메뉴 건너뛰기




Volumn 15, Issue 10, 2010, Pages 1204-1210

A disease-relevant high-content screening assay to identify anti-inflammatory compounds for Use in cystic fibrosis

Author keywords

CFTR; cystic fibrosis; HCS; HTS; inflammation; NF B

Indexed keywords

ALCOHOL; ANTIINFLAMMATORY AGENT; BECLOMETASONE; CEFIXIME; DELTA1 HYDROCORTISONE 21; DESOXIMETASONE; DIMETHYL SULFOXIDE; FLUTICASONE PROPIONATE; HALOMETASONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IRBESARTAN; LOTEPREDNOL ETABONATE; MEDROXYPROGESTERONE; MEGESTROL ACETATE; MLS 000758292; TACROLIMUS; UNCLASSIFIED DRUG;

EID: 78650146676     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057110384612     Document Type: Article
Times cited : (9)

References (27)
  • 3
    • 33745120825 scopus 로고    scopus 로고
    • CFTR chloride channel drug discovery: Inhibitors as antidiarrheals and activators for therapy of cystic fibrosis
    • Verkman AS, Lukacs GL, Galietta LJ: CFTR chloride channel drug discovery: inhibitors as antidiarrheals and activators for therapy of cystic fibrosis. Curr Pharm Des 2006 ; 12: 2235-2247.
    • (2006) Curr Pharm des , vol.12 , pp. 2235-2247
    • Verkman, A.S.1    Lukacs, G.L.2    Galietta, L.J.3
  • 4
    • 15344345842 scopus 로고    scopus 로고
    • Cystic fibrosis: An overview
    • Turcios NL: Cystic fibrosis: an overview. J Clin Gastroenterol 2005 ; 39: 307-317.
    • (2005) J Clin Gastroenterol , vol.39 , pp. 307-317
    • Turcios, N.L.1
  • 5
    • 22544487504 scopus 로고    scopus 로고
    • Physiotherapy management of cystic fibrosis
    • Dodd ME, Prasad SA: Physiotherapy management of cystic fibrosis. Chron Respir Dis 2005 ; 2: 139-149.
    • (2005) Chron Respir Dis , vol.2 , pp. 139-149
    • Dodd, M.E.1    Prasad, S.A.2
  • 6
    • 27744459408 scopus 로고    scopus 로고
    • Human airway epithelial cells sense Pseudomonas aeruginosa infection via recognition of flagellin by Toll-like receptor 5
    • Zhang Z., Louboutin JP, Weiner DJ, Goldberg JB, Wilson JM: Human airway epithelial cells sense Pseudomonas aeruginosa infection via recognition of flagellin by Toll-like receptor 5. Infect Immun 2005 ; 73: 7151-7160.
    • (2005) Infect Immun , vol.73 , pp. 7151-7160
    • Zhang, Z.1    Louboutin, J.P.2    Weiner, D.J.3    Goldberg, J.B.4    Wilson, J.M.5
  • 7
    • 25444452653 scopus 로고    scopus 로고
    • Airway epithelial cell tolerance to Pseudomonas aeruginosa
    • Wu Q., Lu Z., Verghese MW, Randell SH: Airway epithelial cell tolerance to Pseudomonas aeruginosa. Respir Res 2005 ; 6: 26.
    • (2005) Respir Res , vol.6 , pp. 26
    • Wu, Q.1    Lu, Z.2    Verghese, M.W.3    Randell, S.H.4
  • 8
    • 70349303073 scopus 로고    scopus 로고
    • Role of CFTR, Pseudomonas aeruginosa and Toll-like receptors in cystic fibrosis lung inflammation
    • Buchanan PJ, Ernst RK, Elborn JS, Schock B.: Role of CFTR, Pseudomonas aeruginosa and Toll-like receptors in cystic fibrosis lung inflammation. Biochem Soc Trans 2009 ; 37: 863-867.
    • (2009) Biochem Soc Trans , vol.37 , pp. 863-867
    • Buchanan, P.J.1    Ernst, R.K.2    Elborn, J.S.3    Schock, B.4
  • 9
    • 0032817772 scopus 로고    scopus 로고
    • Altered respiratory epithelial cell cytokine production in cystic fibrosis
    • Bonfield TL, Konstan MW, Berger M.: Altered respiratory epithelial cell cytokine production in cystic fibrosis. J Allergy Clin Immunol 1999 ; 104: 72-78.
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 72-78
    • Bonfield, T.L.1    Konstan, M.W.2    Berger, M.3
  • 10
    • 0142043977 scopus 로고    scopus 로고
    • Pathophysiology and management of pulmonary infections in cystic fibrosis
    • Gibson RL, Burns JL, Ramsey BW: Pathophysiology and management of pulmonary infections in cystic fibrosis. Am J Respir Crit Care Med 2003 ; 168: 918-951.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 918-951
    • Gibson, R.L.1    Burns, J.L.2    Ramsey, B.W.3
  • 11
    • 0034704799 scopus 로고    scopus 로고
    • Risk of persistent growth impairment after alternate-day prednisone treatment in children with cystic fibrosis
    • Lai HC, FitzSimmons SC, Allen DB, Kosorok MR, Rosenstein BJ, Campbell PW,, et al. Risk of persistent growth impairment after alternate-day prednisone treatment in children with cystic fibrosis. N Engl J Med 2000 ; 342: 851-859.
    • (2000) N Engl J Med , vol.342 , pp. 851-859
    • Lai, H.C.1    Fitzsimmons, S.C.2    Allen, D.B.3    Kosorok, M.R.4    Rosenstein, B.J.5    Campbell, P.W.6
  • 12
    • 0028914667 scopus 로고
    • Effect of high-dose ibuprofen in patients with cystic fibrosis
    • Konstan MW, Byard PJ, Hoppel CL, Davis PB: Effect of high-dose ibuprofen in patients with cystic fibrosis. N Engl J Med 1995 ; 332: 848-854.
    • (1995) N Engl J Med , vol.332 , pp. 848-854
    • Konstan, M.W.1    Byard, P.J.2    Hoppel, C.L.3    Davis, P.B.4
  • 13
    • 33646143775 scopus 로고    scopus 로고
    • Acute Pseudomonas challenge in cystic fibrosis mice causes prolonged nuclear factor-kappa B activation, cytokine secretion, and persistent lung inflammation
    • Saadane A., Soltys J., Berger M.: Acute Pseudomonas challenge in cystic fibrosis mice causes prolonged nuclear factor-kappa B activation, cytokine secretion, and persistent lung inflammation. J Allergy Clin Immunol 2006 ; 117: 1163-1169.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 1163-1169
    • Saadane, A.1    Soltys, J.2    Berger, M.3
  • 14
    • 0038266174 scopus 로고    scopus 로고
    • The role of nuclear factor kappa B in the pathogenesis of pulmonary diseases: Implications for therapy
    • Wright JG, Christman JW: The role of nuclear factor kappa B in the pathogenesis of pulmonary diseases: implications for therapy. Am J Respir Med 2003 ; 2: 211-219.
    • (2003) Am J Respir Med , vol.2 , pp. 211-219
    • Wright, J.G.1    Christman, J.W.2
  • 15
    • 16344381319 scopus 로고    scopus 로고
    • Antiinflammatory therapies for cystic fibrosis: Past, present, and future
    • Prescott WA Jr, Johnson CE: Antiinflammatory therapies for cystic fibrosis: past, present, and future. Pharmacotherapy 2005 ; 25: 555-573.
    • (2005) Pharmacotherapy , vol.25 , pp. 555-573
    • Prescott Jr., W.A.1    Johnson, C.E.2
  • 17
    • 67651171596 scopus 로고    scopus 로고
    • Inhibition of NFkappaB by the natural product Withaferin A in cellular models of cystic fibrosis inflammation
    • Lond)
    • Maitra R., Porter MA, Huang S., Gilmour BP: Inhibition of NFkappaB by the natural product Withaferin A in cellular models of cystic fibrosis inflammation. J Inflamm (Lond) 2009 ; 6: 15.
    • (2009) J Inflamm , vol.6 , pp. 15
    • Maitra, R.1    Porter, M.A.2    Huang, S.3    Gilmour, B.P.4
  • 19
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • Zhang JH, Chung TD, Oldenburg KR: A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 1999 ; 4: 67-73.
    • (1999) J Biomol Screen , vol.4 , pp. 67-73
    • Zhang, J.H.1    Chung, T.D.2    Oldenburg, K.R.3
  • 21
    • 12444322678 scopus 로고    scopus 로고
    • TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells
    • Greene CM, Carroll TP, Smith SG, Taggart CC, Devaney J., Griffin S.,, et al. TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells. J Immunol 2005 ; 174: 1638-1646.
    • (2005) J Immunol , vol.174 , pp. 1638-1646
    • Greene, C.M.1    Carroll, T.P.2    Smith, S.G.3    Taggart, C.C.4    Devaney, J.5    Griffin, S.6
  • 23
    • 23644462552 scopus 로고    scopus 로고
    • Cystic fibrosis lung disease: Genetic influences, microbial interactions, and radiological assessment
    • Moskowitz SM, Gibson RL, Effmann EL: Cystic fibrosis lung disease: genetic influences, microbial interactions, and radiological assessment. Pediatr Radiol 2005 ; 35: 739-757.
    • (2005) Pediatr Radiol , vol.35 , pp. 739-757
    • Moskowitz, S.M.1    Gibson, R.L.2    Effmann, E.L.3
  • 24
    • 0034128090 scopus 로고    scopus 로고
    • The role of nuclear factor-kappa B in pulmonary diseases
    • Christman JW, Sadikot RT, Blackwell TS: The role of nuclear factor-kappa B in pulmonary diseases. Chest 2000 ; 117: 1482-1487.
    • (2000) Chest , vol.117 , pp. 1482-1487
    • Christman, J.W.1    Sadikot, R.T.2    Blackwell, T.S.3
  • 26
    • 0034920401 scopus 로고    scopus 로고
    • Anti-inflammatory approaches to the treatment of cystic fibrosis lung disease: Past, present and future
    • Oermann CM: Anti-inflammatory approaches to the treatment of cystic fibrosis lung disease: past, present and future. Curr Opin Investig Drugs 2001 ; 2: 900-906.
    • (2001) Curr Opin Investig Drugs , vol.2 , pp. 900-906
    • Oermann, C.M.1
  • 27
    • 36348933409 scopus 로고    scopus 로고
    • Appetite stimulants in cystic fibrosis: A systematic review
    • Chinuck RS, Fortnum H., Baldwin DR: Appetite stimulants in cystic fibrosis: a systematic review. J Hum Nutr Diet 2007 ; 20: 526-537.
    • (2007) J Hum Nutr Diet , vol.20 , pp. 526-537
    • Chinuck, R.S.1    Fortnum, H.2    Baldwin, D.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.