Inhibition of neurotrophin receptor p75 intramembran proteolysis by gamma-secretase inhibitor reduces medulloblastoma spinal metastasis

Biochemical and Biophysical Research Communications

Volumn 403, Issue 3-4, 2010, Pages 264-269

  Wang, XiaoJi ^a   Cui, Min ^b   Wang, Lei ^b   Chen, XueHong ^c   Xin, Pan ^d  

^a JIANGXI SCIENCE AND TECHNOLOGY NORMAL UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

^c QINGDAO UNIVERSITY   (China)

^d SHANDONG UNIVERSITY   (China)

Author keywords

Secretase inhibitor; Medulloblastoma spinal metastasis; P75NTR proteolysis

Indexed keywords

GAMMA SECRETASE INHIBITOR; NEUROTROPHIN RECEPTOR P75; REGULATOR PROTEIN;

ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INVASION; CELL INVASION; CELL MEMBRANE; CELL MIGRATION; CONTROLLED STUDY; DRUG INHIBITION; FEMALE; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MEDULLOBLASTOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROCESSING; SPINAL CORD METASTASIS; TUMOR CELL;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CEREBELLAR NEOPLASMS; ENZYME INHIBITORS; FEMALE; HUMANS; MEDULLOBLASTOMA; MICE; MICE, SCID; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; RECEPTOR, NERVE GROWTH FACTOR; SPINAL NEOPLASMS;

EID: 78650170988     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.11.012     Document Type: Article

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