Synthesis of a single-molecule l-rhamnose-containing three-component vaccine and evaluation of antigenicity in the presence of anti-l-rhamnose antibodies

Journal of the American Chemical Society

Volumn 132, Issue 48, 2010, Pages 17236-17246

  Sarkar, Sourav ^a   Lombardo, Steven A ^b   Herner, Danielle N ^b   Talan, Rommel S ^a   Wall, Katherine A ^b   Sucheck, Steven J ^a  

^a UNIVERSITY OF TOLEDO   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY TITERS; ANTIGENICITY; BALB/C MICE; CONTROL GROUPS; IMMUNOGENICITY; IN-VITRO; L-RHAMNOSE; NEISSERIA MENINGITIDES; NEW APPROACHES; OPTIMAL CONDITIONS; OUTER MEMBRANE PROTEIN; OVALBUMINS; SINGLE-MOLECULE; SOLID PHASE PEPTIDE SYNTHESIS; T CELLS; T-CELL EPITOPES; THREE-COMPONENT; UPTAKE MECHANISM;

AMINO ACIDS; ANTIGENS; BIOLOGICAL MEMBRANES; CARBOHYDRATES; CELL PROLIFERATION; CHEMICAL MODIFICATION; IMMUNIZATION; SYNTHESIS (CHEMICAL); VACCINES;

ANTIBODIES;

ADJUVANT; ANTIBODY; ANTIGEN; EPITOPE; GLYCOPEPTIDE; N ACETYLGALACTOSAMINE; OUTER MEMBRANE PROTEIN; OVALBUMIN; RHAMNOSE; RHAMNOSE ANTIBODY; RHAMNOSE ANTIBODY OVALBUMIN CONJUGATE; THREONINE; TUMOR ANTIGEN; UNCLASSIFIED DRUG; VACCINE;

ANIMAL EXPERIMENT; ANTIBODY TITER; ANTIGEN PRESENTING CELL; ANTIGENICITY; ARTICLE; CONJUGATION; CONTROLLED STUDY; DEACETYLATION; DENDRITIC CELL; DILUTION; DRUG SYNTHESIS; EMULSION; FEMALE; HELPER CELL; IMMUNIZATION; IMMUNOGENICITY; LYMPHOCYTE PROLIFERATION; MOUSE; NEISSERIA MENINGITIDIS; NONHUMAN; SOLID PHASE SYNTHESIS; SPLEEN;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CELL PROLIFERATION; CHEMISTRY TECHNIQUES, SYNTHETIC; EPITOPES; FEMALE; HEMOCYANIN; MICE; MOLECULAR SEQUENCE DATA; RHAMNOSE; SERUM ALBUMIN, BOVINE; T-LYMPHOCYTES; TOLL-LIKE RECEPTORS; VACCINES;

EID: 78650077256     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja107029z     Document Type: Article

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