Disruption of plasminogen activator inhibitor-1 gene enhances spontaneous enlargement of mouse airspace with increasing age

Tohoku Journal of Experimental Medicine

Volumn 222, Issue 4, 2010, Pages 291-296

  Hu, Hua ^a   Zhao, Yanyan ^b   Xiao, Yao ^a   Zhang, Ruxin ^a   Song, Houyan ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Age; Elastin; Matrix metalloproteinase 12; Plasminogen activator inhibitor 1; Transforming growth factor 1

Indexed keywords

ELASTIN; MACROPHAGE ELASTASE; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRANSFORMING GROWTH FACTOR BETA1;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE DISRUPTION; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LUNG EMPHYSEMA; LUNG STRUCTURE; MALE; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WILD TYPE;

AGING; ANIMALS; ELASTIN; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYPERTROPHY; LUNG; MALE; MATRIX METALLOPROTEINASE 12; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; PLASMINOGEN ACTIVATOR INHIBITOR 1; PULMONARY ALVEOLI; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 78650061671     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.222.291     Document Type: Article

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