Romidepsin reduces histone deacetylase activity, induces acetylation of histones, inhibits proliferation, and activates apoptosis in immortalized epithelial endometriotic cells

Fertility and Sterility

Volumn 94, Issue 7, 2010, Pages 2838-2842

  Imesch, Patrick ^a   Fink, Daniel ^a   Fedier, André ^a  

^a UNIVERSITÄTSSPITAL ZÜRICH   (Switzerland)

Author keywords

activity; apoptosis; Endometriosis; endometriotic cells; histone acetylation; histone deacetylase inhibitor; proliferation; romidepsin

Indexed keywords

CYCLIN B1; CYCLIN D1; HISTONE DEACETYLASE; PROTEIN P21; ROMIDEPSIN;

ACETYLATION; APOPTOSIS; ARTICLE; CELL IMMORTALIZATION; CELL PROLIFERATION; DOWN REGULATION; DRUG EFFECT; DRUG SENSITIVITY; ENDOMETRIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; EPIGENETICS; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; UPREGULATION;

ACETYLATION; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CELL LINE, TRANSFORMED; CELL PROLIFERATION; DEPSIPEPTIDES; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; ENDOMETRIOSIS; ENZYME ACTIVATION; EPITHELIAL CELLS; FEMALE; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HISTONES; HUMANS; PERITONEAL DISEASES; UP-REGULATION;

EID: 78650214507     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2010.04.052     Document Type: Article

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