Aluminum exposure decreases dopamine D1 and D2 receptor expression in mouse brain

Human and Experimental Toxicology

Volumn 26, Issue 9, 2007, Pages 741-746

  Kim, Sunyoun ^a   Nam, Jungmin ^b   Kim, Kisok ^b  

^a Biotoxtech Co Ltd   (South Korea)

^b Keimyung University   (South Korea)

Author keywords

Dopaminergic neurotransmission; Neurodegenerative disease; Neurotoxicity; Rostrocaudal extent

Indexed keywords

ALUMINUM; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; EXPOSURE; IMMUNOREACTIVITY; MALE; MOUSE; NEUROTOXICITY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL;

ALUMINUM COMPOUNDS; ANIMALS; BASAL GANGLIA; CEREBRAL CORTEX; CHLORIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENVIRONMENTAL POLLUTANTS; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAPERITONEAL; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2;

MUS;

EID: 36349019184     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1177/0960327107083973     Document Type: Article

References (31)

1. Jope RS, Johnson GV. Neurotoxic effects of dietary aluminum. Ciba Found Symp 1992; 169: 254-62.
2. Gupta VB, Anitha S, Hegde ML, Zecca L, Garruto RM, Ravid R. Aluminium in Alzheimer's disease: are we still at a crossroad? Cell Mol Life Sci 2005; 62: 143-58.
3. Yokel RA. Brain uptake, retention and efflux of aluminum and manganese. Environ Health Perspect 2002; 110(Suppl 5): 699-704.
4. Yokel RA, Rhineheimer SS, Sharma P, Elmore D, McNamara PJ. Entry, half-life, and desferrioxamine-accelerated clearance of brain aluminum after a single (26)Al exposure. Toxicol Sci 2001; 64: 77-82.
5. Gulya K, Rakonczay Z, Kasa P. Cholinotoxic effects of aluminum in rat brain. J Neurochem 1990; 54: 1020-6.
6. Yokel RA. The toxicology of aluminum in the brain: a review. Neurotoxicology 2000; 21: 813-28.
7. Miu AC, Benga O. Aluminum and Alzheimer's disease: a new look. J Alzheimers Dis 2006; 10: 179-201.
8. Platt B, Haas H, Busselberg D. Aluminum reduces glutamate-activated currents of rat hippocampal neurons. Neuroreport 1994; 5: 2329-32.
9. Quintal-Tun F, Munoz-Sanchez JA, Ramos-Diaz A, Escamilla-Bencomo A, Martinez-Estevez M, Exley C, Hernandez-Sotomayor SM. Aluminium-induced phospholipid signal transduction pathway in Coffea arabica suspension cells and its amelioration by silicic acid. J Inorg Biochem 2007; 101: 362-9.
10. Nostrandt AC, Shafer TJ, Mundy WR, Padilla S. Inhibition of rat brain phosphatidylinositol-specific phospholipase C by aluminum: regional differences, interactions with aluminum salts, and mechanisms. Toxicol Appl Pharmacol 1996; 136: 118-25.
11. Kim K. Perinatal exposure to aluminum alters neuronal nitric oxide synthase expression in the frontal cortex of rat offspring. Brain Res Bull 2003; 61: 437-41.
12. Milanese M, Lkhayat MI, Zatta P. Inhibitory effect of aluminum on dopamine beta-hydroxylase from bovine adrenal gland. J Trace Elem Med Biol 2001; 15: 139-41.
13. Wenk GL, Stemmer KL. The influence of ingested aluminum upon norepinephrine and dopamine levels in the rat brain. Neurotoxicology 1981; 2: 347-53.
14. Missale C, Nash SR, Robinson SW, Jaber M, Caron MG. Dopamine receptors: from structure to function. Physiol Rev 1998; 78: 189-225.
15. Lachowicz JE, Sibley DR. Molecular characteristics of mammalian dopamine receptors. Pharmacol Toxicol 1997; 81: 105-13.
16. Clark D, White FJ. D1 dopamine receptor-the search for a function: a critical evaluation of the D1/D2 dopamine receptor classification and its functional implications. Synapse 1987; 1: 347-88.
17. Paxinos G, Franklin KBJ. The mouse brain in stereotaxic coordinates, second edition. Academic Press, 2004.
18. Walton JR. Aluminum in hippocampal neurons from humans with Alzheimer's disease. Neurotoxicology 2006; 27: 385-94.
19. Tsunoda M, Sharma RP. Altered dopamine turnover in murine hypothalamus after low-dose continuous oral administration of aluminum. J Trace Elem Med Biol 1999; 13: 224-31.
20. Zatta P, Lucchini R, van Rensburg SJ, Taylor A. The role of metals in neurodegenerative processes: aluminum, manganese, and zinc. Brain Res Bull 2003; 62: 15-28.
21. Canales JJ, Corbalan R, Montoliu C, Llansola M, Monfort P, Erceg S. Aluminum impairs the glutamatenitric oxide-cGMP pathway in cultured neurons and in rat brain in vivo: molecular mechanisms and implications for neuropathology. J Inorg Biochem 2001; 87: 63-9.
22. Lee FJ, Xue S, Pei L, Vukusic B, Chery N, Wang Y. Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor. Cell 2002; 111: 219-30.
23. Bouthenet ML, Souil E, Martres MP, Sokoloff P, Giros B, Schwartz JC. Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA. Brain Res 1991; 564: 203-19.
24. Weiner DM, Levey AI, Sunahara RK, Niznik HB, O'Dowd BF, Seeman P. D1 and D2 dopamine receptor mRNA in rat brain. Pro Natl Acad Sci USA 1991; 88: 59-63.
25. Hurd YL, Suzuki M, Sedvall GC. D1 and D2 dopamine receptor mRNA expression in whole hemisphere sections of the human brain. J Chem Neuroanat 2001; 22: 127-37.
26. Kumar S. Aluminium-induced biphasic effect. Med Hypotheses 1999; 52: 557-9.
27. Exley C, Birchall JD. The cellular toxicity of aluminum. J Theor Biol 1992; 159: 183-98.
28. Roig JL, Fuentes S, Teresa Colomina M, Vicens P, Domingo JL. Aluminum, restraint stress and aging: behavioral effects in rats after 1 and 2 years of aluminum exposure. Toxicology 2006; 218: 112-24.
29. Greger JL. Aluminum metabolism. Ann Rev Nutr 1993; 13: 43-63.
30. Piggott MA, Marshall EF, Thomas N, Lloyd S, Court JA, Jaros E. Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution. Brain 1999; 122: 1449-68.
31. Kemppainen N, Ruottinen H, Nagren K, Rinne JO. PET shows that striatal dopamine D1 and D2 receptors are differentially affected in AD. Neurology 2000; 55: 205-9.