One-pot multicomponent synthesis of two novel thiolactone scaffolds

Molecular Diversity

Volumn 14, Issue 3, 2010, Pages 479-491

  Beck, B ^a   Srivastava, S ^a   Khoury, K ^a   Herdtweck, E ^b   Dömling, Alexander ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Isocyanide; Multicomponent reaction (MCR); Thiolactone; Virtual library

Indexed keywords

1 OXO OCTAHYDRO PYRIDO[2,1 C][1,4]THIAZINE 4 CARBOXYLIC ACID (2,4,6 TRIMETHYL PHENYL)AMIDE; 1 OXO OCTAHYDRO PYRIDO[2,1 C][1,4]THIAZINE 4 CARBOXYLIC ACID TERT BUTYLAMIDE; 1(2 OXO TETRAHYDRO THIOPHEN 3 YLAMINO)CYCLOHEXANECARBOXYLIC ACID(2,4,6 TRIMETHYL PHENYL)AMIDE; 2 METHYL 2 (2 OXO TETRAHYDRO THIOPHEN 3 YLAMINO)N(2,4,6 TRIMETHYL PHENYL)PROPIONAMIDE; 3 METHYL 2 (2 OXO TETRAHYDRO THIOPHEN 3 YLAMINO)N(2,4,6 TRIMETHYL PHENYL)BUTYRAMIDE; 4,8 DIMETHYL 2 (2 OXO TETRAHYDRO THIOPHEN 3 YLAMINO)NON 7 ENOIC ACID BENZHYDRYL AMIDE; 5 (2 METHYLSULFANYL ETHYL) 6 OXO THIOMORPHOLINE 3 CARBOXYLIC ACID(1 PROPYL BUTYL)AMIDE; 5 BENZYL 6 OXO THIOMORPHOLINE 3 CARBOXYLIC ACID BENZYLAMIDE; 5 BENZYL 6 OXO THIOMORPHOLINE 3 CARBOXYLIC ACID[(METHYL PHENETHYL CARBAMOYL)METHYL]AMIDE; 5 C(1 HYDROXY ETHYL) 6 OXO THIOMORPHOLINE 3 CARBOXYLIC ACID(2 FLUORO PHENYL) AMIDE; 5 ISOPROPYL 6 OXO THIOMORPHOLINE 3 CARBOXYLIC ACID [2 OXO 2 (4 PHENYL PIPERAZIN 1 YL)ETHYL]AMIDE; 5 METHYL 6 OXO THIOMORPHOLINE 3 CARBOXYLIC ACID(2,4,6 TRIMETHYL PHENYL)AMIDE; 5 SEC BUTYL 6 OXO THIOMORPHOLINE 3 CARBOXYLIC ACID TERT BUTYLAMIDE; [(1 OXO HEXAHYDRO PYRROLO[2,1 C][1,4]THIAZINE 4 CARBONYL)AMINO]ACETIC ACID METHYL ESTER; ERDOSTEINE; MOLECULAR SCAFFOLD; N BENZHYDRYL 2 (2 OXO TETRAHYDRO THIOPHEN 3 YLAMINO) 3 PHENYL PROPIONAMIDE; N BENZYL 2 (2 OXO TETRAHYDRO THIOPHEN 3 YLAMINO) 4 PHENYL BUTYRAMIDE; N BENZYL 2 CYCLOPROPYL 2 (2 OXO TETRAHYDRO THIOPHEN 3 YLAMINO)ACETAMIDE; N TERT BUTYL 2 NAPHTHALEN 2 YL 2 (2 OXO TETRAHYDRO THIOPHEN 3 YLAMINO)ACETAMIDE; N TERT BUTYL 3 (5 METHYL 2,4 DIOXO 3,4 DIHYDRO 2H PYRIMIDIN 1 YL) 2 (2 OXO TETRAHYDRO THIOPHEN 3 YLAMINO)PROPIONAMIDE; N TERT BUTYL 3 METHYL 2 (2 OXOTETRAHYDRO THIOPHEN 3 YLAMINO)BUTYRAMIDE; PRASUGREL; THIOLACTOMYCIN; THIOLACTONE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ONE POT SYNTHESIS; PRIORITY JOURNAL; STEREOCHEMISTRY;

ACYLATION; CHEMISTRY, ORGANIC; LACTONES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MORPHOLINES; THIOPHENES;

EID: 78650176366     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11030-010-9249-2     Document Type: Article

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