Androgen- and estrogen-secreting adrenal cancers

Seminars in Oncology

Volumn 37, Issue 6, 2010, Pages 638-648

  Cavlan, Dominic ^a   Bharwani, Nishat ^b   Grossman, Ashley ^c  

^a BARTS HEALTH NHS TRUST   (United Kingdom)

^b Royal Free Hampstead ^*  (United Kingdom)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; BEVACIZUMAB; ERLOTINIB; ESTROGEN; GEFITINIB; MITOTANE;

ADRENAL CANCER; ADRENAL CORTEX CARCINOMA; ANDROGEN RELEASE; ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; DIAGNOSTIC APPROACH ROUTE; DIAGNOSTIC IMAGING; DIFFERENTIAL DIAGNOSIS; DRUG EFFICACY; DRUG RESPONSE; ESTROGEN RELEASE; HUMAN; IMAGE ANALYSIS; METASTASIS; PRIORITY JOURNAL; SYMPTOM;

ADRENAL GLAND NEOPLASMS; ADRENALECTOMY; ADRENOCORTICAL CARCINOMA; ADULT; ALGORITHMS; ANDROGENS; ANTINEOPLASTIC AGENTS, HORMONAL; CHILD; DIAGNOSTIC IMAGING; ESTROGENS; FEMALE; HUMANS; MITOTANE; PROGNOSIS; VIRILISM;

EID: 78650231777     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2010.10.016     Document Type: Article

References (81)

1. T.J. McKenna, and S.K. Cunningham The pathogenesis of adrenal and extra adrenal hyperandrogenism J Steroid Biochem Mol Biol 45 1993 117 121
2. J.S. Gell, B.R. Carr, and H. Sasano Adrenarche results from development of a 3beta-hydroxysteroid dehydrogenase-deficient adrenal reticularis J Clin Endocrinol Metab 83 1998 3695 3701
3. W. Arlt Androgen therapy in women Eur J Endocrinol 154 2006 1 11
4. E.R. Simpson Sources of estrogen and their importance J Steroid Biochem. Mol Biol 86 2003 225 230
5. R.L. Rosenfield Hirsutism N Engl J Med 353 2005 2578 2588
6. A.C. Latronico, and G.P. Chrousos Adrenocortical tumors J Clin Endocrinol Metab 82 1997 1317 1324
7. M.D. Wooten, and D.K. King Adrenal cortical carcinoma Epidemiology and treatment with mitotane and a review of the literature Cancer 72 1993 3145 3155
8. J. Luton, S. Cerdas, and L. Billaud Clinical features of adrenocortical carcinoma, prognostic factors, and the effect of mitotane therapy N Engl J Med 322 1990 1195 1201
9. A. Koschker, M. Fassnacht, S. Hahner, D. Weismann, and B. Allolio Adrenocortical carcinomaimproving patient care by establishing new structures Exp Clin Endocrinol Diabetes 114 2006 45 51
10. B.L. Wajchenberg, M.A. Albergaria Pereira, and B.B. Medonca Adrenocortical carcinoma: clinical and laboratory observations Cancer 88 2000 711 736
11. S. Roman Adrenocortical carcinoma Curr Opin Oncol 18 2006 36 42
12. R.C. Ribeiro, F. Sandrini, and B. Figueiredo An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma Proc Natl Acad Sci U S A 98 2001 9330 9335
13. G. Abiven, J. Coste, and L. Groussin Clinical and biological features in the prognosis of adrenocortical cancer: poor outcome of cortisol-secreting tumors in a series of 202 consecutive patients J Clin Endocrinol Metab 91 2006 2650 2655
14. M.S. Didolkar, R.A. Bescher, E.G. Elias, and R.H. Moore Natural history of adrenal cortical carcinoma: a clinicopathologic study of 42 patients Cancer 47 1981 2153 2161
15. M. Fassnacht, and B. Allolio Clinical management of adrenocortical carcinoma Best Pract Res Clin Endocrinol Metab 23 2009 273 289
16. B. Allolio, and M. Fassnacht Adrenocortical carcinoma: clinical update J Clin Endocrinol Metab 91 2006 2027 2037
17. S. Moreno, G. Montoya, and J. Armstrong Profile and outcome of pure androgen-secreting adrenal tumors in women: experience of 21 cases Surgery 136 2004 1192 1198
18. B.B. Mendonca, A.M. Lucon, and C.A. Menezes Clinical, hormonal and pathological findings in a comparative study of adrenocortical neoplasms in childhood and adulthood J Urol 154 1995 2004 2009
19. R. Sandrini, R.C. Ribeiro, and L. DeLacerda Childhood adrenocortical tumors J Clin Endocrinol Metab 82 1997 2027 2031
20. F. Cordera, C. Grant, J. van Heerden, G. Thompson, and W. Young Androgen-secreting adrenal tumors Surgery 134 2003 874 880
21. T. Imai, J. Tobinaga, and T. Morita-Matsuyama Virilizing adrenocortical adenoma: in vitro steroidogenesis, immunohistochemical studies of steroidogenic enzymes, and gene expression of corticotropin receptor Surgery 125 1999 396 402
22. F. Sciarra, C. Tosti-Croce, and V. Toscano Androgen-secreting adrenal tumors Minerva Endocrinol 20 1995 63 68
23. J.H. Mattox, and S. Phelan The evaluation of adult females with testosterone producing neoplasms of the adrenal cortex Surg Gynecol Obstet 164 1987 98 101
24. S.S. Solomon, S.P. Swersie, C.A. Paulsen, and E.G. Biglieri Feminizing adrenocortical carcinoma with hypertension J Clin Endocrinol Metab 28 1968 608 612
25. G. Cathelineau, and R. Poizat [Feminishing adrenal tumor with primary hyperaldosteronism. Report of a case (author's transl)] Ann Endocrinol (Paris) 37 1976 59 60
26. D. McAreavey, A.M. Cumming, and K. Boddy The renin-angiotensin system and total body sodium and potassium in hypertensive women taking oestrogen-progestagen oral contraceptives Clin Endocrinol (Oxf) 18 1983 111 118
27. B. Barcelo, J. Abascal, and J. Ardaiz Feminizing adrenocortical carcinoma in a postmenopausal woman Postgrad Med J 55 1979 406 408
28. T.J. McKenna, Y. O'Connell, S. Cunningham, M. McCabe, and M. Culliton Steroidogenesis in an estrogen-producing adrenal tumor in a young woman: comparison with steroid profiles associated with cortisol- and androgen-producing tumors J Clin Endocrinol Metab 70 1990 28 34
29. T. Watanabe, T. Yasuda, and H. Noda Estrogen secreting adrenal adenocarcinoma in an 18-month-old boy Aromatase activity, protein expression, mRNA and utilization of gonadal type promoter Endocr J 47 2000 723 730
30. M.B. Desai, and S.N. Kapadia Feminizing adrenocortical tumors in male patients: adenoma versus carcinoma J Urol 139 1988 101 103
31. S.L. Simpson, and C.A. Joll Feminization in a male adult with carcinoma of the adrenal cortex Endocrinology 22 1938 595 604
32. M. Fassnacht, W. Kenn, and B. Allolio Adrenal tumors: how to establish malignancy J Endocrinol Invest 27 2004 387 399
33. S. Moreno, M. Guillermo, M. Decoulx, D. Dewailly, R. Bresson, and C. Proye Feminizing adreno-cortical carcinomas in male adults. A dire prognosis. Three cases in a series of 801 adrenalectomies and review of the literature Ann Endocrinol (Paris) 67 2006 32 38
34. J.L. Gabrilove, D.C. Sharma, H.H. Wotiz, and R.I. Dorfman Feminizing adrenocortical tumors in the male A review of 52 cases including a case report Medicine (Baltimore) 44 1965 37 79
35. E. Bhettay, and F. Bonnici Pure oestrogen-secreting feminizing adrenocortical adenoma Arch Dis Child 52 1977 241 243
36. A. Zayed, J.L. Stock, M.K. Liepman, M. Wollin, and C. Longcope Feminization as a result of both peripheral conversion of androgens and direct estrogen production from an adrenocortical carcinoma J Endocrinol Invest 17 1994 275 278
37. M. Kimura, N. Itoh, T. Tsukamoto, Y. Kumamoto, Y. Takagi, and Y. Mori Aromatase activity in an estrogen-producing adrenocortical carcinoma in a young man J Urol 153 1995 1039 1040
38. J. Young, S. Bulun, and V. Agarwal Aromatase expression in a feminizing adrenocortical tumor J Clin Endocrinol Metab 81 1996 3173 3176
39. T. Goto, O. Murakami, F. Sato, M. Haraguchi, K. Yokoyama, and H. Sasano Oestrogen producing adrenocortical adenoma: clinical, biochemical and immunohistochemical studies Clin Endocrinol (Oxf) 45 1996 643 648
40. H. Bourama, B. Lireux, and H. Mittre Major hyperestrogenism in a feminizing adrenocortical adenoma despite a moderate overexpression of the aromatase enzyme Eur J Endocrinol 148 2003 457 461
41. M.R. Nicol, G. Papacleovoulou, and D.B. Evans Estrogen biosynthesis in human H295 adrenocortical carcinoma cells Mol Cell Endocrinol 300 2009 115 120
42. X. Shen, C. Gu, Y. Qiu, C. Du, Y. Fu, and J. Wu Estrogen receptor expression in adrenocortical carcinoma J Zhejiang Univ Sci B 10 2009 1 6
43. R. Azziz, K.S. Woods, R. Reyna, T.J. Key, E.S. Knochenhauer, and B.O. Yildiz The prevalence and features of the polycystic ovary syndrome in an unselected population J Clin Endocrinol Metab 89 2004 2745 2749
44. S. Franks Polycystic ovary syndrome N Engl J Med 333 1995 853 861
45. R.S. Rittmaster Hirsutism Lancet 349 1997 191 195
46. G.A. Kaltsas, A.M. Isidori, and B.P. Kola The value of the low-dose dexamethasone suppression test in the differential diagnosis of hyperandrogenism in women J Clin Endocrinol Metab 88 2003 2634 2643
47. K.A. Martin, R.J. Chang, and D.A. Ehrmann Evaluation and treatment of hirsutism in premenopausal women: an Endocrine Society clinical practice guideline J Clin Endocrinol Metab 93 2008 1105 1120
48. J.B. O'Driscoll, H. Mamtora, J. Higginson, A. Pollock, J. Kane, and D.C. Anderson A prospective study of the prevalence of clear-cut endocrine disorders and polycystic ovaries in 350 patients presenting with hirsutism or androgenic alopecia Clin Endocrinol (Oxf) 41 1994 231 236
49. W. Waggoner, L.R. Boots, and R. Azziz Total testosterone and DHEAS levels as predictors of androgen-secreting neoplasms: a populational study Gynecol Endocrinol 13 1999 394 400
50. C.B. d'Alva, G. Abiven-Lepage, and V. Viallon Sex steroids in androgen-secreting adrenocortical tumors: clinical and hormonal features in comparison with non-tumoral causes of androgen excess Eur J Endocrinol 159 2008 641 647
51. D.A. Ehrmann, and R.L. Rosenfield Clinical review 10: an endocrinologic approach to the patient with hirsutism J Clin Endocrinol Metab 71 1990 1 4
52. G.E. Abraham, G.B. Maroulis, J.E. Buster, R.J. Chang, and J.R. Marshall Effect of dexamethasone on serum cortisol and androgen levels in hirsute patients Obstet Gynecol 47 1976 395 402
53. J. Derksen, S.K. Nagesser, A.E. Meinders, H.R. Haak, and C.J. van de Velde Identification of virilising adrenal tumors in hirsute women N Engl J Med 331 1994 968 973
54. G.A. Kaltsas, J.J. Mukherjee, and B. Kola Is ovarian and adrenal venous catheterization and sampling helpful in the investigation of hyperandrogenic women? Clin Endocrinol (Oxf) 59 2003 34 43
55. E. Fishman, B. Deutch, D. Hartman, S. Goldman, E. Zerhouni, and S. Siegelman Primary adrenocortical carcinoma: CT evaluation with clinical correlation Am J Roentgenol 148 1987 531 535
56. M. Paja, S. Dez, T. Lucas, A. Ojeda, L. Salto, and J. Estrada Dexamethasone-suppressible feminizing adrenal adenoma Postgrad Med J 70 1994 584 588
57. M. Terzolo, A. Al, and G. Osella The value of dehydroepiandrosterone sulfate measurement in the differentiation between benign and malignant adrenal masses Eur J Endocrinol 142 2000 611 617
58. A.A. Kasperlik-Zeluska, E. Rosonowska, and J. Sowinska-Srzednicka Incidentally discovered adrenal mass (incidentaloma): investigation and management of 208 patients Clin Endocrinol (Oxf) 46 1997 29 37
59. Z. Bencsik, I. Szabolcs, and Z. Kovcs Low dehydroepiandrosterone sulfate (DHEA-S) level is not a good predictor of hormonal activity in nonselected patients with incidentally detected adrenal tumors J Clin Endocrinol Metab 81 1996 1726 1729 (Pubitemid 26152453)
60. A. Sahdev, and R.H. Reznek The indeterminate adrenal mass in patients with cancer Cancer Imaging 2007 7 Spec No A:S100-9
61. G.W. Boland, M.J. Lee, G.S. Gazelle, E.F. Halpern, M.M. McNicholas, and P.R. Mueller Characterization of adrenal masses using unenhanced CT: an analysis of the CT literature AJR Am J Roentgenol 171 1998 201 204
62. I. Ilias, A. Sahdev, R.H. Reznek, A.B. Grossman, and K. Pacak The optimal imaging of adrenal tumours: a comparison of different methods Endocr Relat Cancer 14 2007 587 599
63. M. Lockhart, J. Smith, and P. Kenney Imaging of adrenal masses Eur J Radiol 41 2002 95 112
64. J. Slattery, M. Blake, and M. Kalra Adrenocortical carcinoma: contrast washout characteristics on CT AJR Am J Roentgenol 187 2006 W21 W24
65. M.J. Lee, P.F. Hahn, and N. Papanicolaou Benign and malignant adrenal masses: CT distinction with attenuation coefficients, size, and observer analysis Radiology 179 1991 415 418
66. I.R. Francis, M.D. Gross, B. Shapiro, M. Korobkin, and L.E. Quint Integrated imaging of adrenal disease Radiology 184 1992 1 13
67. S. Hussain, A. Belldegrun, S. Seltzer, J. Richie, R. Gittes, and H. Abrams Differentiation of malignant from benign adrenal masses: predictive indices on computed tomography AJR Am J Roentgenol 144 1985 61 65
68. A. Chang, H. Glazer, J. Lee, D. Ling, and J. Heiken Adrenal gland: MR imaging Radiology 163 1987 123 128
69. K. Jhaveri, F. Wong, S. Ghai, and M. Haider Comparison of CT histogram analysis and chemical shift MRI in the characterization of indeterminate adrenal nodules AJR Am J Roentgenol 187 2006 1303 1308
70. M. Korobkin, T.J. Lombardi, and A.M. Aisen Characterization of adrenal masses with chemical shift and gadolinium-enhanced MR imaging Radiology 197 1995 411 418
71. Y. Tsushima, H. Ishizaka, and M. Matsumoto Adrenal masses: differentiation with chemical shift, fast low-angle shot MR imaging Radiology 186 1993 705 709
72. E. Caoili, M. Korobkin, R. Brown, G. Mackie, and B. Shulkin Differentiating adrenal adenomas from nonadenomas using (18)F-FDG PET/CT quantitative and qualitative evaluation Acad Radiol 14 2007 468 475
73. L. Weiss, L. Medeiros, and A. Vickery Jr Pathologic features of prognostic significance in adrenocortical carcinoma Am J Surg Pathol 13 1989 202 206
74. A.D. Del Gaudio, and G.A. Del Gaudio Virilizing adrenocortical tumors in adult women Report of 10 patients, 2 of whom each had a tumor secreting only testosterone Cancer 72 1993 1997 2003
75. O.D. Wolthers, F.J. Cameron, and I. Scheimberg Androgen secreting adrenocortical tumours Arch Dis Child 80 1999 46 50
76. X. Bertagna, L. Groussin, R. Libe, and J. Bertherat [Adrenal cortical carcinoma: advances in the pathophysiology and management of this malignancy] Bull Acad Natl Med 192 2008 87 102
77. R.F. Pommier, and M.F. Brennan An eleven-year experience with adrenocortical carcinoma Surgery 112 1992 963 970
78. A. Stojadinovic, R.A. Ghossein, and A. Hoos Adrenocortical carcinoma: clinical, morphologic, and molecular characterization J Clin Oncol 20 2002 941 950
79. M.J. Demeure, and L.B. Somberg Functioning and nonfunctioning adrenocortical carcinoma: clinical presentation and therapeutic strategies Surg Oncol Clin North Am 7 1998 791 805
80. M. Terzolo, A. Angeli, and M. Fassnacht Adjuvant mitotane treatment for adrenocortical carcinoma N Engl J Med 356 2007 2372 2380
81. A. Berruti, M. Terzolo, and P. Sperone Etoposide, doxorubicin and cisplatin plus mitotane in the treatment of advanced adrenocortical carcinoma: a large prospective phase II trial Endocr Relat Cancer 12 2005 657 666