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Volumn 20, Issue 5, 2009, Pages 321-333
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Acquired vorinostat resistance shows partial cross-resistance to 'second-generation' HDAC inhibitors and correlates with loss of histone acetylation and apoptosis but not with altered HDAC and HAT activities.
a
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Author keywords
[No Author keywords available]
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Indexed keywords
ANTINEOPLASTIC AGENT;
BENZAMIDE DERIVATIVE;
DEPSIPEPTIDE;
HISTONE;
HISTONE ACETYLTRANSFERASE;
HISTONE DEACETYLASE;
HYDROXAMIC ACID;
JNJ 26481585;
MULTIDRUG RESISTANCE PROTEIN;
MULTIDRUG RESISTANCE PROTEIN 1;
MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1;
N (2 AMINOPHENYL) 4 ((4 PYRIDIN 3 YLPYRIMIDIN 2 YLAMINO)METHYL)BENZAMIDE;
N-(2-AMINOPHENYL)-4-((4-PYRIDIN-3-YLPYRIMIDIN-2-YLAMINO)METHYL)BENZAMIDE;
PANOBINOSTAT;
PYRIMIDINE DERIVATIVE;
ROMIDEPSIN;
TUMOR PROTEIN;
VORINOSTAT;
ACETYLATION;
ADENOCARCINOMA;
APOPTOSIS;
ARTICLE;
COLORECTAL TUMOR;
DRUG ANTAGONISM;
DRUG EFFECT;
DRUG RESISTANCE;
DRUG SCREENING;
ENZYMOLOGY;
FEMALE;
GENE;
HELA CELL;
HUMAN;
IC 50;
METABOLISM;
MULTIDRUG RESISTANCE;
PATHOLOGY;
PROTEIN PROCESSING;
TUMOR CELL LINE;
ACETYLATION;
ADENOCARCINOMA;
ANTINEOPLASTIC AGENTS;
APOPTOSIS;
BENZAMIDES;
CELL LINE, TUMOR;
COLORECTAL NEOPLASMS;
DEPSIPEPTIDES;
DRUG RESISTANCE, MULTIPLE;
DRUG RESISTANCE, NEOPLASM;
FEMALE;
GENES, MDR;
HELA CELLS;
HISTONE ACETYLTRANSFERASES;
HISTONE DEACETYLASES;
HISTONES;
HUMANS;
HYDROXAMIC ACIDS;
INHIBITORY CONCENTRATION 50;
MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS;
NEOPLASM PROTEINS;
PROTEIN PROCESSING, POST-TRANSLATIONAL;
PYRIMIDINES;
TUMOR STEM CELL ASSAY;
MLCS;
MLOWN;
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EID: 67650296574
PISSN: None
EISSN: 14735741
Source Type: Journal
DOI: 10.1097/cad.0b013e3283262a32 Document Type: Article |
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Times cited : (41)
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References (0)
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