Inducible nerve growth factor delivery for peripheral nerve regeneration in vivo

Plastic and Reconstructive Surgery

Volumn 126, Issue 6, 2010, Pages 1874-1889

  Scholz, Thomas ^a   Rogers, Jason M ^a   Krichevsky, Alisa ^a   Dhar, Sanjay ^a   Evans, Gregory R D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; DRUG DERIVATIVE; ECDYSTERONE; GANCICLOVIR; NERVE GROWTH FACTOR; PONASTERONE A;

ANIMAL; ARTICLE; CELL STRAIN HEK293; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFECT; HUMAN; METHODOLOGY; NERVE CONDUCTION; NERVE FIBER; NERVE REGENERATION; NUDE RAT; PERIPHERAL NERVE; RAT; SCIATIC NERVE; SECRETION; TISSUE ENGINEERING;

ANIMALS; ANTIVIRAL AGENTS; AXONS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; ECDYSTERONE; GANCICLOVIR; HEK293 CELLS; HUMANS; NERVE GROWTH FACTOR; NERVE REGENERATION; NEURAL CONDUCTION; PERIPHERAL NERVES; RATS; RATS, NUDE; SCIATIC NERVE; TISSUE ENGINEERING;

EID: 78650057592     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/PRS.0b013e3181f5274e     Document Type: Article

References (68)

1. Noble J, Munro CA, Prasad VS, Midha R. Analysis of upper and lower extremity peripheral nerve injuries in a population of patients with multiple injuries. J Trauma 1998;45:116-122.
2. Dahlin LB, Lundborg G. Use of tubes in peripheral nerve repair. Neurosurg Clin N Am. 2001;12:341-352.
3. Doolabh VB, Hertl MC, Mackinnon SE. The role of conduits in nerve repair: A review. Rev Neurosci. 1996;7:47-84.
4. Millesi H. Nerve grafting. Clin Plast Surg. 1984;11:105-113.
5. Mackinnon SE, Hudson AR. Clinical application of peripheral nerve transplantation. Plast Reconstr Surg. 1992;90:695-699.
6. Ortiguela ME, Wood MB, Cahill DR. Anatomy of the sural nerve complex. J Hand Surg (Am.) 1987;12:1119-1123.
7. Kim DH, Cho YJ, Tiel RL, Kline DG. Outcomes of surgery in 1019 brachial plexus lesions treated at Louisiana State University Health Sciences Center. J Neurosurg. 2003;98:1005-1016.
8. Jaquet JB, Luijsterburg AJ, Kalmijn S, Kuypers PD, Hofman A, Hovius SE. Median, ulnar, and combined median-ulnar nerve injuries: Functional outcome and return to productivity. J Trauma 2001;51:687-692.
9. de Medinaceli L, Prayon M, Merle M. Percentage of nerve injuries in which primary repair can be achieved by end-toend approximation: Review of 2,181 nerve lesions. Microsurgery 1993;14:244-246.
10. Beazley WC, Milek MA, Reiss BH. Results of nerve grafting in severe soft tissue injuries. Clin Orthop Relat Res. 1984;188:208-212.
11. Kline DG, Kim D, Midha R, Harsh C, Tiel R. Management and results of sciatic nerve injuries: A 24-year experience. J Neurosurg. 1998;89:13-23.
12. Midha R. Nerve transfers for severe brachial plexus injuries: A review. Neurosurg Focus 2004;16:E5.
13. Millesi H. Reappraisal of nerve repair. Surg Clin North Am. 1981;61:321-340.
14. Dellon AL, Mackinnon SE. An alternative to the classical nerve graft for the management of the short nerve gap. Plast Reconstr Surg. 1988;82:849-856.
15. Pfister LA, Papaloizos M, Merkle HP, Gander B. Nerve conduits and growth factor delivery in peripheral nerve repair. J Peripher Nerv Syst. 2007;12:65-82.
16. Hudson TW, Evans GR, Schmidt CE. Engineering strategies for peripheral nerve repair. Clin Plast Surg. 1999;26:617-628.
17. Ebadi M, Bashir RM, Heidrick ML, et al. Neurotrophins and their receptors in nerve injury and repair. Neurochem Int. 1997;30:347-374.
18. Fu SY, Gordon T. The cellular and molecular basis of peripheral nerve regeneration. Mol Neurobiol. 1997;14:67-116.
19. Lykissas MG, Batistatou AK, Charalabopoulos KA, Beris AE. The role of neurotrophins in axonal growth, guidance, and regeneration. Curr Neurovasc Res. 2007;4:143-151.
20. Raivich G, Kreutzberg GW. Peripheral nerve regeneration: Role of growth factors and their receptors. Int J Dev Neurosci. 1993;11:311-324. (Pubitemid 23213573)
21. McConnell MP, Dhar S, Nguyen T, et al. Nerve growth factor expression response to induction agent booster dosing in transfected human embryonic kidney cells. Plast Reconstr Surg. 2005;115:506-514.
22. McConnell MP, Dhar S, Naran S, Nguyen T, Bradshaw RA, Evans GR. In vivo induction and delivery of nerve growth factor, using HEK-293 cells. Tissue Eng. 2004;10:1492-1501.
23. Dhar S, McConnell MP, Gharibjanian NA, et al. Herpes simplex virus-thymidine kinase-based suicide gene therapy as a "molecular switch off" for nerve growth factor production in vitro. Tissue Eng. 2007;13:2357-2365.
24. Jimenez JC, Tyson DR, Dhar S, et al. Human embryonic kidney cells (HEK-293 cells): Characterization and dose-response relationship for modulated release of nerve growth factor for nerve regeneration. Plast Reconstr Surg. 2004;113:605-610.
25. Sterne GD, Brown RA, Green CJ, Terenghi G. Neurotrophin-3 delivered locally via fibronectin mats enhances peripheral nerve regeneration. Eur J Neurosci. 1997;9:1388-1396.
26. Varejao AS, Cabrita AM, Meek MF, et al. Functional and morphological assessment of a standardized rat sciatic nerve crush injury with a non-serrated clamp. J Neurotrauma 2004 21:1652-1670.
27. Bain JR, Mackinnon SE, Hunter DA. Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat. Plast Reconstr Surg. 1989;83:129-138.
28. Thalhammer JG, Vladimirova M, Bershadsky B, Strichartz GR. Neurologic evaluation of the rat during sciatic nerve block with lidocaine. Anesthesiology 1995;82:1013-1025.
29. Koka R, Hadlock TA. Quantification of functional recovery following rat sciatic nerve transection. Exp Neurol. 2001;168: 192-195.
30. Sobeski JK, Kerns JM, Safanda JF, Shott S, Gonzalez MH. Functional and structural effects of GM-1 ganglioside treatment on peripheral nerve grafting in the rat. Microsurgery 2001;21:108-115.
31. Kobayashi J, Mackinnon SE, Watanabe O, et al. The effect of duration of muscle denervation on functional recovery in the rat model. Muscle Nerve 1997;20:858-866.
32. Tischler AS, Greene LA. Phenotypic plasticity of pheochromocytoma and normal adrenal medullary cells. Adv Biochem Psychopharmacol. 1980;25:61-68.
33. Doupe AJ, Landis SC, Patterson PH. Environmental influences in the development of neural crest derivatives: Glucocorticoids, growth factors, and chromaffin cell plasticity. J Neurosci. 1985;5:2119-2142.
34. Varejao AS, Melo-Pinto P, Meek MF, Filipe VM, Bulas-Cruz J. Methods for the experimental functional assessment of rat sciatic nerve regeneration. Neurol Res. 2004;26:186-194.
35. Boyd JG, Gordon T. Neurotrophic factors and their receptors in axonal regeneration and functional recovery after peripheral nerve injury. Mol Neurobiol. 2003;27:277-324.
36. Kingham PJ, Terenghi G. Bioengineered nerve regeneration and muscle reinnervation. J Anat. 2006;209:511-526.
37. Chen MH, Chen PR, Hsieh ST, Lin FH. Gelatin-tricalcium phosphate membranes immobilized with NGF, BDNF, or IGF-1 for peripheral nerve repair: An in vitro and in vivo study. J Biomed Mater Res A 2006;79:846-857.
38. Xu X, Yee WC, Hwang PY, et al. Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits. Biomaterials 2003;24:2405-2412.
39. Derby A, Engleman VW, Frierdich GE, Neises G, Rapp SR, Roufa DG. Nerve growth factor facilitates regeneration across nerve gaps: Morphological and behavioral studies in rat sciatic nerve. Exp Neurol. 1993;119:176-191.
40. McCallister WV, McCallister EL, Dubois B, Trumble TE. Regeneration along intact nerves using nerve growth factor and ciliary neurotrophic factor. J Reconstr Microsurg. 2004;20:473-481.
41. Hollowell JP, Villadiego A, Rich KM. Sciatic nerve regeneration across gaps within silicone chambers: Long-term effects of NGF and consideration of axonal branching. Exp Neurol. 1990;110:45-51.
42. Yu X, Bellamkonda RV. Tissue-engineered scaffolds are effective alternatives to autografts for bridging peripheral nerve gaps. Tissue Eng. 2003;9:421-430.
43. Rich KM, Alexander TD, Pryor JC, Hollowell JP. Nerve growth factor enhances regeneration through silicone chambers. Exp Neurol. 1989;105:162-170.
44. Lee AC, Yu VM, Lowe JB III, et al. Controlled release of nerve growth factor enhances sciatic nerve regeneration. Exp Neurol. 2003;184:295-303.
45. Young C, Miller E, Nicklous DM, Hoffman JR. Nerve growth factor and neurotrophin-3 affect functional recovery following peripheral nerve injury differently. Restor Neurol Neurosci. 2001;18:167-175.
46. He C, Chen Z. Enhancement of motor nerve regeneration by nerve growth factor. Microsurgery 1992;13:151-154.
47. Whitworth IH, Brown RA, Dore CJ, Anand P, Green CJ, Terenghi G. Nerve growth factor enhances nerve regeneration through fibronectin grafts. J Hand Surg (Br.) 1996;21:514-522.
48. Fine EG, Decosterd I, Papaloizos M, Zurn AD, Aebischer P. GDNF and NGF released by synthetic guidance channels support sciatic nerve regeneration across a long gap. Eur J Neurosci. 2002;15:589-601.
49. Gravvanis AI, Tsoutsos DA, Tagaris GA, et al. Beneficial effect of nerve growth factor-7S on peripheral nerve regeneration through inside-out vein grafts: An experimental study. Microsurgery 2004;24:408-415.
50. Mohammad JA, Warnke PH, Pan YC, Shenaq S. Increased axonal regeneration through a biodegradable amnionic tube nerve conduit: Effect of local delivery and incorporation of nerve growth factor/hyaluronic acid media. Ann Plast Surg. 2000;44:59-64.
51. Kemp SW, Walsh SK, Zochodne DW, Midha R. A novel method for establishing daily in vivo concentration gradients of soluble nerve growth factor (NGF). J Neurosci Methods 2007;165:83-88.
52. Bloch J, Fine EG, Bouche N, Zurn AD, Aebischer P. Nerve growth factor- and neurotrophin-3-releasing guidance channels promote regeneration of the transected rat dorsal root. Exp Neurol. 2001;172:425-432.
53. Ahmed Z, Brown RA, Ljungberg C, Wiberg M, Terenghi G. Nerve growth factor enhances peripheral nerve regeneration in non-human primates. Scand J Plast Reconstr Surg Hand Surg. 1999;33:393-401.
54. Dodla MC, Bellamkonda RV. Differences between the effect of anisotropic and isotropic laminin and nerve growth factor presenting scaffolds on nerve regeneration across long peripheral nerve gaps. Biomaterials 2008;29:33-46.
55. Sun W, Lin H, Chen B, Zhao W, Zhao Y, Dai J. Promotion of peripheral nerve growth by collagen scaffolds loaded with collagen-targeting human nerve growth factor-beta. J Biomed Mater Res A 2007;83:1054-1061.
56. Terenghi G. Peripheral nerve regeneration and neurotrophic factors. J Anat. 1999;194:1-14.
57. Sendtner M, Holtmann B, Kolbeck R, Thoenen H, Barde YA. Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 1992; 360:757-759.
58. Miyata Y, Kashihara Y, Homma S, Kuno M. Effects of nerve growth factor on the survival and synaptic function of Ia sensory neurons axotomized in neonatal rats. J Neurosci. 1986;6:2012-2018.
59. Martins RS, Siqueira MG, da Silva CF, Plese JP. Correlation between parameters of electrophysiological, histomorphometric and sciatic functional index evaluations after rat sciatic nerve repair. Arq Neuropsiquiatr. 2006;64:750-756.
60. Wolthers M, Moldovan M, Binderup T, Schmalbruch H, Krarup C. Comparative electrophysiological, functional, and histological studies of nerve lesions in rats. Microsurgery 2005; 25:508-519.
61. Belkas JS, Shoichet MS, Midha R. Peripheral nerve regeneration through guidance tubes. Neurol Res. 2004;26:151-160. (Pubitemid 38419098)
62. Mackinnon SE, Dellon AL, O'Brien JP. Changes in nerve fiber numbers distal to a nerve repair in the rat sciatic nerve model. Muscle Nerve 1991;14:1116-1122.
63. Wong BJ, Mattox DE. Experimental nerve regeneration: A review. Otolaryngol Clin North Am. 1991;24:739-752.
64. Beris A, Lykissas M, Korompilias A, Mitsionis G. End-to-side nerve repair in peripheral nerve injury. J Neurotrauma 2007; 24:909-916.
65. Rath S, Green CJ. Selectivity of distal reinnervation of regenerating mixed motor and sensory nerve fibres across muscle grafts in rats. Br J Plast Surg. 1991;44:215-218.
66. Brushart TM. Preferential reinnervation of motor nerves by regenerating motor axons. J Neurosci. 1988;8:1026-1031.
67. Brushart TM. Motor axons preferentially reinnervate motor pathways. J Neurosci. 1993;13:2730-2738.
68. Terzis J, Smith K. Repair and grafting of the peripheral nerve. In: McCarthy J, ed. General Principles in Plastic Surgery. Philadelphia: Saunders; 1990.