Anti-inflammatory and recycling properties of an apolipoprotein mimetic peptide, Ac-hE18A-NH2

Atherosclerosis

Volumn 208, Issue 1, 2010, Pages 134-141

  Datta, Geeta ^a   White, C Roger ^b   Dashti, Nassrin ^a   Chaddha, Manjula ^a   Palgunachari, Mayakonda N ^a   Gupta, Himanshu ^b   Handattu, Shaila P ^a   Garber, David W ^a   Anantharamaiah, G M ^a,c  

^a UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

apoA I; apoE mimetic; HepG2; Macrophages; MCP 1; pre HDL; Recycling; VCAM 1

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN E; CHOLESTEROL; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PEPTIDOMIMETIC AGENT; PRE BETA HIGH DENSITY LIPOPROTEIN; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CELL ADHESION; CELL CULTURE; CELL STRAIN HEPG2; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATORY DISEASE; LIPOPROTEIN SECRETION; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UMBILICAL VEIN;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; HIGH-DENSITY LIPOPROTEINS, PRE-BETA; HUMANS; INFLAMMATION; LIPOPROTEINS; PEPTIDE FRAGMENTS; PEPTIDES; RABBITS; TIME FACTORS;

EID: 73449093793     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.07.019     Document Type: Article

References (44)

1. Hui D.Y. Apolipoprotein E-induced cell signaling in the vessel wall. Rev Endocr Metab Disorders 5 (2004) 335-341
2. Swertfeger D.K., and Hui D.Y. Apolipoprotein E: A cholesterol transport protein with lipid transport independent cell signaling properties. Front BioSci 6 (2001) P526-535
3. Shimano H.N., Yamada N., Katsuki N., et al. Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apo E. J Clin Invest 90 (1992) 2084-2091
4. Zang S.H., Reddick R.L., Piedrahita J.A., Hagaman J.R., Oliver P.M., and Maeda N. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 258 (1992) 468-471
5. Mahley R.W., Weisgraber K.H., Hussein M.M., et al. Intravenous infusion of apolipoprotein E accelerates clearance of plasma lipoprotein in rabbits. J Clin Invest 83 (1989) 2125-2130
6. Hasse A.H., Linton M.R., Sanon D., Swift L.L., and Fazio S. Determination of lower threshold of apolipoproteinE resulting in lipoprotein remnant clearance. J Lipid Res 40 (1999) 1529-1538
7. Burgess J.W., Liang P., Vaidyanath C., and Marcel Y.L. ApoE of the HepG2 cell surface includes a major pool associated with chondroitin sulfate proteoglycans. Biochemistry 38 (1999) 524-531
8. Swift L.L., Farkas M.H., Major A.S., Valyi-Nagy K., Linton M.F., and Fazio S. A recycling pathway for resecretion of internalized apolipoprotein E in liver cells. J Biol Chem 276 (2001) 22965-22970
9. Farkas M.H., Swift L.L., Hasty A.H., Linton M.F., and Fazio S. The recycling of apolipoprotein E in primary cultures of mouse hepatocytes. J Biol Chem 278 (2003) 9412-9417
10. Heeren J., Grewal T., Jackie S., and Beisiegel U.J. Recycling of apolipoprotein E and lipoprotein lipase through endosomal compartments in vivo. J Biol Chem 276 (2001) 42333-42338
11. Glomset J.A. The plasma lecithin:cholesterol acyl transferase reaction. J Lipid Res 9 (1968) 155-167
12. Kontush A., and Chapman M.J. Antiatherogenic small, dense HDL-guardian angel of the arterial wall?. Nat Clin Pract 3 (2006) 144-153
13. Kennedy M.A., Barrera G.C., Nakamura K., et al. ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation. Cell Metab 1 (2005) 121-131
14. Kontush A., Chantepie S., and Chapman M.J. Small, dense HDL particles exert potent protection of atherogenic LDL against oxidative stress. Arterioscler Thromb Vasc Biol 23 (2003) 1881-1888
15. Barter P.J., Nicholls S., Rye K.-A., Anantharamiah G.M., Navab M., and Fogelman A.M. Antiinflammatory properties of HDL. Circ Res 95 (2004) 764-772
16. Baker P.W., Rye K.A., Gamble J.R., Vadas M.A., and Barter P.J. Ability of reconstituted high density lipoproteins to inhibit cytokine-induced expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells. J Lipid Res 40 (1999) 345-353
17. Heeren J., Grewal T., Laatsch A., et al. Recycling of Apoprotein E Is associated with cholesterol efflux and high density lipoprotein internalization. J Biol Chem 278 (2003) 14370-14378
18. Wilson C., Wardell M.R., Weisgraber K.H., Mahley R.W., and Agard D.A. Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E. Science 252 (1991) 1817-1822
19. Anantharamaiah G.M., Mishra V.K., Garber D.W., et al. Structural requirements for antioxidative and anti-inflammatory properties of apolipoprotein A-I mimetic peptides. J Lipid Res 48 (2007) 1915-1923
20. Anantharamaiah G.M., Jones J.L., Brouillette C.G., et al. Studies of synthetic peptide analogs of the amphipathic helix. Structure of complexes with dimyristoyl phosphatidylcholine. J Biol Chem 260 (1985) 10248-10255
21. Datta G., Chaddha M., Garber D.W., et al. The receptor binding domain of apolipoprotein E, linked to a model class A amphipathic helix, enhances internalization and degradation of LDL by fibroblasts. Biochemistry 39 (2000) 213-220
22. Gupta H., White C.R., Handattu S., et al. Apolipoprotein E mimetic peptide dramatically lowers plasma cholesterol and restores endothelial function in Watanabe Heritable Hyperlipidemic rabbits. Circulation 111 (2005) 3112-3118
23. Garber D.W., Handattu S., Aslan I., Datta G., Chaddha M., and Anantharamaiah G.M. Effect of an arginine-rich helical peptide on plasma cholesterol in dyslipidemic mice. Atherosclerosis 168 (2003) 229-237
24. Curry M.D., McConathy W.J., Alaupovic P., Ledford J.H., and Popovic M. Determination of human apolipoprotein E by electroimmuniassay. Biochem Biophys Acta 439 (1976) 413-425
25. Bilheimer D.W., Eisenberg S., and Levy R.I. The metabolism of very low density lipoproteins. I. Preliminary in vitro and in vivo observations. Biochim Biophys Acta 260 (1972) 212-221
26. Manchekar M., Richardson P.E., Forte T., Datta G., Segrest J.P., and Dashti N. Apolipoprotein B-containing lipoprotein particle assembly. J Biol Chem 279 (2004) 39757-39766
27. Manchekar M., Richardson P.E., Sun Z., Liu Y., Segrest J.P., and Dashti N. Charged amino acid residues 997-1000 of human apolipoprotein B100 Are critical for the initiation of lipoprotein assembly and the formation of a stable lipidated primordial particle in McA-RH7777 cells. J Biol Chem 283 (2008) 29251-29265
28. Kritharides L., Christian A., Stoudt G., Morel D., and Rothblat G.H. Choelsterol metabolism and efflux in human THP-1 macrophages. Arterioscler Thromb Vasc Biol 18 (1998) 1589-1599
29. Gupta H., Dai L., Datta G., et al. Inhibition of lipopolysaccharide-induced inflammatory responses by an apolipoprotein AI mimetic peptide. Circ Res 97 (2005) 236-243
30. Chung B.H., Anantharamaiah G.M., Brouillette C.G., Nishida T., and Segrest J.P. Studies of synthetic peptide analogs of the amphipathic helix. Correlation of structure with function. J Biol Chem 260 (1985) 10256-10262
31. Kockx M., Rye K.-A., Gaus K., et al. Apolipoprotein A-I-stimulated apolipoprotein E secretion from human macrophages is independent of cholesterol efflux. J Biol Chem 279 (2004) 25966-25977
32. Lilly-Stauderman M., Brown T.L., Balasubramaniam A., and Harmony J.A.K. Heparin releases newly synthesized cell surface-associated apolipoprotein E from HepG2 cells. J Lipid Res 34 (1993) 190-200
33. Navab M., Anantharamaiah G.M., Reddy S.T., et al. Apolipoprotein A-I mimetic peptides. Arterioscler Thromb Vasc Biol 25 (2005) 1335-1341
34. Remaley A.T., Thomas F., Stonik J.A., et al. Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway. J Lipid Res 44 (2003) 828-836
35. Navab M., Anantharamaiah G.M., Reddy S.T., et al. Oral D-4F causes formation of pre-ß high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice. Circulation 109 (2004) 3215-3220
36. Hasty A.H., Plummer M.R., Weisgraber K.H., Linton M.F., Fazio S., and Swift L.L. The recycling of apolipoprotein E in macrophages: influence of HDL and apolipoprotein A-I. J Lipid Res 46 (2005) 1433-1439
37. Yancey P.G., Bortnick A.E., Kellner-Weibel G., Llera-Moya M., Phillips M.C., and Rothblat G.H. Importance of different pathways of cellular cholesterol efflux. Arterioscler Thromb Vasc Biol 23 (2003) 712-719
38. Braun N.A., Mohler P.J., Weisgraber K.H., et al. Intracelluar trafficking of recycling apolipoprotein E in Chinese hamster ovary cells. J Lipid Res 47 (2006) 1176-1186
39. Hasty A.H., Linton M.F., Brandt S.J., Babaev V.R., Gleaves L.A., and Fazio S. Retroviral gene therapy in apoE-deficient mice: apoE expression in the artery wall reduces early foam cell lesion formation. Circulation 99 (1999) 2571-2576
40. Stannard A.K., Riddell D.R., Sacre S.M., et al. Cell-derived apolipoprotein E (ApoE) particles inhibit vascular cell adhesion molecule-1 (VCAM-1) expression in human endothelial cells. J Biol Chem 276 (2001) 46011-46016
41. Zhu Y., and Hui D.Y. Apolipoprotein E binding to low density lipoprotein receptor-related protein-1 inhibits cell migration via activation of cAMP-dependent protein kinase A. J Biol Chem 278 (2003) 36257-36263
42. Lin C.Y., Duan H.W., and Mazzone T. Apolipoprotein E-dependent cholesterol efflux from macrophages: kinetic study and divergent mechanisms for endogenous versus exogenous apolipoprotein E. J Lipid Res 40 (1999) 1618-1626
43. Huang Z.H., Fitzgerald M.L., and Mazzone T. Distinct cellular loci for the ABCA1-dependent and ABCA1-independent lipid efflux mediated by endogenous apolipoprotein E expression. Arterioscler Thromb Vasc Biol 26 (2006) 157-162
44. Kawamura A., Baitsch D., Telgmann R., et al. Apolipoprotein E interrupts interleukin-1β signaling in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 27 (2007) 1610-1617