메뉴 건너뛰기




Volumn 27, Issue 12, 2010, Pages 2255-2260

The hormone ghrelin prevents traumatic brain injury induced intestinal dysfunction

Author keywords

ghrelin; intestinal permeability; tight junctions; traumatic brain injury

Indexed keywords

DEXTRAN; FLUORESCEIN ISOTHIOCYANATE; GHRELIN; MYOSIN LIGHT CHAIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 78650154447     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2010.1372     Document Type: Article
Times cited : (48)

References (39)
  • 1
    • 47549114830 scopus 로고    scopus 로고
    • Effects of ghrelin on neuronal survival in cells derived from dorsal motor nucleus of the vagus
    • Ammori, J.B., Zhang, W.Z., Li, J.Y., Chai, B.X., and Mulholland, M.W. (2008). Effects of ghrelin on neuronal survival in cells derived from dorsal motor nucleus of the vagus. Surgery 144, 159-167.
    • (2008) Surgery , vol.144 , pp. 159-167
    • Ammori, J.B.1    Zhang, W.Z.2    Li, J.Y.3    Chai, B.X.4    Mulholland, M.W.5
  • 2
    • 42949124582 scopus 로고    scopus 로고
    • A critical review of the pathophysi-ology of dysautonomia following traumatic brain injury
    • Baguley, I.J., Heriseanu, R.E., Cameron, I.D., Nott, M.T., and Slewa-Younan, S. (2008). A critical review of the pathophysi-ology of dysautonomia following traumatic brain injury. Neurocrit. Care 8, 293-300.
    • (2008) Neurocrit. Care , vol.8 , pp. 293-300
    • Baguley, I.J.1    Heriseanu, R.E.2    Cameron, I.D.3    Nott, M.T.4    Slewa-Younan, S.5
  • 4
    • 77952277613 scopus 로고    scopus 로고
    • Stimulating the central nervous system to prevent intestinal dysfunction after traumatic brain injury
    • Bansal, V., Costantini, T., Ryu, S.Y., Peterson, C., Loomis, W., Putnam, J., Elicieri, B., Baird, A., and Coimbra, R. (2010). Stimulating the central nervous system to prevent intestinal dysfunction after traumatic brain injury. J. Trauma 68, 1059-1064.
    • J. Trauma , vol.68 , pp. 1059-1064
    • Bansal, V.1    Costantini, T.2    Ryu, S.Y.3    Peterson, C.4    Loomis, W.5    Putnam, J.6    Elicieri, B.7    Baird, A.8
  • 5
    • 57249103560 scopus 로고    scopus 로고
    • Challenges to the therapeutic pipeline for irritable bowel syndrome: End points and regulatory hurdles
    • Camilleri, M., and Chang, L. (2008). Challenges to the therapeutic pipeline for irritable bowel syndrome: end points and regulatory hurdles. Gastroenterology 135, 1877-1891.
    • (2008) Gastroenterology , vol.135 , pp. 1877-1891
    • Camilleri, M.1    Chang, L.2
  • 6
    • 40049104041 scopus 로고    scopus 로고
    • Progesterone administration modulates TLRs/NF-kappaB signaling pathway in rat brain after cortical contusion
    • Chen, G., Shi, J., Jin, W., Wang, L., Xie, W., Sun, J., and Hang, C. (2008). Progesterone administration modulates TLRs/NF-kappaB signaling pathway in rat brain after cortical contusion. Ann. Clin. Lab. Sci. 38, 65-74.
    • (2008) Ann. Clin. Lab. Sci. , vol.38 , pp. 65-74
    • Chen, G.1    Shi, J.2    Jin, W.3    Wang, L.4    Xie, W.5    Sun, J.6    Hang, C.7
  • 7
    • 39749191246 scopus 로고    scopus 로고
    • Glutamine decreases intestinal nuclear factor kappa B activity and pro-inflammatory cytokine expression after traumatic brain injury in rats
    • Chen, G., Shi, J., Qi, M., Yin, H., and Hang, C. (2008). Glutamine decreases intestinal nuclear factor kappa B activity and pro-inflammatory cytokine expression after traumatic brain injury in rats. Inflamm. Res. 57, 57-64.
    • (2008) Inflamm. Res. , vol.57 , pp. 57-64
    • Chen, G.1    Shi, J.2    Qi, M.3    Yin, H.4    Hang, C.5
  • 8
    • 33845910446 scopus 로고    scopus 로고
    • Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation
    • Chung, H., Kim, E., Lee, D.H., Seo, S., Ju, S., Lee, D., Kim, H., and Park, S. (2007). Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation. Endocrinology 148, 148-159.
    • (2007) Endocrinology , vol.148 , pp. 148-159
    • Chung, H.1    Kim, E.2    Lee, D.H.3    Seo, S.4    Ju, S.5    Lee, D.6    Kim, H.7    Park, S.8
  • 9
    • 59049093569 scopus 로고    scopus 로고
    • Nutrition considerations in traumatic brain injury
    • Cook, A.M., Peppard, A., and Magnuson, B. (2008). Nutrition considerations in traumatic brain injury. Nutr. Clin. Pract. 23, 608-620.
    • (2008) Nutr. Clin. Pract. , vol.23 , pp. 608-620
    • Cook, A.M.1    Peppard, A.2    Magnuson, B.3
  • 11
    • 67649195008 scopus 로고    scopus 로고
    • Pentoxifyl-line modulates intestinal tight junction signaling after burn injury: Effects on myosin light chain kinase
    • Costantini, T.W., Loomis, W.H., Putnam, J.G., Kroll, L., Eliceiri, B.P., Baird, A., Bansal, V., and Coimbra, R. (2009). Pentoxifyl-line modulates intestinal tight junction signaling after burn injury: effects on myosin light chain kinase. J. Trauma 66, 17-24.
    • (2009) J. Trauma , vol.66 , pp. 17-24
    • Costantini, T.W.1    Loomis, W.H.2    Putnam, J.G.3    Kroll, L.4    Eliceiri, B.P.5    Baird, A.6    Bansal, V.7    Coimbra, R.8
  • 14
    • 77953929950 scopus 로고    scopus 로고
    • The anti-inflammatory and neuroprotective effects of ghrelin in subarachnoid hemorrhage-induced oxidative brain damage in rats
    • Ersahin, M., Toklu, H.Z., Erzik, C., Cetinel, S., Bangir, D., Ogunc, A.V., Tetik, S., Ozdemir, Z.N., Sener, G., and Yegen, B.C. (2010). The anti-inflammatory and neuroprotective effects of ghrelin in subarachnoid hemorrhage-induced oxidative brain damage in rats. J. Neurotrauma 27, 1142-1155.
    • J. Neurotrauma , vol.27 , pp. 1142-1155
    • Ersahin, M.1    Toklu, H.Z.2    Erzik, C.3    Cetinel, S.4    Bangir, D.5    Ogunc, A.V.6    Tetik, S.7    Ozdemir, Z.N.8    Sener, G.9
  • 15
    • 38149024897 scopus 로고    scopus 로고
    • Increased intestinal permeability in rats subjected to traumatic frontal lobe percussion brain injury
    • Feighery, L., Smyth, A., Keely, S., Baird, A.W., O'Connor, W.T., Callanan, J.J., and Brayden, D.J. (2008). Increased intestinal permeability in rats subjected to traumatic frontal lobe percussion brain injury. J. Trauma 64, 131-137.
    • (2008) J. Trauma , vol.64 , pp. 131-137
    • Feighery, L.1    Smyth, A.2    Keely, S.3    Baird, A.W.4    O'Connor, W.T.5    Callanan, J.J.6    Brayden, D.J.7
  • 16
    • 33645069631 scopus 로고    scopus 로고
    • Therapeutic action of ghrelin in a mouse model of colitis
    • Gonzalez-Rey, E., Chorny, A., and Delgado, M. (2006). Therapeutic action of ghrelin in a mouse model of colitis. Gastro-enterology 130, 1707-1720.
    • (2006) Gastro-enterology , vol.130 , pp. 1707-1720
    • Gonzalez-Rey, E.1    Chorny, A.2    Delgado, M.3
  • 17
    • 33748747620 scopus 로고    scopus 로고
    • Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter
    • Graham, W.V., Wang, F., Clayburgh, D.R., Cheng, J.X., Yoon, B., Wang, Y., Lin, A., and Turner, J.R. (2006). Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter. J. Biol. Chem. 281, 26205-26215.
    • (2006) J. Biol. Chem. , vol.281 , pp. 26205-26215
    • Graham, W.V.1    Wang, F.2    Clayburgh, D.R.3    Cheng, J.X.4    Yoon, B.5    Wang, Y.6    Lin, A.7    Turner, J.R.8
  • 18
    • 79951948294 scopus 로고    scopus 로고
    • The true cost of in-patient obesity: Impact of obesity on inflammatory stress and morbidity
    • epub ahead of print
    • Grimble, R.F. (2010). The true cost of in-patient obesity: impact of obesity on inflammatory stress and morbidity. Proc. Nutr. Soc. 1-7 (epub ahead of print).
    • (2010) Proc. Nutr. Soc. , pp. 1-7
    • Grimble, R.F.1
  • 19
    • 0037423327 scopus 로고    scopus 로고
    • Obesity drug pipeline not so fat
    • Gura, T. (2003). Obesity drug pipeline not so fat. Science 299, 849-852.
    • (2003) Science , vol.299 , pp. 849-852
    • Gura, T.1
  • 20
    • 13244290283 scopus 로고    scopus 로고
    • Expressions of intestinal NF-kappaB, TNF-alpha, and IL-6 following traumatic brain injury in rats
    • Hang, C.H., Shi, J.X., Li, J.S., Li, W.Q., and Wu, W. (2005). Expressions of intestinal NF-kappaB, TNF-alpha, and IL-6 following traumatic brain injury in rats. J. Surg. Res. 123, 188-193.
    • (2005) J. Surg. Res. , vol.123 , pp. 188-193
    • Hang, C.H.1    Shi, J.X.2    Li, J.S.3    Li, W.Q.4    Wu, W.5
  • 21
    • 0347598017 scopus 로고    scopus 로고
    • Alterations of intestinal mucosa structure and barrier function following traumatic brain injury in rats
    • Hang, C.H., Shi, J.X., Li, J.S., Wu, W., and Yin, H.X. (2003). Alterations of intestinal mucosa structure and barrier function following traumatic brain injury in rats. World J. Gastro-enterol. 9, 2776-2781.
    • (2003) World J. Gastro-enterol. , vol.9 , pp. 2776-2781
    • Hang, C.H.1    Shi, J.X.2    Li, J.S.3    Wu, W.4    Yin, H.X.5
  • 23
    • 58149507594 scopus 로고    scopus 로고
    • How we die: The impact of nonneurologic organ dysfunction after severe traumatic brain injury
    • Kemp, C.D., Johnson, J.C., Riordan, W.P., and Cotton, B.A. (2008). How we die: the impact of nonneurologic organ dysfunction after severe traumatic brain injury. Am. Surg. 74, 866-872.
    • (2008) Am. Surg. , vol.74 , pp. 866-872
    • Kemp, C.D.1    Johnson, J.C.2    Riordan, W.P.3    Cotton, B.A.4
  • 24
    • 77952497875 scopus 로고    scopus 로고
    • Regulation and prognostic relevance of serum ghrelin concentrations in critical illness and sepsis
    • epub ahead of print
    • Koch, A., Sanson, E., Helm, A., Voigt, S., Trautwein, C., and Tacke, F. (2010). Regulation and prognostic relevance of serum ghrelin concentrations in critical illness and sepsis. Crit. Care 14 (epub ahead of print).
    • (2010) Crit. Care , vol.14
    • Koch, A.1    Sanson, E.2    Helm, A.3    Voigt, S.4    Trautwein, C.5    Tacke, F.6
  • 25
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima, M., Hosoda, H., Date, Y., Nakazato, M., Matsuo, H., and Kangawa, K. (1999). Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402, 656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 26
    • 36549019937 scopus 로고    scopus 로고
    • Systemic inflammation after trauma
    • Lenz, A., Franklin, G.A., and Cheadle, W.G. (2007). Systemic inflammation after trauma. Injury 38, 1336-1345.
    • (2007) Injury , vol.38 , pp. 1336-1345
    • Lenz, A.1    Franklin, G.A.2    Cheadle, W.G.3
  • 27
    • 34250205262 scopus 로고    scopus 로고
    • Ghrelin protects cortical neuron against focal ischemia/reperfusion in rats
    • Miao, Y., Xia, Q., Hou, Z., Zheng, Y., Pan, H., and Zhu, S. (2007). Ghrelin protects cortical neuron against focal ischemia/reperfusion in rats. Biochem. Biophys. Res. Commun. 359, 795-800.
    • (2007) Biochem. Biophys. Res. Commun. , vol.359 , pp. 795-800
    • Miao, Y.1    Xia, Q.2    Hou, Z.3    Zheng, Y.4    Pan, H.5    Zhu, S.6
  • 31
    • 17544375423 scopus 로고    scopus 로고
    • Experimental closed head injury: Analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines
    • Stahel, P.F., Shohami, E., Younis, F.M., Kariya, K., Otto, V.I., Lenzlinger, P.M., Grosjean, M.B., Eugster, H.P., Trentz, O., Kossmann, T., and Morganti-Kossmann, M.C. (2000). Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines. J. Cereb. Blood Flow Metab. 20, 369-380.
    • (2000) J. Cereb. Blood Flow Metab. , vol.20 , pp. 369-380
    • Stahel, P.F.1    Shohami, E.2    Younis, F.M.3    Kariya, K.4    Otto, V.I.5    Lenzlinger, P.M.6    Grosjean, M.B.7    Eugster, H.P.8    Trentz, O.9    Kossmann, T.10    Morganti-Kossmann, M.C.11
  • 32
    • 0029935286 scopus 로고    scopus 로고
    • Role of the gut in multiple organ failure: Bacterial translocation and permeability changes
    • Swank, G.M., and Deitch, E.A. (1996). Role of the gut in multiple organ failure: bacterial translocation and permeability changes. World J. Surg. 20, 411-417.
    • (1996) World J. Surg. , vol.20 , pp. 411-417
    • Swank, G.M.1    Deitch, E.A.2
  • 33
    • 33846817498 scopus 로고    scopus 로고
    • Physiology and immunology of the cholin-ergic anti-inflammatory pathway
    • Tracey, K.J. (2007). Physiology and immunology of the cholin-ergic anti-inflammatory pathway. J. Clin. Invest. 117, 289-296.
    • (2007) J. Clin. Invest. , vol.117 , pp. 289-296
    • Tracey, K.J.1
  • 34
    • 58549091080 scopus 로고    scopus 로고
    • Ghrelin and new metabolic frontiers
    • Van Der Lely, A.J. (2009). Ghrelin and new metabolic frontiers. Horm. Res. 71, Suppl 1, 129-133.
    • (2009) Horm. Res. , vol.71 , Issue.SUPPL. 1 , pp. 129-133
    • Van Der Lely, A.J.1
  • 35
    • 39149099430 scopus 로고    scopus 로고
    • Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways
    • Waseem, T., Duxbury, M., Ito, H., Ashley, S.W., and Robinson, M.K. (2008). Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways. Surgery 143, 334-342.
    • (2008) Surgery , vol.143 , pp. 334-342
    • Waseem, T.1    Duxbury, M.2    Ito, H.3    Ashley, S.W.4    Robinson, M.K.5
  • 37
    • 34247640178 scopus 로고    scopus 로고
    • Ghrelin down-regulates proin-flammatory cytokines in sepsis through activation of the vagus nerve
    • Wu, R., Dong, W., Cui, X., Zhou, M., Simms, H.H., Ravikumar, T.S., and Wang, P. (2007). Ghrelin down-regulates proin-flammatory cytokines in sepsis through activation of the vagus nerve. Ann. Surg. 245, 480-486.
    • (2007) Ann. Surg. , vol.245 , pp. 480-486
    • Wu, R.1    Dong, W.2    Cui, X.3    Zhou, M.4    Simms, H.H.5    Ravikumar, T.S.6    Wang, P.7
  • 38
    • 68249101621 scopus 로고    scopus 로고
    • Orexigenic hormone ghrelin ameliorates gut barrier dysfunction in sepsis in rats
    • Wu, R., Dong, W., Qiang, X., Wang, H., Blau, S.A., Ravikumar, T.S., and Wang, P (2009). Orexigenic hormone ghrelin ameliorates gut barrier dysfunction in sepsis in rats. Crit. Care Med. 37, 2421-2426.
    • (2009) Crit. Care Med. , vol.37 , pp. 2421-2426
    • Wu, R.1    Dong, W.2    Qiang, X.3    Wang, H.4    Blau, S.A.5    Ravikumar, T.S.6    Wang, P.7
  • 39


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.