Overexpression and gender-specific differences of SRC-3 (SRC-3/AIB1) immunoreactivity in human non-small cell lung cancer: An in vivo study

Journal of Histochemistry and Cytochemistry

Volumn 58, Issue 12, 2010, Pages 1121-1127

  Wang, Haidong ^a   Zhang, Dongmei ^a   Wu, Wei ^a   Zhang, Jiqiang ^a   Guo, Deyu ^a   Wang, Qingliang ^a   Jing, Tao ^a   Xu, Chengping ^a   Bian, Xiuwu ^a   Yang, Kang ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Endocrine cancer; Immunohistochemistry; Non small cell lung cancer; Steroid; Steroid receptor coactivator 3; Tissue microarray

Indexed keywords

NICKEL; STEROID RECEPTOR COACTIVATOR 3;

ADULT; AGED; ARTICLE; FEMALE; GENDER; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MALE; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEX DIFFERENCE; TISSUE MICROARRAY;

ADULT; AGED; CARCINOMA, NON-SMALL-CELL LUNG; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MIDDLE AGED; NUCLEAR RECEPTOR COACTIVATOR 3; SEX CHARACTERISTICS; TISSUE ARRAY ANALYSIS;

EID: 78650153769     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.2010.956979     Document Type: Article

References (39)

1. Ali G, Donati V, Loggini B, Servadio A, Dell'Omodarme M, Prati MC, Camacci T, et al. (2008) Different estrogen receptor beta expression in distinct histologic subtypes of lung adenocarcinoma. Hum Pathol 39:1465-1473
2. Anzick SL, Kononen J, Walker RL, Azorsa DO, Tanner MM, Guan XY, Sauter G, et al. (1997) AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science 277:965-968 (Pubitemid 27366683)
3. Balmer NN, Richer JK, Spoelstra NS, Torkko KC, Lyle PL, Singh M (2006) Steroid receptor coactivator AIB1 in endometrial carcinoma, hyperplasia and normal endometrium: correlation with clinicopathologic parameters and biomarkers. Mod Pathol 19:1593-1605 (Pubitemid 44789928)
4. Bautista S, Valles H, Walker RL, Anzick S, Zeillinger R, Meltzer P, Theillet C (1998) In breast cancer, amplification of the steroid receptor coactivator gene AIB1 is correlated with estrogen and progesterone receptor positivity. Clin Cancer Res 4:2925-2929
5. Dougherty SM, Mazhawidza W, Bohn AR, Robinson KA, Mattingly KA, Blankenship KA, Huff MO, et al. (2006) Gender difference in the activity but not expression of estrogen receptors alpha and beta in human lung adenocarcinoma cells. Endocr Relat Cancer 13:113-134
6. Grenier J, Trousson A, Chauchereau A, Amazit L, Lamirand A, Leclerc P, Guiochon-Mantel A, et al. (2004) Selective recruitment of p160 coactivators on glucocorticoid-regulated promoters in Schwann cells. Mol Endocrinol 18:2866-2879 (Pubitemid 39577912)
7. Harichand-Herdt S, Ramalingam SS (2009) Gender-associated differences in lung cancer: clinical characteristics and treatment outcomes in women. Semin Oncol 36:572-580
8. Henke RT, Haddad BR, Kim SE, Rone JD, Mani A, Jessup JM, Wellstein A, et al. (2004) Overexpression of the nuclear receptor coactivator AIB1 (SRC-3) during progression of pancreatic adenocarcinoma. Clin Cancer Res 10:6134-6142 (Pubitemid 39287519)
9. Hershberger PA, Stabile LP, Kanterewicz B, Rothstein ME, Gubish CT, Land S, Shuai Y, et al. (2009) Estrogen receptor beta (ERbeta) subtype-specific ligands increase transcription, p44/p42 mitogen activated protein kinase (MAPK) activation and growth in human non-small cell lung cancer cells. J Steroid Biochem Mol Biol 116: 102-109
10. Hong H, Kohli K, Trivedi A, Johnson DL, Stallcup MR (1996) GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors. Proc Natl Acad Sci USA 93:4948-4952 (Pubitemid 26163504)
11. Ishibashi H, Suzuki T, Suzuki S, Niikawa H, Lu L, Miki Y, Moriya T, et al. (2005) Progesterone receptor in non-small cell lung cancer: a potent prognostic factor and possible target for endocrine therapy. Cancer Res 65:6450-6458 (Pubitemid 40994434)
12. Kuang SQ, Liao L, Wang S, Medina D, O'Malley BW, Xu J (2005) Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis. Cancer Res 65:7993-8002 (Pubitemid 41297279)
13. Kuang SQ, Liao L, Zhang H, Lee AV, O'Malley BW, Xu J (2004) AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice. Cancer Res 64:1875-1885 (Pubitemid 38428714)
14. Li P, Zhang Z, Wang Q, Li S, Zhang Y, Bian X, Chen A, et al. (2009) The ectopic expression of IFN regulatory factor 4-binding protein is correlated with the malignant behavior of human breast cancer cells. Int Immunopharmacol 9:1002-1009
15. Louie MC, Zou JX, Rabinovich A, Chen HW (2004) ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance. Mol Cell Biol 24: 5157-5171 (Pubitemid 38738153)
16. Lu YS, Lien HC, Yeh PY, Kuo SH, Chang WC, Kuo ML, Cheng AL (2006) Glucocorticoid receptor expression in advanced non-small cell lung cancer: clinicopathological correlation and in vitro effect of glucocorticoid on cell growth and chemosensitivity. Lung Cancer 53:303-310
17. Marquez-Garban DC, Chen HW, Fishbein MC, Goodglick L, Pietras RJ (2007) Estrogen receptor signaling pathways in human nonsmall cell lung cancer. Steroids 72:135-143 (Pubitemid 46273500)
18. Nose N, Sugio K, Oyama T, Nozoe T, Uramoto H, Iwata T, Onitsuka T, et al. (2009) Association between estrogen receptor-beta expression and epidermal growth factor receptor mutation in the postoperative prognosis of adenocarcinoma of the lung. J Clin Oncol 27:411-417
19. Onate SA, Tsai SY, Tsai MJ, O'Malley BW (1995) Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354-1357
20. Raso MG, Behrens C, Herynk MH, Liu S, Prudkin L, Ozburn NC, Woods DM, et al. (2009) Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation. Clin Cancer Res 15:5359-5368
21. Sakaguchi H, Fujimoto J, Sun WS, Tamaya T (2007) Clinical implications of steroid receptor coactivator (SRC)-3 in uterine endometrial cancers. J Steroid Biochem Mol Biol 104:237-240 (Pubitemid 46891818)
22. Sommer P, Le Rouzic P, Gillingham H, Berry A, Kayahara M, Huynh T, White A, et al. (2007) Glucocorticoid receptor overexpression exerts an antisurvival effect on human small cell lung cancer cells. Oncogene 26:7111-7121 (Pubitemid 350064190)
23. Stabile LP, Siegfried JM (2003) Sex and gender differences in lung cancer. J Gend Specif Med 6:37-48 (Pubitemid 36410481)
24. Suen CS, Berrodin TJ, Mastroeni R, Cheskis BJ, Lyttle CR, Frail DE (1998) A transcriptional coactivator, steroid receptor coactivator-3, selectively augments steroid receptor transcriptional activity. J Biol Chem 273:27645-27653 (Pubitemid 28500489)
25. Tanner MM, Grenman S, Koul A, Johannsson O, Meltzer P, Pejovic T, Borg A, et al. (2000) Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer. Clin Cancer Res 6:1833-1839 (Pubitemid 30305079)
26. Tien JC, Zhou S, Xu J (2009) The role of SRC-1 in murine prostate cancinogenesis is nonessential due to a possible compensation of SRC-3/AIB1 overexpression. Int J Biol Sci 5:256-264
27. Torres-Arzayus MI, Font de Mora J, Yuan J, Vazquez F, Bronson R, Rue M, Sellers WR, et al. (2004) High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene. Cancer Cell 6:263-274 (Pubitemid 39222039)
28. Travis WD, Brambilla E, Müller-Hermelink HK, Harris CC, eds. (2004) Pathology and genetics of tumours of the lung, pleura, thymus and heart. Lyon, IARC
29. Voegel JJ, Heine MJ, Zechel C, Chambon P, Gronemeyer H (1996) TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors. EMBO J 15:3667-3675 (Pubitemid 26239779)
30. Waters CE, Stevens A, White A, Ray DW (2004) Analysis of co-factor function in a glucocorticoid-resistant small cell carcinoma cell line. J Endocrinol 183:375-383 (Pubitemid 39562717)
31. Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, et al. (2002) Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) coactivator activity by I kappa B kinase. Mol Cell Biol 22:3549-3561 (Pubitemid 34453993)
32. Xu J, Li Q (2003) Review of the in vivo functions of the p160 steroid receptor coactivator family. Mol Endocrinol 17:1681-1692 (Pubitemid 37072287)
33. Yan J, Erdem H, Li R, Cai Y, Ayala G, Ittmann M, Yu-Lee LY, et al. (2008) Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression. Cancer Res 68:5460-5468
34. Yan J, Tsai SY, Tsai MJ (2006a) SRC-3/AIB1: transcriptional coactivator in oncogenesis. Acta Pharmacol Sin 27:387-394
35. Yan J, Yu CT, Ozen M, Ittmann M, Tsai SY, Tsai MJ (2006b) Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway. Cancer Res 66:11039-11046 (Pubitemid 44877004)
36. Ying H, Willingham MC, Cheng SY (2008) The steroid receptor coactivator-3 is a tumor promoter in a mouse model of thyroid cancer. Oncogene 27:823-830 (Pubitemid 351186318)
37. Yu C, York B, Wang S, Feng Q, Xu J, O'Malley BW (2007) An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response. Mol Cell 25:765-778 (Pubitemid 46341916)
38. Zhang G, Liu X, Farkas AM, Parwani AV, Lathrop KL, Lenzner D, Land SR, et al. (2009) Estrogen receptor beta functions through nongenomic mechanisms in lung cancer cells. Mol Endocrinol 23:146-156
39. Zhang JQ, Cai WQ, Zhou DS, Su BY (2002) Distribution and differences of estrogen receptor beta immunoreactivity in the brain of adult male and female rats. Brain Res 935:73-80