Molecular Interactions between Prions as Seeds and Recombinant Prion Proteins as Substrates Resemble the Biological Interspecies Barrier In Vitro

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Panza, Giannantonio ^a   Luers, Lars ^a   Stöhr, Jan ^a   Nagel Steger, Luitgard ^a   Weib, Jürgen ^b   Riesner, Detlev ^a   Willbold, Dieter ^a,c   Birkmann, Eva ^a,c  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; DODECYL SULFATE SODIUM; PRION PROTEIN; RECOMBINANT PRION PROTEIN; RECOMBINANT PROTEIN; THIOFLAVINE; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL TISSUE; ARTICLE; CATTLE; CONTROLLED STUDY; DISEASE TRANSMISSION; IN VITRO STUDY; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PRION DISEASE; PROTEIN METABOLISM; PROTEIN PURIFICATION; SHEEP; SPECIES DIFFERENCE; SYRIAN HAMSTER; ANIMAL; BRAIN; CHEMISTRY; CIRCULAR DICHROISM; DEGENERATIVE DISEASE; GENETICS; HAMSTER; KINETICS; METABOLISM; PRION; PROTEIN SECONDARY STRUCTURE; ULTRACENTRIFUGATION;

BOS; BOVINAE; MESOCRICETUS AURATUS; OVIS ARIES;

AMYLOID; ANIMALS; BRAIN; CATTLE; CIRCULAR DICHROISM; CRICETINAE; KINETICS; MESOCRICETUS; MICE; NEURODEGENERATIVE DISEASES; PRION DISEASES; PRIONS; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SHEEP; SODIUM DODECYL SULFATE; SPECIES SPECIFICITY; ULTRACENTRIFUGATION;

EID: 78650164509     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014283     Document Type: Article

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