Poloxamer 407 increases the recovery of paracetamol in the isolated perfused rat liver

Journal of Pharmaceutical Sciences

Volumn 100, Issue 1, 2011, Pages 334-340

  Mitchell, Sarah J ^a,b   Huizer Pajkos, Aniko ^a   Cogger, Victoria C ^b,c,d   McLachlan, Andrew J ^c,d   Le Couteur, David G ^b,c,d   Hilmer, Sarah N ^a,b  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c ANZAC Research Institute   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Disposition; Elimination; Endothelial; Hepatic clearance; Hepatic metabolism; Hepatocytes; Pharmacokinetics pharmacodynamics; Protein binding; Surfactants

Indexed keywords

CARBON 14; PARACETAMOL; POLOXAMER; SUCROSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG DISPOSITION; DRUG DISTRIBUTION; ENDOTHELIUM CELL; FENESTRATION; LIPID BLOOD LEVEL; LIVER SINUSOID; LIVER SINUSOIDAL ENDOTHELIAL CELL; MALE; MEMBRANE PERMEABILITY; NONHUMAN; RAT; SCANNING ELECTRON MICROSCOPY;

EID: 78650069556     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22235     Document Type: Article

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