Distribution of genes encoding virulence factors ompB2, ompCD, ompE, β-lactamase and serotype in pathogenic and colonizing strains of Moraxella catarrhalis

Archives of Medical Research

Volumn 41, Issue 7, 2010, Pages 530-535

  Mitov, Ivan G ^a   Gergova, Raina T ^a   Ouzounova Raykova, Vessela V ^a  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

Author keywords

lactamase; Lipooligosaccharide; Moraxella catarrhalis; Serotype; Virulence

Indexed keywords

BETA LACTAMASE; LIPOOLIGOSACCHARIDE; MONOCLONAL ANTIBODY; VIRULENCE FACTOR;

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; GENE CONTROL; GENE FREQUENCY; HETEROZYGOTE; HUMAN; IRON TRANSPORT; MAJOR CLINICAL STUDY; MORAXELLA CATARRHALIS; NONHUMAN; OTORHINOLARYNGOLOGY; POLYMERASE CHAIN REACTION; RESPIRATORY TRACT INFECTION; SEROTYPING;

ADHESINS, BACTERIAL; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL TRANSFERRIN RECEPTOR COMPLEX; BETA-LACTAMASES; CARRIER STATE; CHILD; CHILD, PRESCHOOL; FEMALE; GENE FREQUENCY; HUMANS; INFANT; MALE; MIDDLE AGED; MORAXELLA (BRANHAMELLA) CATARRHALIS; MORAXELLACEAE INFECTIONS; RESPIRATORY TRACT INFECTIONS; SEROTYPING; VIRULENCE FACTORS; YOUNG ADULT;

EID: 78650132957     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2010.10.003     Document Type: Article

References (50)

1. Enright M.C., McKenzie H. Moraxella (Branhamella) catarrhalis-clinical and molecular aspects of a rediscovered pathogen. J Med Microbiol 1997, 46:360-371.
2. Sethi S., Sethi R., Eschberger K., et al. Airway bacterial concentrations and exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007, 176:356-361.
3. Tellez I., Duran L.M.A., Reyes M.G., et al. Microbiology of acute sinusitis in Mexican patients. Arch Med Res 2006, 37:395-398.
4. Verduin C.M., Hol C., Fleer A., et al. Moraxella catarrhalis: from emerging to established pathogen. Clin Microbiol Rev 2002, 15:125-144.
5. Hays J.P. Moraxella catarrhalis: a mini review. J Pediatr Infect Dis 2009, 4:211-220.
6. Murphy T.F., Brauer A.L., Yuskiw N., et al. Antigenic structure of outer membrane protein E of Moraxella catarrhalis and construction and characterization of mutants. Infect Immun 2000, 68:6250-6256.
7. Timpe J.M., Holm M.M., Vanlerberg S.L., et al. Identification of a Moraxella catarrhalis outer membrane protein exhibiting both adhesin and lipolytic activities. Infect Immun 2003, 71:4341-4350.
8. Wirth T., Morelli G., Kusecek B., et al. The rise and spread of a new pathogen: seroresistant Moraxella catarrhalis. Genome Res 2007, 17:1647-1656.
9. de Vries S.P.W., Bootsma H.J., Hays J.P., et al. Molecular aspects of Moraxella catarrhalis pathogenesis. Microbiol Mol Biol Rev 2009, 73:389-406.
10. Aebi C., Maciver I., Latimer J.L., et al. A protective epitope of Moraxella catarrhalis is encoded by two different genes. Infect Immun 1997, 65:4367-4377.
11. Helminen M.E., Maciver I., Latimer J.L., et al. A major outer membrane protein of Moraxella catarrhalis is a target for antibodies that enhance pulmonary clearance of the pathogen in an animal model. Infect Immun 1993, 61:2003-2010.
12. Reddy M.S., Murphy T.F., Faden H.S., et al. Middle ear mucin glycoprotein: purification and interaction with nontypable Haemophilus influenzae and Moraxella catarrhalis. Otolaryngol Head Neck Surg 1997, 116:175-180.
13. Zaleski A., Scheffler N.K., Densen P., et al. Lipooligosaccharide P(k) (Galalpha1-4Galbeta1-4Glc) epitope of Moraxella catarrhalis is a factor in resistance to bactericidal activity mediated by normal human serum. Infect Immun 2000, 68:5261-5268.
14. Furano K., Campagnari A.A. Inactivation of the Moraxella catarrhalis 7169 ferric uptake regulator increases susceptibility to the bactericidal activity of normal human sera. Infect Immun 2003, 71:1843-1848.
15. Aebi C., Stone B., Beucher M., et al. Expression of the CopB outer membrane protein by Moraxella catarrhalis is regulated by iron and affects iron acquisition from transferrin and lactoferrin. Infect Immun 1996, 64:2024-2030.
16. Campagnari A.A., Ducey T.F., Rebmann C.A. Outer membrane protein Bl, an iron-repressible protein conserved in the outer membrane of Moraxella (Branhamella) catarrhalis, binds human transferrin. Infect Immun 1996, 64:3920-3924.
17. McGregor K., Chang B.J., Mee B.J., et al. Moraxella catarrhalis: clinical significance, antimicrobial susceptibility and BRO beta-lactamases. Eur J Clin Microbiol Infect Dis 1998, 17:219-234.
18. Gergova R.T., Markovska R., Mitov I.G. Antimicrobial resistance and production of beta-lactamases in Bulgarian clinical isolates Moraxella catarrhalis. Ann Microbiol 2009, 59:169-172.
19. Hsueh P.R., Liu Y.C., Shyr J.M., et al. Multicenter surveillance of antimicrobial resistance of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in Taiwan during the 1998-1999 respiratory season. Antimicrob Agents Chemother 2000, 44:1342-1345.
20. Schmitz F.J., Beeck A., Perdikouli M., et al. Production of BRO beta-lactamases and resistance to complement in European Moraxella catarrhalis isolates. J Clin Microbiol 2002, 40:1546-1548.
21. Budhani R.K., Struthers J.K. Interaction of Streptococcus pneumoniae and Moraxella catarrhalis: investigation of the indirect pathogenic role of β-lactamase-P producing Moraxellae by use of a continuous-culture biofilm system. Antimicrob Agents Chemother 1998, 42:2521-2526.
22. Lafontaine E.R., Wall D., Vanlerberg S.L., et al. Moraxella catarrhalis coaggregates with Streptococcus pyogenes and modulates interactions of S. pyogenes with human epithelial cells. Infect Immun 2004, 72:6689-6693.
23. Carville K.S., Bowman J.M., Lehmann D., et al. Comparison between nasal swabs and nasopharyngeal aspirates for, and effect of time in transit on, isolation of Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, and Moraxella catarrhalis. J Clin Microbiol 2007, 45:244-245.
24. Lieberman D., Shimoni A., Terry A., et al. Mixing of nasopharyngeal and oropharyngeal samples to identify potential respiratory pathogens in adults. Eur J Clin Microbiol Infect Dis 2007, 26:591-593.
25. Gergova R.T., Iankov I.D., Haralambieva I.H., et al. Bactericidal monoclonal antibody against Moraxella catarrhalis lipooligosaccharide cross-reacts with Haemophilus spp. Curr Microbiol 2007, 54:85-90.
26. Bootsma H.J., Van Der Heide H.G.J., Van De Pas S., et al. Analysis of Moraxella catarrhalis by DNA typing: evidence for a distinct subpopulation associated with virulence traits. J Infect Dis 2000, 181:1376-1387.
27. Levy F., Walker E.S. BRO beta-lactamase alleles, antibiotic resistance and a test of the BRO-1 selective replacement hypothesis in Moraxella catarrhalis. J Antimicrob Chemother 2004, 53:371-374.
28. Holm M.M., Vanlerberg S.L., Foley I.M., et al. The Moraxella catarrhalis porin-like outer membrane protein CD is an adhesin for human lung cells. Infect Immun 2004, 72:1906-1913.
29. Sethi S., Murphy T.F. Bacterial infection in chronic obstructive pulmonary disease in 2000: a state-of-the-art review. Clin Microbiol Rev 2001, 336-363.
30. Bernstein J.M.L., Reddy M. Bacteria-mucin interaction in the upper aerodigestive tract shows striking heterogeneity: implications in otitis media, rhinosinusitis, and pneumonia. Otolaryngol Head Neck Surg 2000, 122:514-520.
31. Karalus R., Campagnari A. Moraxella catarrhalis: a review of an important human mucosal pathogen. Microbes Infect 2000, 5:547-559.
32. Murphy T.F., Kirkham C., DeNardin E., et al. Analysis of antigenic structure and human immune response to outer membrane protein CD of Moraxella catarrhalis. Infect Immun 1999, 67:4578-4585.
33. Kyd J., John A., Cripps A., et al. Investigation of mucosal immunisation in pulmonary clearance of Moraxella (Branhamella) catarrhalis. Vaccine 1999, 18:398-406.
34. Murphy T.F., Kyd J.M., John A., et al. Cripps AW Enhancement of pulmonary clearance of Moraxella (Branhamella) catarrhalis following immunization with outer membrane protein CD in a mouse model. J Infect Dis 1998, 178:1667-1675.
35. Yang Y.P., Myers L.E., McGuinness U., et al. The major outer membrane protein, CD, extracted from Moraxella (Branhamella) catarrhalis is a potential vaccine antigen that induces bactericidal antibodies. FEMS Immunol Med Microbiol 1997, 17:187-199.
36. Murphy T.F., Brauer A.L., Yuskiw N., et al. Conservation of outer membrane protein E among strains of Moraxella catarrhalis. Infect Immun 2001, 69:3576-3580.
37. Bhushan R., Kirkham C., Sethi S., et al. Antigenic characterization and analysis of the human immune response to outer membrane protein E of Branhamella catarrhalis. Infect Immun 1997, 65:2668-2675.
38. Tan T.T., Riesbeck K. Current progress of adhesins as vaccine candidates for Moraxella catarrhalis. Exp Rev Vaccines 2007, 6:949-956.
39. Myers L.E., Yang Y.P., Du R.P., et al. The transferrin binding protein B of Moraxella catarrhalis elicits bactericidal antibodies and is a potential vaccine antigen. Infect Immun 1998, 66:4183-4192.
40. Sethi S., Surface J.M., Murphy T.F. Antigenic heterogeneity and molecular analysis of CopB of Moraxella (Branhamella) catarrhalis. Infect Immun 1997, 65:3666-3671.
41. Liu D.F., Xie X., Mastri M.G., et al. Polymorphism of the major surface epitope of the CopB outer membrane protein of Moraxella catarrhalis. FEMS Immunol Med Microbiol 2006, 47:343-350.
42. Estabrook M.M., Jack D.L., Klein N.J., et al. Mannose-binding lectin binds to two major outer membrane proteins, opacity protein and porin, of Neisseria meningitidis. J Immunol 2004, 1720:3784-3792.
43. Estabrook M.M., Jarvis G.A., Griffiss J.M. Affinity purified human IgG that binds a lacto-N-neotetraose-dependent lipooligosaccharide structure is bactericidal for serogroup B Neisseria meningitidis. Infect Immun 2007, 75:1025-1033.
44. Madico G., Welsch J.A., Lewis L.A., et al. The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance. J Immunol 2006, 1(177):501-510.
45. Mawas F., Ho M.M., Corbel M.J., et al. Current progress with Moraxella catarrhalis antigens as vaccine candidates. Exp Rev Vaccines 2009, 8:77-90.
46. Slevogt H., Tiwari K.N., Schmeck B., et al. Adhesion of Moraxella catarrhalis to human bronchial epithelium characterized by a novel fluorescence-based assay. Med Microbiol Immunol 2006, 195:73-83.
47. Slevogt H., Seybold J., Tiwari K.N., et al. Moraxella catarrhalis is internalized in respiratory epithelial cells by a trigger-like mechanism and initiates a TLR2- and partly NOD1-dependent inflammatory immune response. Cell Microbiol 2007, 9:694-707.
48. Hall-Stoodley L., Hu F.Z., Gieseke A., et al. Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media. JAMA 2006, 296:202-211.
49. Koseoglu O., Ergin A., Gurkan Aydin N., et al. Molecular characterization of BRO beta-lactamases of Moraxella catarrhalis strains isolated from carrier children. Mikrobiyol Bul 2004, 38:335-340.
50. Verhaegh S.J.C., Streefland A., Dewnarain J.K., et al. Age-related genotypic and phenotypic differences in Moraxella catarrhalis isolates from children and adults presenting with respiratory disease in 2001-2002. Microbiology 2008, 154:1178-1184.