Purification and characterization of a recombinant Yersinia pestis V-F1 "reversed" fusion protein for use as a new subunit vaccine against plague

Protein Expression and Purification

Volumn 76, Issue 1, 2011, Pages 136-144

  Goodin, Jeremy L ^a,d   Powell, Bradford S ^a   Enama, Jeff T ^a   Raab, Ronald W ^b   McKown, Robert L ^b   Coffman, George L ^b   Andrews, Gerard P ^c  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^b JAMES MADISON UNIVERSITY   (United States)

^c UNIVERSITY OF WYOMING   (United States)

^d EISENHOWER ARMY MEDICAL CENTER   (United States)

Author keywords

Caf1; F1 V; F1S V F1; Vaccine; Yersinia pestis

Indexed keywords

BACTERIAL ANTIGEN; HYBRID PROTEIN; LCRV PROTEIN, YERSINIA; NEUTRALIZING ANTIBODY; PLAGUE VACCINE; PORE FORMING CYTOTOXIC PROTEIN; SUBUNIT VACCINE;

AFFINITY CHROMATOGRAPHY; ARTICLE; BIOSYNTHESIS; GENETICS; IMMUNOLOGY; ION EXCHANGE CHROMATOGRAPHY; PLAGUE; YERSINIA PESTIS;

ANTIBODIES, NEUTRALIZING; ANTIGENS, BACTERIAL; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, ION EXCHANGE; PLAGUE; PLAGUE VACCINE; PORE FORMING CYTOTOXIC PROTEINS; RECOMBINANT FUSION PROTEINS; VACCINES, SUBUNIT; YERSINIA PESTIS;

ESCHERICHIA COLI; YERSINIA PESTIS;

EID: 78650171693     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pep.2010.10.011     Document Type: Article

References (30)

1. T.V. Inglesby, D.T. Dennis, D.A. Henderson, J.G. Bartlett, M.S. Ascher, E. Eitzen, A.D. Fine, A.M. Friedlander, J. Hauer, J.F. Koerner, M. Layton, J. McDade, M.T. Osterholm, T. O'Toole, G. Parker, T.M. Perl, P.K. Russell, M. Schoch-Spana, and K. Tonat Plague as a biological weapon: medical and public health management JAMA 283 2000 2281 2290 (Pubitemid 30246781)
2. R.W. Titball, and E.D. Williamson Vaccination against bubonic and pneumonic plague Vaccine 19 2001 4175 4184 (Pubitemid 32703638)
3. M.L.M. Pitt, E.J. Estep, S.L. Weldos, and A.M. Friedlander In: Proceedings of the Abstracts of the 94th General Meeting of the American Society for Microbiology 1994 Washington DC
4. D.G. Heath, G.W. Anderson Jr., J.M. Mauro, S.L. Welkos, G.P. Andrews, J. Adamovicz, and A.M. Friedlander Protection against experimental bubonic and pneumonic plague by a recombinant capsular F1-V antigen fusion protein vaccine Vaccine 16 1998 1131 1137 (Pubitemid 28307882)
5. D.A. Chapman, A.V. Zavialov, T.V. Chernovskaya, A.V. Karlyshev, G.A. Zav'yalova, A.M. Vasiliev, I.V. Dudich, V.M. Abramov, V.P. Zav'yalov, and S. MacIntyre Structural and functional significance of the FGL sequence of the periplasmic chaperone Caf1M of Yersinia pestis J. Bacteriol. 181 1999 2422 2429 (Pubitemid 29181564)
6. E.E. Galyov, A.V. Karlishev, T.V. Chernovskaya, D.A. Dolgikh, O.Y. Smirnov, K.I. Volkovoy, V.M. Abramov, and V.P. Zav'yalov Expression of the envelope antigen F1 of Yersinia pestis is mediated by the product of caf1M gene having homology with the chaperone protein PapD of Escherichia coli FEBS Lett. 286 1991 79 82
7. S. MacIntyre, I.M. Zyrianova, T.V. Chernovskaya, M. Leonard, E.G. Rudenko, V.P. Zav'yalov, and D.A. Chapman An extended hydrophobic interactive surface of Yersinia pestis Caf1M chaperone is essential for subunit binding and F1 capsule assembly Mol. Microbiol. 39 2001 12 25 (Pubitemid 32057672)
8. V.P. Zav'yalov, G.A. Zav'yalova, A.I. Denesyuk, and T. Korpela Modelling of steric structure of a periplasmic molecular chaperone Caf1M of Yersinia pestis, a prototype member of a subfamily with characteristic structural and functional features FEMS Immunol. Med. Microbiol. 11 1995 19 24
9. G.E. Soto, and S.J. Hultgren Bacterial adhesins: common themes and variations in architecture and assembly J. Bacteriol. 181 1999 1059 1071 (Pubitemid 29119542)
10. A.V. Karlyshev, E.E. Galyov, O.Y. Smirnov, A.P. Guzayev, V.M. Abramov, and V.P. Zav'yalov A new gene of the f1 operon of Y. Pestis involved in the capsule biogenesis FEBS Lett. 297 1992 77 80
11. V.P. Zav'yalov, T.V. Chernovskaya, D.A. Chapman, A.V. Karlyshev, S. MacIntyre, A.V. Zavialov, A.M. Vasiliev, A.I. Denesyuk, G.A. Zav'yalova, I.V. Dudich, T. Korpela, and V.M. Abramov Influence of the conserved disulphide bond, exposed to the putative binding pocket, on the structure and function of the immunoglobulin-like molecular chaperone Caf1M of Yersinia pestis Biochem. J. 324 1997 571 578 (Pubitemid 27268004)
12. A.V. Zavialov, N.V. Batchikova, T. Korpela, L.E. Petrovskaya, V.G. Korobko, J. Kersley, S. MacIntyre, and V.P. Zav'yalov Secretion of recombinant proteins via the chaperone/usher pathway in Escherichia coli Appl. Environ. Microbiol. 67 2001 1805 1814 (Pubitemid 33644954)
13. G.W. Anderson Jr, D.G. Heath, C.R. Bolt, S.L. Welkos, and A.M. Friedlander Short- and long-term efficacy of single-dose subunit vaccines against Yersinia pestis in mice Am. J. Trop. Med. Hyg. 58 1998 793 799 (Pubitemid 28307401)
14. R.W. Titball, A.M. Howells, P.C. Oyston, and E.D. Williamson Expression of the Yersinia pestis capsular antigen (F1 antigen) on the surface of an aroA mutant of Salmonella typhimurium induces high levels of protection against plague Infect. Immun. 65 1997 1926 1930 (Pubitemid 27193620)
15. S.E. Leary, K.F. Griffin, H.S. Garmory, E.D. Williamson, and R.W. Titball Expression of an F1/V fusion protein in attenuated Salmonella typhimurium and protection of mice against plague Microb. Pathog. 23 1997 167 179 (Pubitemid 27387534)
16. D.J. Weber, and W.A. Rutala Immunization of immunocompromised persons Immunol. Allergy Clin. North Am. 23 2003 605 634 (Pubitemid 38030161)
17. D.G. Thanassi, and S.J. Hultgren Multiple pathways allow protein secretion across the bacterial outer membrane Curr. Opin. Cell Biol. 12 2000 420 430 (Pubitemid 30453591)
18. A.K. Panda Bioprocessing of therapeutic proteins from the inclusion bodies of Escherichia coli Adv. Biochem. Eng. Biotechnol. 85 2003 43 93
19. P. Braun, and J. LaBaer High throughput protein production for functional proteomics Trends Biotechnol. 21 2003 383 388 (Pubitemid 37025775)
20. G.P. Andrews, D.G. Heath, G.W. Anderson Jr., S.L. Welkos, and A.M. Friedlander Fraction 1 capsular antigen (F1) purification from Yersinia pestis CO92 and from an Escherichia coli recombinant strain and efficacy against lethal plague challenge Infect. Immun. 64 1996 2180 2187 (Pubitemid 26167232)
21. F.G. Sauer, K. Futterer, J.S. Pinkner, K.W. Dodson, S.J. Hultgren, and G. Waksman Structural basis of chaperone function and pilus biogenesis Science 285 1999 1058 1061
22. P. Denfle, S. Kovarik, T. Ciora, N. Gosselet, J.C. Bénichou, M. Latta, F. Guinet, A. Ryter, and J.F. Mayaux Heterologous protein export in Escherichia coli: influence of bacterial signal peptides on the export of human interleukin1β Gene 85 1989 499 510 (Pubitemid 20067388)
23. P. Klemm, and M.A. Schembri Fimbrial surface display systems in bacteria: from vaccines to random libraries Microbiology 146 2000 3025 3032 (Pubitemid 32040810)
24. B. Stentebjerg-Olesen, L. Pallesen, L.B. Jensen, G. Christiansen, and P. Klemm Authentic display of a cholera toxin epitope by chimeric type 1 fimbriae: effects of insert position and host background Microbiology 143 1997 2027 2038 (Pubitemid 27290295)
25. A.P. White, S.K. Collinson, P.A. Banser, D.J. Dolhaine, and W.W. Kay Salmonella enteritidis fimbriae displaying a heterologous epitope reveal a uniquely flexible structure and assembly mechanism J. Mol. Biol. 296 2000 361 372
26. G. Georgiou, C. Stathopoulos, P.S. Daugherty, A.R. Nayak, B.L. Iverson, and R. Curtiss III Display of heterologous proteins on the surface of microorganisms: from the screening of combinatorial libraries to live recombinant vaccines Nat. Biotechnol. 15 1997 29 34 (Pubitemid 27024144)
27. B.S. Powell, G.P. Andrews, J.T. Enama, S. Jendrek, C. Bolt, P. Worsham, J.K. Pullen, W. Ribot, H. Hines, L. Smith, D.G. Heath, and J.J. Adamovicz Design and testing for a nontagged F1-V fusion protein as vaccine antigen against bubonic and pneumonic plague Biotechnol. Prog. 21 2005 1490 1510 (Pubitemid 41443005)
28. J. Miller, E.D. Williamson, J.H. Lakey, M.J. Pearce, S.M. Jones, and R.W. Titball Macromolecular organisation of recombinant Yersinia pestis F1 antigen and the effect of structure on immunogenicity FEMS Immunol. Med. Microbiol. 21 1998 213 221 (Pubitemid 28356843)
29. A.V. Zavialov, and S.D. Knight A novel self-capping mechanism controls aggregation of periplasmic chaperone Caf1M Mol. Microbiol. 64 2007 153 164 (Pubitemid 46435038)
30. F.G. Sauer, H. Remaut, S.J. Hultgren, and G. Waksman Fiber assembly by the chaperone-usher pathway Biochim. Biophys. Acta 1694 2004 259 267 (Pubitemid 39535073)