MDM2 promotes the proteasomal degradation of p73 through the interaction with Itch in HeLa cells

Biochemical and Biophysical Research Communications

Volumn 403, Issue 3-4, 2010, Pages 405-411

  Kubo, Natsumi ^a   Okoshi, Rintaro ^a   Nakashima, Kumiko ^a   Shimozato, Osamu ^a   Nakagawara, Akira ^a   Ozaki, Toshinori ^a  

^a CHIBA CANCER CENTER   (Japan)

Author keywords

Adriamycin; Itch; MDM2; P73; Proteasome

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; DOXORUBICIN; PROTEIN; PROTEIN ITCH; PROTEIN MDM2; PROTEIN P73; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY;

ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; DNA-BINDING PROTEINS; DOXORUBICIN; HELA CELLS; HUMANS; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS C-MDM2; REPRESSOR PROTEINS; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES;

EID: 78650175204     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.11.043     Document Type: Article

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