Oral administration of L-mR18L, a single domain cationic amphipathic helical peptide, inhibits lesion formation in ApoE null mice

Journal of Lipid Research

Volumn 51, Issue 12, 2010, Pages 3491-3499

  Handattu, Shaila P ^a   Datta, Geeta ^a   Epand, Richard M ^c   Epand, Raquel F ^c   Palgunachari, Mayakonda N ^a   Mishra, Vinod K ^a   Monroe, Candyce E ^a   Keenum, Tamara D ^a   Chaddha, Manjula ^a   Anantharamaiah, G M ^a,b   Garber, David W ^a  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

Animals; Atherosclerosis; Cholesterol; Lipids; Metabolism

Indexed keywords

ACETYLGLYCYLPHENYLALANYLARGINYLARGINYLPHENYLALANYLLEUCYLGLYCYLSERYLTRYPTOPHANYLALANYLARGINYLISOLEUCYLTYROSYLARGINYLALANYLPHENYLALANYLVALYLGLYCINEAMIDE; ACETYLGLYCYLPHENYLALANYLLYSYLLYSYLPHENYLALANYLLEUCYLGLYCYLSERYLTRYPTOPHANYLALANYLLYSYLISOLEUCYLTYROSYLLYSYLALANYLPHENYLALANYLVALYLGLYCINEAMIDE; APOLIPOPROTEIN E; ARGININE; CHOLESTEROL; LOW DENSITY LIPOPROTEIN; LYSINE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AORTA SINUS; ARTICLE; ATHEROSCLEROSIS; CELL ADHESION; CELL STRAIN HEPG2; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFICACY; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; AORTIC ANEURYSM; ARGININE; ATHEROSCLEROSIS; CATIONS; CELL ADHESION; CHOLESTEROL; ENDOTHELIAL CELLS; HEP G2 CELLS; HUMANS; LIPID METABOLISM; LYSINE; MICE; MICE, KNOCKOUT; MONOCYTES; MYELIN BASIC PROTEINS; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 78650059591     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M006916     Document Type: Article

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