Relationships linking amplification level to gene over-expression in gliomas

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Vogt, Nicolas ^a,b,c   Gibaud, Anne ^a,b,c   Almeida, Anna ^a,b,c   Ourliac Garnier, Isabelle ^a,b,c   Debatisse, Michelle ^a,b,c   Malfoy, Bernard ^a,b,c  

^a INSTITUT CURIE   (France)

^b Institut Curie   (France)

^c SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; EXTRACHROMOSOMAL DNA; MESSENGER RNA; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; TELOMERASE;

AMPLICON; ARTICLE; CELL TYPE; CONTROLLED STUDY; DNA SEQUENCE; GENE ACTIVITY; GENE AMPLIFICATION; GENE DOSAGE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GLIOMA; HUMAN; HUMAN TISSUE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSLATION; TISSUE SPECIFICITY; TUMOR GROWTH; TUMOR XENOGRAFT; BRAIN TUMOR; CANCER TRANSPLANTATION; DISEASE COURSE; GENE EXPRESSION REGULATION; GENETICS; GLIOBLASTOMA; METABOLISM; OLIGODENDROGLIOMA; PROTEIN PROCESSING;

BRAIN NEOPLASMS; DISEASE PROGRESSION; DNA; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GLIOBLASTOMA; GLIOMA; HUMANS; NEOPLASM TRANSPLANTATION; OLIGODENDROGLIOMA; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR, EPIDERMAL GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TELOMERASE;

EID: 78650110592     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014249     Document Type: Article

References (37)

1. Myllykangas S, Bohling T, Knuutila S (2007) Specificity, selection and significance of gene amplifications in cancer. Semin Cancer Biol 17: 42-55.
2. Santarius T, Shipley J, Brewer D, Stratton MR, Cooper CS (2010) A census of amplified and overexpressed human cancer genes. Nat Rev Cancer 10: 59-64.
3. Debatisse M, Malfoy B (2005) Gene amplification mechanisms. In: Nigg EA, ed. Genome instability in cancer development: Springer. pp 343-362.
4. Albertson DG (2006) Gene amplification in cancer. Trends Genet 22: 447-455.
5. Garcia MJ, Pole JC, Chin SF, Teschendorff A, Naderi A, et al. (2005) A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes. Oncogene 24: 5235-5245.
6. Gelsi-Boyer V, Orsetti B, Cervera N, Finetti P, Sircoulomb F, et al. (2005) Comprehensive profiling of 8p11-12 amplification in breast cancer. Mol Cancer Res 3: 655-667.
7. Huang X, Godfrey TE, Gooding WE, McCarty KS, Jr., Gollin SM (2006) Comprehensive genome and transcriptome analysis of the 11q13 amplicon in human oral cancer and synteny to the 7F5 amplicon in murine oral carcinoma. Genes Chromosomes Cancer 45: 1058-1069.
8. Kao J, Pollack JR (2006) RNA interference-based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes. Genes Chromosomes Cancer 45: 761-769.
9. Parssinen J, Kuukasjarvi T, Karhu R, Kallioniemi A (2007) High-level amplification at 17q23 leads to coordinated overexpression of multiple adjacent genes in breast cancer. Br J Cancer 96: 1258-1264.
10. Bralten LB, Kloosterhof NK, Gravendeel LA, Sacchetti A, Duijm EJ, et al. (2010) Integrated genomic profiling identifies candidate genes implicated in glioma-genesis and a novel LEO1-SLC12A1 fusion gene. Genes Chromosomes Cancer 49: 509-517.
11. Zender L, Spector MS, Xue W, Flemming P, Cordon-Cardo C, et al. (2006) Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell 125: 1253-1267.
12. Yang ZQ, Streicher KL, Ray ME, Abrams J, Ethier SP (2006) Multiple interacting oncogenes on the 8p11-p12 amplicon in human breast cancer. Cancer Res 66: 11632-11643.
13. Kuuselo R, Savinainen K, Azorsa DO, Basu GD, Karhu R, et al. (2007) Intersex-like (IXL) is a cell survival regulator in pancreatic cancer with 19q13 amplification. Cancer Res 67: 1943-1949.
14. Vogt N, Lefevre SH, Apiou F, Dutrillaux AM, Cor A, et al. (2004) Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas. Proc Natl Acad Sci U S A 101: 11368-11373.
15. Gibaud A, Vogt N, Hadj-Hamou NS, Meyniel JP, Hupe P, et al. (2010) Extrachromosomal amplification mechanisms in a glioma with amplified sequences from multiple chromosome loci. Hum Mol Genet 19: 1276-1285.
16. Gan HK, Kaye AH, Luwor RB (2009) The EGFRvIII variant in glioblastoma multiforme. J Clin Neurosci 16: 748-754.
17. Nicholas MK, Lukas RV, Jafri NF, Faoro L, Salgia R (2006) Epidermal growth factor receptor - mediated signal transduction in the development and therapy of gliomas. Clin Cancer Res 12: 7261-7270.
18. Denoeud F, Kapranov P, Ucla C, Frankish A, Castelo R, et al. (2007) Prominent use of distal 59 transcription start sites and discovery of a large number of additional exons in ENCODE regions. Genome Res 17: 746-759.
19. Haley JD, Hsuan JJ, Waterfield MD (1989) Analysis of mammalian fibroblast transformation by normal and mutated human EGF receptors. Oncogene 4: 273-283.
20. Wong AJ, Ruppert JM, Bigner SH, Grzeschik CH, Humphrey PA, et al. (1992) Structural alterations of the epidermal growth factor receptor gene in human gliomas. Proc Natl Acad Sci U S A 89: 2965-2969.
21. Wu YL, Dudognon C, Nguyen E, Hillion J, Pendino F, et al. (2006) Immunodetection of human telomerase reverse-transcriptase (hTERT) reappraised: nucleolin and telomerase cross paths. J Cell Sci 119: 2797-2806.
22. Rao SK, Edwards J, Joshi AD, Siu IM, Riggins GJ (2009) A survey of glioblastoma genomic amplifications and deletions. J Neurooncol 96: 169-179.
23. Ruano Y, Mollejo M, Ribalta T, Fiano C, Camacho FI, et al. (2006) Identification of novel candidate target genes in amplicons of Glioblastoma multiforme tumors detected by expression and CGH microarray profiling. Mol Cancer 5: 39.
24. Kotliarov Y, Steed ME, Christopher N, Walling J, Su Q, et al. (2006) Highresolution global genomic survey of 178 gliomas reveals novel regions of copy number alteration and allelic imbalances. Cancer Res 66: 9428-9436.
25. Lu Z, Zhou L, Killela P, Rasheed AB, Di C, et al. (2009) Glioblastoma protooncogene SEC61gamma is required for tumor cell survival and response to endoplasmic reticulum stress. Cancer Res 69: 9105-9111.
26. Tchirkov A, Rolhion C, Kemeny JL, Irthum B, Puget S, et al. (2003) Clinical implications of quantitative real-time RT-PCR analysis of hTERT gene expression in human gliomas. Br J Cancer 88: 516-520.
27. Boldrini L, Pistolesi S, Gisfredi S, Ursino S, Ali G, et al. (2006) Telomerase activity and hTERT mRNA expression in glial tumors. Int J Oncol 28: 1555-1560.
28. Nowak T, Januszkiewicz D, Zawada M, Pernak M, Lewandowski K, et al. (2006) Amplification of hTERT and hTERC genes in leukemic cells with high expression and activity of telomerase. Oncol Rep 16: 301-305.
29. Greider CW (2006) Telomerase RNA levels limit the telomere length equilibrium. Cold Spring Harb Symp Quant Biol 71: 225-229.
30. Zhao P, Wang C, Fu Z, You Y, Cheng Y, et al. (2007) Lentiviral vector mediated siRNA knock-down of hTERT results in diminished capacity in invasiveness and in vivo growth of human glioma cells in a telomere lengthindependent manner. Int J Oncol 31: 361-368.
31. Muleris M, Almeida A, Dutrillaux AM, Pruchon E, Vega F, et al. (1994) Oncogene amplification in human gliomas: a molecular cytogenetic analysis. Oncogene 9: 2717-2722.
32. Kent WJ, Sugnet CW, Furey TS, Roskin KM, Pringle TH, et al. (2002) The human genome browser at UCSC. Genome Res 12: 996-1006.
33. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, et al. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034.
34. Gonin-Laurent N, Hadj-Hamou NS, Vogt N, Houdayer C, Gauthiers-Villars M, et al. (2007) RB1 and TP53 pathways in radiation-induced sarcomas. Oncogene 26: 6106-6112.
35. Wege H, Chui MS, Le HT, Tran JM, Zern MA (2003) SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity. Nucleic Acids Res 31: E3-3.
36. Pelosi G, Del Curto B, Trubia M, Nicholson AG, Manzotti M, et al. (2007) 3q26 Amplification and polysomy of chromosome 3 in squamous cell lesions of the lung: a fluorescence in situ hybridization study. Clin Cancer Res 13: 1995-2004.
37. Zhdanova NS, Minina JM, Karamisheva TV, Draskovic I, Rubtsov NB, et al. (2007) The very long telomeres in Sorex granarius (Soricidae, Eulipothyphla) contain ribosomal DNA. Chromosome Res 15: 881-890.