Structure of human Stabilin-1 Interacting Chitinase-Like Protein (SI-CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivity

Journal of Biological Chemistry

Volumn 285, Issue 51, 2010, Pages 39898-39904

  Meng, Geng ^a   Zhao, Yanmei ^a,c   Bai, Xiaoyun ^a   Liu, Yong ^a   Green, Todd J ^b   Luo, Ming ^b   Zheng, Xiaofeng ^a  

^a PEKING UNIVERSITY   (China)

^b University of Alabama at Birmingham   (United States)

^c INSTITUTE OF BIOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADVERSE EFFECT; BINDING CAPACITIES; BINDING CLEFTS; BINDING PROPERTIES; BINDING SELECTIVITY; BIOCHEMICAL ANALYSIS; BIOLOGICAL FUNCTIONS; CHITINASES; CYTOKINES; DOMAIN-CONTAINING PROTEINS; ENDOTOXIN NEUTRALIZATION; GAIN INSIGHT; HOST DEFENSE; IN-VITRO; INFLAMMATORY REACTION; ISOMERASES; LIGAND BINDING; SECRETED PROTEIN;

BINDING ENERGY; MACROPHAGES; PROTEINS; SUGAR (SUCROSE); X RAY CRYSTALLOGRAPHY;

CRYSTAL STRUCTURE;

BINDING PROTEIN; CARBOHYDRATE; LIPOPOLYSACCHARIDE; OLIGOSACCHARIDE; STABILIN 1 INTERACTING CHITINASE LIKE PROTEIN; TRIOSEPHOSPHATE ISOMERASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOHYDRATE ANALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROPHAGE; PRIORITY JOURNAL; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN FUNCTION; PROTEIN STRUCTURE;

BINDING SITES; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIPOPOLYSACCHARIDES; OLIGOSACCHARIDES; PROTEIN BINDING; PROTEIN FOLDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78650069905     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.130781     Document Type: Article

References (22)

1. Zhu, Z., Zheng, T., Homer, R. J., Kim, Y. K., Chen, N. Y., Cohn, L., Hamid, Q., and Elias, J. A. (2004) Science 304, 1678-1682
2. Fusetti, F., von Moeller, H., Houston, D., Rozeboom, H. J., Dijkstra, B. W., Boot, R. G., Aerts, J. M., and van Aalten, D. M. (2002) J. Biol. Chem. 277, 25537-25544
3. Fusetti, F., Pijning, T., Kalk, K. H., Bos, E., and Dijkstra, B. W. (2003) J. Biol. Chem. 278, 37753-37760
4. Houston, D. R., Recklies, A. D., Krupa, J. C., and van Aalten, D. M. (2003) J. Biol. Chem. 278, 30206-30212
5. Sun, Y. J., Chang, N. C., Hung, S. I., Chang, A. C., Chou, C. C., and Hsiao, C. D. (2001) J. Biol. Chem. 276, 17507-17514
6. Chang, N. C., Hung, S. I., Hwa, K. Y., Kato, I., Chen, J. E., Liu, C. H., and Chang, A. C. (2001) J. Biol. Chem. 276, 17497-17506
7. Kzhyshkowska, J., Gratchev, A., and Goerdt, S. (2007) Biomark. Insights 2, 128-146
8. Kzhyshkowska, J., Mamidi, S., Gratchev, A., Kremmer, E., Schmuttermaier, C., Krusell, L., Haus, G., Utikal, J., Schledzewski, K., Scholtze, J., and Goerdt, S. (2006) Blood 107, 3221-3228
9. Dai, X., Chen, Q., Lian, M., Zhou, Y., Zhou, M., Lu, S., Chen, Y., Luo, J., Gu, X., Jiang, Y., Luo, M., and Zheng, X. (2005) Biochem. Biophys. Res. Commun. 332, 593-601
10. Meng, G., Bai, X., Green, T. J., Luo, M., and Zheng, X. (2009) Protein Pept. Lett. 16, 336-338
11. Powell, H. R. (1999) Acta Crystallogr. D Biol. Crystallogr. 55, 1690-1695
12. Collaborative Computational Project Number 4 (1994) Acta Crystallogr. D Biol. Crystallogr. 50, 760-763
13. Adams, P. D., Grosse-Kunstleve, R. W., Hung, L. W., Ioerger, T. R., Mc- Coy, A. J., Moriarty, N. W., Read, R. J., Sacchettini, J. C., Sauter, N. K., and Terwilliger, T. C. (2002) Acta Crystallogr. D Biol. Crystallogr. 58, 1948-1954
14. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. D Biol. Crystallogr. 54, 905-921
15. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2126-2132
16. Laskowski, R. A., Rullmannn, J. A., MacArthur, M. W., Kaptein, R., and Thornton, J. M. (1996) J. Biomol. NMR 8, 477-486
17. Rao, F. V., Houston, D. R., Boot, R. G., Aerts, J. M., Sakuda, S., and van Aalten, D. M. (2003) J. Biol. Chem. 278, 20110-20116
18. Beutler, B., and Rietschel, E. T. (2003) Nat. Rev. Immunol. 3, 169-176
19. Cohen, J. (2002) Nature 420, 885-891
20. Raetz, C. R. (1990) Annu. Rev. Biochem. 59, 129-170
21. Welch, J. S., Escoubet-Lozach, L., Sykes, D. B., Liddiard, K., Greaves, D. R., and Glass, C. K. (2002) J. Biol. Chem. 277, 42821-42829
22. Steenbakkers, P. G., Baeten, D., Rovers, E., Veys, E. M., Rijnders, A. W., Meijerink, J., De Keyser, F., and Boots, A. M. (2003) J. Immunol. 170, 5719-5727