladder cancer: evaluation of efficacy and tolerance. J. Clin. Oncol. 2010; 28; 543-548.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 543-548
    • Addeo, R.1    Caraglia, M.2    Bellini, S.3
  • 5
    • 0033857218 scopus 로고    scopus 로고
    • Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study
    • von der Maase H, Hansen SW, Roberts JT et al. Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study. J. Clin. Oncol. 2000; 18; 3068-3077.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 3068-3077
    • von der Maase, H.1    Hansen, S.W.2    Roberts, J.T.3
  • 6
    • 0021908232 scopus 로고
    • Subunit M2 of mammalian ribonucleotide reductase. Characterization of a homogeneous protein isolated from M2- overproducing mouse cells
    • Thelander M, Graslund A, Thelander L. Subunit M2 of mammalian ribonucleotide reductase. Characterization of a homogeneous protein isolated from M2- overproducing mouse cells. J. Biol. Chem. 1985; 260; 2737-2741.
    • (1985) J. Biol. Chem. , vol.260 , pp. 2737-2741
    • Thelander, M.1    Graslund, A.2    Thelander, L.3
  • 7
    • 70149119002 scopus 로고    scopus 로고
    • Clinical pharmacology and pharmacogenetics of gemcitabine
    • Wong A, Soo RA, Yong WP, Innocenti F. Clinical pharmacology and pharmacogenetics of gemcitabine. Drug Metab. Rev. 2009; 41; 77-88.
    • (2009) Drug Metab. Rev. , vol.41 , pp. 77-88
    • Wong, A.1    Soo, R.A.2    Yong, W.P.3    Innocenti, F.4
  • 8
    • 0019819578 scopus 로고
    • Ribonucleotide reductase in cultured mouse lymphoma cells. Cell cycle- dependent variation in the activity of subunit protein M2
    • Eriksson S, Martin DW Jr. Ribonucleotide reductase in cultured mouse lymphoma cells. Cell cycle- dependent variation in the activity of subunit protein M2. J. Biol. Chem. 1981; 256; 9436-9440.
    • (1981) J. Biol. Chem. , vol.256 , pp. 9436-9440
    • Eriksson, S.1    Martin Jr, D.W.2
  • 9
    • 1542742114 scopus 로고    scopus 로고
    • RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine
    • Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine. Oncogene 2004; 23; 1539-1548.
    • (2004) Oncogene , vol.23 , pp. 1539-1548
    • Duxbury, M.S.1    Ito, H.2    Zinner, M.J.3    Ashley, S.W.4    Whang, E.E.5
  • 10
    • 34447503264 scopus 로고    scopus 로고
    • Ribonucleotide reductase subunit M2 mRNA expression in pretreatment biopsies obtained from unresectable pancreatic carcinomas
    • Itoi T, Sofuni A, Fukushima N et al. Ribonucleotide reductase subunit M2 mRNA expression in pretreatment biopsies obtained from unresectable pancreatic carcinomas. J. Gastroenterol. 2007; 42; 389-394.
    • (2007) J. Gastroenterol. , vol.42 , pp. 389-394
    • Itoi, T.1    Sofuni, A.2    Fukushima, N.3
  • 11
    • 33846296549 scopus 로고    scopus 로고
    • RRM2 induces NF- kappaB- dependent MMP- 9 activation and enhances cellular invasiveness
    • Duxbury MS, Whang EE. RRM2 induces NF- kappaB- dependent MMP- 9 activation and enhances cellular invasiveness. Biochem. Biophys. Res. Commun. 2007; 354; 190-196.
    • (2007) Biochem. Biophys. Res. Commun. , vol.354 , pp. 190-196
    • Duxbury, M.S.1    Whang, E.E.2
  • 12
    • 63849188689 scopus 로고    scopus 로고
    • Overexpression of RRM2 decreases thrombspondin- 1 and increases VEGF production in human cancer cells in vitro and in vivo: implication of RRM2 in angiogenesis
    • Zhang K, Hu S, Wu J et al. Overexpression of RRM2 decreases thrombspondin- 1 and increases VEGF production in human cancer cells in vitro and in vivo: implication of RRM2 in angiogenesis. Mol. Cancer 2009; 8; 11.
    • (2009) Mol. Cancer , vol.8 , pp. 11
    • Zhang, K.1    Hu, S.2    Wu, J.3
  • 13
    • 33847417505 scopus 로고    scopus 로고
    • Ribonucleotide reductase subunits M2 and p53R2 are potential biomarkers for metastasis of colon cancer
    • Liu X, Zhou B, Xue L et al. Ribonucleotide reductase subunits M2 and p53R2 are potential biomarkers for metastasis of colon cancer. Clin. Colorectal Cancer 2007; 6; 374-381.
    • (2007) Clin. Colorectal Cancer , vol.6 , pp. 374-381
    • Liu, X.1    Zhou, B.2    Xue, L.3
  • 14
    • 43649096317 scopus 로고    scopus 로고
    • Ribonucleotide reductase subunits M1 and M2 mRNA expression levels and clinical outcome of lung adenocarcinoma patients treated with docetaxel/gemcitabine
    • Souglakos J, Boukovinas I, Taron M et al. Ribonucleotide reductase subunits M1 and M2 mRNA expression levels and clinical outcome of lung adenocarcinoma patients treated with docetaxel/gemcitabine. Br. J. Cancer 2008; 98; 1710-1715.
    • (2008) Br. J. Cancer , vol.98 , pp. 1710-1715
    • Souglakos, J.1    Boukovinas, I.2    Taron, M.3
  • 15
    • 0036373805 scopus 로고    scopus 로고
    • The WHO/ISUP 1998 and WHO 1999 systems for malignancy grading of bladder cancer. Scientific foundation and translation to one another and previous systems
    • Busch C, Algaba F. The WHO/ISUP 1998 and WHO 1999 systems for malignancy grading of bladder cancer. Scientific foundation and translation to one another and previous systems. Virchows Arch. 2002; 441; 105-108.
    • (2002) Virchows Arch. , vol.441 , pp. 105-108
    • Busch, C.1    Algaba, F.2
  • 16
    • 0003809054 scopus 로고    scopus 로고
    • AJCC cancer staging manual
    • 6th edn. Philadelphia, PA: Lippincott- Raven
    • Greene FL, Page DL, Fleming ID et al. AJCC cancer staging manual, 6th edn. Philadelphia, PA: Lippincott- Raven, 2002; 335-337.
    • (2002) , pp. 335-337
    • Greene, F.L.1    Page, D.L.2    Fleming, I.D.3
  • 17
    • 33745212839 scopus 로고    scopus 로고
    • Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target
    • Ito H, Funahashi S, Yamauchi N et al. Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target. Clin. Cancer Res. 2006; 12; 3257-3264.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 3257-3264
    • Ito, H.1    Funahashi, S.2    Yamauchi, N.3
  • 18
    • 0034941337 scopus 로고    scopus 로고
    • Discriminatory immunohistochemical staining of urothelial carcinoma in situ and non- neoplastic urothelium: an analysis of cytokeratin 20, p53, and CD44 antigens
    • McKenney JK, Desai S, Cohen C, Amin MB. Discriminatory immunohistochemical staining of urothelial carcinoma in situ and non- neoplastic urothelium: an analysis of cytokeratin 20, p53, and CD44 antigens. Am. J. Surg. Pathol. 2001; 25; 1074-1078.
    • (2001) Am. J. Surg. Pathol. , vol.25 , pp. 1074-1078
    • McKenney, J.K.1    Desai, S.2    Cohen, C.3    Amin, M.B.4
  • 19
    • 1542344542 scopus 로고    scopus 로고
    • Agarose cell block: innovated technique for the processing of urine cytology for electron microscopy examination
    • Mansy SS. Agarose cell block: innovated technique for the processing of urine cytology for electron microscopy examination. Ultrastruct. Pathol. 2004; 28; 15-21.
    • (2004) Ultrastruct. Pathol. , vol.28 , pp. 15-21
    • Mansy, S.S.1
  • 20
    • 35348813788 scopus 로고    scopus 로고
    • Identification of Toll- like receptor 3 as a potential therapeutic target in clear cell renal cell carcinoma
    • Morikawa T, Sugiyama A, Kume H et al. Identification of Toll- like receptor 3 as a potential therapeutic target in clear cell renal cell carcinoma. Clin. Cancer Res. 2007; 13; 5703-5709.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 5703-5709
    • Morikawa, T.1    Sugiyama, A.2    Kume, H.3
  • 21
    • 0037343146 scopus 로고    scopus 로고
    • Immunohistochemical expression of CK20, p53, and Ki- 67 as objective markers of urothelial dysplasia
    • Mallofre C, Castillo M, Morente V, Sole M. Immunohistochemical expression of CK20, p53, and Ki- 67 as objective markers of urothelial dysplasia. Mod. Pathol. 2003; 16; 187-191.
    • (2003) Mod. Pathol. , vol.16 , pp. 187-191
    • Mallofre, C.1    Castillo, M.2    Morente, V.3    Sole, M.4
  • 22
    • 67349119922 scopus 로고    scopus 로고
    • Evaluation of mRNA by Q- RTPCR and protein expression by AQUA of the M2 subunit of ribonucleotide reductase (RRM2) in human tumors
    • Kolesar J, Huang W, Eickhoff J et al. Evaluation of mRNA by Q- RTPCR and protein expression by AQUA of the M2 subunit of ribonucleotide reductase (RRM2) in human tumors. Cancer Chemother. Pharmacol. 2009; 64; 79-86.
    • (2009) Cancer Chemother. Pharmacol. , vol.64 , pp. 79-86
    • Kolesar, J.1    Huang, W.2    Eickhoff, J.3
  • 23
    • 46449091470 scopus 로고    scopus 로고
    • Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2
    • Yun HJ, Cho YH, Moon Y et al. Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2. Exp. Mol. Med. 2008; 40; 345-353.
    • (2008) Exp. Mol. Med. , vol.40 , pp. 345-353
    • Yun, H.J.1    Cho, Y.H.2    Moon, Y.3
  • 24
    • 19044394312 scopus 로고    scopus 로고
    • Overview of ribonucleotide reductase inhibitors: an appealing target in anti- tumour therapy
    • Cerqueira NM, Pereira S, Fernandes PA, Ramos MJ. Overview of ribonucleotide reductase inhibitors: an appealing target in anti- tumour therapy. Curr. Med. Chem. 2005; 12; 1283-1294.
    • (2005) Curr. Med. Chem. , vol.12 , pp. 1283-1294
    • Cerqueira, N.M.1    Pereira, S.2    Fernandes, P.A.3    Ramos, M.J.4
  • 25
    • 69049105318 scopus 로고    scopus 로고
    • Phase I trial of GTI- 2040, oxaliplatin, and capecitabine in the treatment of advanced metastatic solid tumors: a California Cancer Consortium Study
    • Shibata SI, Doroshow JH, Frankel P et al. Phase I trial of GTI- 2040, oxaliplatin, and capecitabine in the treatment of advanced metastatic solid tumors: a California Cancer Consortium Study. Cancer Chemother. Pharmacol. 2009; 64; 1149-1155.
    • (2009) Cancer Chemother. Pharmacol. , vol.64 , pp. 1149-1155
    • Shibata, S.I.1    Doroshow, J.H.2    Frankel, P.3
  • 26
    • 20144387142 scopus 로고    scopus 로고
    • Intravesical administration of small interfering RNA targeting PLK- 1 successfully prevents the growth of bladder cancer
    • Nogawa M, Yuasa T, Kimura S et al. Intravesical administration of small interfering RNA targeting PLK- 1 successfully prevents the growth of bladder cancer. J. Clin. Invest. 2005; 115; 978-985.
    • (2005) J. Clin. Invest. , vol.115 , pp. 978-985
    • Nogawa, M.1    Yuasa, T.2    Kimura, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.