Chronic exposure to aluminum reduces tyrosine hydroxylase expression in the substantia nigra and locomotor performance in rats

Neuroscience Letters

Volumn 487, Issue 1, 2011, Pages 8-11

  Erazi, Hasna ^a   Ahboucha, Samir ^a   Gamrani, Halima ^a  

^a FACULTÉ DES SCIENCES SEMLALIA   (Morocco)

Author keywords

Aluminum; Chronic poisoning; Immunohistochemistry; Locomotor activity; Rat; Tyrosine hydroxylase

Indexed keywords

ALUMINUM; DRINKING WATER; TYROSINE 3 MONOOXYGENASE;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LABELING; CONTROLLED STUDY; DOPAMINE METABOLISM; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LOCOMOTION; LONG TERM EXPOSURE; MALE; MOTOR PERFORMANCE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SUBSTANTIA NIGRA;

ALUMINUM; ANIMALS; BEHAVIOR, ANIMAL; FEMALE; MALE; MOTOR ACTIVITY; RATS; RATS, WISTAR; SUBSTANTIA NIGRA; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

EID: 78650214326     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.09.053     Document Type: Article

References (24)

1. Bhalla P., Garg M.L., Dhawan D.K. Protective role of lithium during aluminium-induced neurotoxicity. Neurochem. Int. 2010, 56:256-262.
2. Carpenter D.O. Effects of metals on the nervous system of humans and animals. Int. J. Occup. Med. Environ. Health 2001, 14:209-218.
3. Cordeiro J.M., Silva V.S., Oliveira C.R., Gonçalves P.P. Aluminium-induced impairment of Ca2+ modulatory action on GABA transport in brain cortex nerve terminals. J. Inorg. Biochem. 2003, 97:132-142.
4. Erazi H., Sansar W., Ahboucha S., Gamrani H. Aluminum affects glial system and behavior of rats. C. R. Biol. 2010, 333:23-27.
5. Golub M.S., Donald J.M., Gershwin M.E., Keen C.L. Effects of aluminum ingestion on spontaneous motor activity of mice. Neurotoxicol. Teratol. 1989, 11:231-235.
6. Gonda Z., Lehotzky K., Miklósi A. Neurotoxicity induced by prenatal aluminum exposure in rats. Neurotoxicology 1996, 17:459-469.
7. Gutteridge J.M.C., Quinlan G.J., Clark I., Halliwell B. Aluminium salts accelerate peroxidation of membrane lipids stimulated by iron salts. Biochem. Biophys. Acta 1985, 835:441-447.
8. Hofstetter J.R., Vincent I., Bugiani O., Ghetti B., Richter J.A. Aluminum-induced decreases in choline acetyltransferase, tyrosine hydroxylase, and glutamate decarboxylase in selected regions of rabbit brain. Neurochem. Pathol. 1987, 6:177-193.
9. Kim S., Nam J., Kim K. Aluminum exposure decreases dopamine D1 and D2 receptor expression in mouse brain. Hum. Exp. Toxicol. 2007, 26:741-746.
10. Marinho C.R., Manso C.F. Effect of aluminum on the non-enzymatic oxidation of dopamine. Acta Med. Port. 1994, 7:611-615.
11. Milanese M., Lkhayat M.I., Zatta P. Inhibitory effect of aluminum on dopamine β-hydroxylase from bovine adrenal gland. Trace Elem. Med. Biol. 2001, 15:139-141.
12. Misawa T., Shigeta S. Effects of prenatal aluminum treatment on development and behavior in the rat. J. Toxicol. Sci. 1993, 18:43-48.
13. Miu A.C., Andreescu C.E., Vasiu R., Olteanu A.I. A behavioral and histological study of the effects of long-term exposure of adult rats to aluminum. Int. J. Neurosci. 2003, 113:1197-1211.
14. Nayak P., Chatterjee A.K. Effects of aluminium exposure on brain glutamate and GABA systems: an experimental study in rats. Food Chem. Toxicol. 2001, 39:1285-1289.
15. Nehru B., Anand P. Oxidative damage following chronic aluminium exposure in adult and pup rat brains. J. Trace Elem. Med. Biol. 2005, 19:203-208.
16. Pallavi S., Amar J., Rameshwar S., Ejaz H. Aluminium-induced electrophysiological, biochemical and cognitive modifications in the hippocampus of aging rats. Neurotoxicology 2008, 29:1069-1079.
17. Ravi S.M., Prabhu B.M., Raju T.R., Bindu P.N. Long-term effects of postnatal aluminium exposure on acetylcholinesterase activity and biogenic amine neurotransmitters in rat brain. Indian J. Physiol. Pharmacol. 2000, 44:473-478.
18. Sánchez-Iglesias S., Méndez-Alvarez E., Iglesias-González J., Muñoz-Patiño A., Sánchez-Sellero I., Labandeira-García J.L., Soto-Otero R. Brain oxidative stress and selective behaviour of aluminium in specific areas of rat brain: potential effects in a 6-OHDA-induced model of Parkinson's disease. J. Neurochem. 2009, 109:879-888.
19. Tsunoda M., Sharma R.P. Altered dopamine turnover in murine hypothalamus after low-dose continuous oral administration of aluminum. J. Trace Elem. Med. Biol. 1999, 13:224-231.
20. Wenk G.L., Stemmer K.L. The influence of ingested aluminum upon norepinephrine and dopamine levels in the rat brain. Neurotoxicology 1981, 2:347-353.
21. Yumoto S., Kakimi S., Ohsaki A., Ishikawa A. Demonstration of aluminum in amyloid fibers in the cores of senile plaques in the brains of patients with Alzheimer's disease. J. Inorg. Biochem. 2009, 103:1579-1584.
22. Zatta P., Kiss T., Suwalsky M., Berthon G. Aluminium as a promoter of cellular oxidation. Coord. Chem. Rev. 2002, 228:271-284.
23. Zhang F., Bi S., Liu J., Yang X., Wang X., Yang L., Yu T., Chen Y., Dai L., Yang T. Application of dopamine as an electroactive ligand for the determination of aluminum in biological fluids. Anal. Sci. 2002, 18:293-299.
24. Zhang J.Z., Yi H.Q., Hai T.H., Jie Y., Guang-De Y. The herbal medicine Dipsacus asper Wall extract reduces the cognitive deficits and overexpression of β-amyloid protein induced by aluminum exposure. Life Sci. 2003, 73:2443-2454.