A novel and efficient method for synthetic carbohydrate conjugate vaccine preparation: Synthesis of sialyl Tn-KLH conjugate using a 4-(4-N-maleimidomethyl) cyclohexane-1-carboxyl hydrazide (MMCCH) linker arm

Glycoconjugate Journal

Volumn 15, Issue 3, 1998, Pages 217-221

  Ragupathi, Govindaswami ^a   Koganty, R Rao ^b   Qiu, Dongxu ^b   Lloyd, Kenneth O ^c   Livingston, Philip O ^a  

^a Memorial Hospital   (United States)

^b Biomira Inc   (Canada)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Cancer; Carbohydrate; Conjugation; Immunogen; Vaccines

Indexed keywords

4 (4 N MALEIMIDOMETHYL)CYCLOHEXANE 1 CARBOXYLHYDRAZIDE; ALDEHYDE DERIVATIVE; ANTIGEN; CANCER VACCINE; CARBOHYDRATE; EPITOPE; GLYCOPEPTIDE; KEYHOLE LIMPET HEMOCYANIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; CANCER IMMUNOTHERAPY; CONJUGATE; CONJUGATION; CONTROLLED STUDY; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; TECHNIQUE;

ANIMALS; ANTIBODY FORMATION; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CANCER VACCINES; CARBOHYDRATE SEQUENCE; CROSS-LINKING REAGENTS; EPITOPES; FEMALE; GLYCOCONJUGATES; HEMOCYANIN; HUMANS; IMMUNIZATION; MALEIMIDES; METHODS; MICE; MOLECULAR SEQUENCE DATA; VACCINES, CONJUGATE;

EID: 0031887869     PISSN: 02820080     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006936826730     Document Type: Article

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