Prevalence of hyperthyroidism after exposure during childhood or adolescence to radioiodines from the Chornobyl nuclear accident: Dose-response results from the Ukrainian-American cohort study

Radiation Research

Volumn 174, Issue 6 A, 2010, Pages 763-772

  Hatch, M ^a   Furukawa, K ^a,b   Brenner, A ^a   Olinjyk, V ^c   Ron, E ^a   Zablotska, L ^d   Terekhova, G ^c   McConnell, R ^e   Markov, V ^c   Shpak, V ^c   Ostroumova, E ^a,f   Bouville, A ^a   Tronko, M ^c  

^a NATIONAL CANCER INSTITUTE   (United States)

^b RADIATION EFFECTS RESEARCH FOUNDATION   (Japan)

^c V P Komisarenko Institute of Endocrinology and Metabolism of the Ukraine Academy of Medical Sciences   (Ukraine)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Columbia University ^*  (United States)

^f INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IODINE 131; THYROTROPIN;

ADOLESCENCE; ADOLESCENT; ADULT; ARTICLE; CHERNOBYL ACCIDENT; CHILD; CHILDHOOD; CLINICAL ASSESSMENT; COHORT ANALYSIS; DOSE RESPONSE; DOSIMETRY; FEMALE; HUMAN; HYPERTHYROIDISM; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; RADIOACTIVITY; RISK FACTOR; SCHOOL CHILD; THYROTROPIN BLOOD LEVEL; UKRAINE;

ADOLESCENT; ADULT; CHERNOBYL NUCLEAR ACCIDENT; CHILD; COHORT STUDIES; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; HYPERTHYROIDISM; IODINE RADIOISOTOPES; MALE; PREVALENCE; RISK FACTORS; THYROTROPIN; THYROXINE; TRIIODOTHYRONINE;

EID: 78650018349     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR2003.1     Document Type: Article

References (39)

1. M. Vanderpump, The epidemiology of thyroid diseases. In Werner & Ingbar's The Thyroid: A Fundamental and Clinical Text (L. Braverman and R. D. Utiger, Eds.), pp. 398-406. Lippincott Williams & Wilkins, Philadelphia, 2005.
2. E. Marqusee, S. T. Haden and R. D. Utiger, Subclinical thyrotoxicosis. Endocrinol. Metab. Clin. North Am. 27, 37-49 (1998).
3. W. M. Wiersinga, Subclinical hypothyroidism and hyperthyroidism. I. Prevalence and clinical relevance. Neth. J. Med. 46, 197-204 (1995).
4. B. Biondi, E.A. Palmieri, M. Klain, M. Schlumberger, S. Filetti and G. Lombardi, Subclinical hyperthyroidism: clinical features and treatment options. Eur. J. Endocrinol. 152, 1-9 (2005).
5. T. C. Evans, Thyroid disease. Prim. Care Clin. Office Pract. 30, 625-640 (2003).
6. C. R. Eheman, P. Garbe and R. M. Tuttle, Autoimmune thyroid disease associated with environmental thyroidal irradiation. Thyroid 13, 453-464 (2003).
7. M. D. Tronko, G. R. Howe, T. I. Bogdanova, A. C. Bouville, O. V. Epstein, A. B. Brill, I. A. Likhtarev, D. J. Fink, V. V. Markov and G. W. Beebe, A cohort study of thyroid cancer and other thyroid diseases after the Chornobyl accident: thyroid cancer in Ukraine detected during first screening. J. Natl. Cancer Inst. 98, 897-903 (2006).
8. 131I in childhood. J. Natl. Cancer Inst. 97, 724-732 (2005). (Pubitemid 40872379)
9. S. Davis, K. J. Kopecky, T. E. Hamilton and L. Onstad, Thyroid neoplasia, autoimmune thyroiditis, and hypothyroidism in persons exposed to iodine 131 from the Hanford nuclear site. J. Am. Med. Assoc. 292, 2600-2613 (2004).
10. F. Pacini, T. Vorontsova, E. Molinaro, E. Kuchinskaya, L. Agate, E. Shavrova, L. Astachova, L. Chiovato and A. Pinchera, Prevalence of thyroid autoantibodies in children and adolescents from Belarus exposed to the Chernobyl radioactive fallout. Lancet 352, 763-766 (1998).
11. L. Agate, S. Mariotti, R. Elisei, P. Mossa, F. Pacini, E. Molinaro, L. Grasso, L. Masserini, T. Mokhort and A. Pinchera, Thyroid autoantibodies and thyroid function in subjects exposed to Chernobyl fallout during childhood: Evidence for a transient radiation-induced elevation of serum thyroid antibodies without an increase in thyroid autoimmune disease. J. Clin. Endocrinol. Metab. 93, 2729-2736 (2008).
12. F. Vermiglio, M. G. Castagna, E. Volnova, V. P. Lo Presti, M. Moleti, M. A. Violi, A. Artemisia and F. Trimarchi, Post- Chernobyl increased prevalence of humoral thyroid autoimmunity in children and adolescents from a moderately iodine-deficient area in Russia. Thyroid 9, 781-786 (1999).
13. J. R. Goldsmith, C. M. Grossman, W. E. Morton, R. H. Nussbaum, E. A. Kordysh, M. R. Quastel, R. B. Sobel and F. D. Nussbaum, Juvenile hypothyroidism among two populations exposed to radioiodine. Environ. Health Perspect. 107, 303-308 (1999).
14. M. R. Quastel, J. R. Goldsmith, L. Mirkin, S. Poljak, Y. Barki, J. Levy and R. Gorodischer, Thyroid-stimulating hormone levels in children from Chernobyl. Environ. Health Perspect. 105 (Suppl. 6), 1497-1498 (1997).
15. 131I dosedependent thyroid autoimmune disorders in children living around Chernobyl. Clin. Immunol. Immunopathol. 84, 251-259 (1997).
16. E. P. Kasatkina, D. E. Shilin, A. L. Rosenbloom, M. I. Pykov, G. V. Ibragimova, V. N. Sokolovskaya, A. N. Matkovskaya, T. N. Volkova, E. A. Odoud and N. M. Mursankova, Effects of low level radiation from the Chernobyl accident in a population with iodine deficiency. Eur. J. Pediatr. 156, 916-920 (1997).
17. E. Ostroumova, A. Brenner, V. A. Oliynyk, R. McConnell, J. Robbins, G. M. Terekhova, L. Zablotska, I. Likhtarev, A. Bouville and M. Hatch, Prevalence of subclinical hypothyroidism following environmental radioiodine exposure: Results from the Ukrainian-American cohort study of thyroid cancer and other thyroid diseases after the Chornobyl accident (1998-2000). Environ. Health Perspect. 117, 745-750 (2009).
18. M. D. Tronko, A. V. Brenner, V. A. Olijnyk, J. Robbins, O. V. Epstein, R. J. McConnell, T. I. Bogdanova, D. J. Fink, I. A. Likhtarev and G. R. Howe, Autoimmune thyroiditis and exposure to iodine 131 in the Ukrainian cohort study of thyroid cancer and other thyroid diseases after the Chornobyl accident: Results from the first screening cycle (1998-2000). J. Clin. Endocrinol. Metab. 91, 4344-4351 (2006).
19. R. A. Kerber, J. E. Till, S. L. Simon, J. L. Lyon, D. C. Thomas, S. Preston-Martin, M. L. Rallison, R. D. Lloyd and W. Stevens, A cohort study of thyroid disease in relation to fallout from nuclear weapons testing. J. Am. Med. Assoc. 270, 2076-2082 (1993).
20. J. L. Lyon, S. C. Alder, M. B. Stone, A. Scholl, J. C. Reading, R. Holubkov, X. Sheng, G. L. White, Jr., K. T. Hegmann and A. W. Meikle, Thyroid disease associated with exposure to the Nevada nuclear weapons test site radiation: A reevaluation based on corrected dosimetry and examination data. Epidemiology 17, 604-614 (2006).
21. S. Davis, K. J. Kopecky, T. E. Hamilton and L. Onstad, Thyroid neoplasia, autoimmune thyroiditis, and hypothyroidism in persons exposed to iodine 131 from the Hanford nuclear site. J. Am. Med. Assoc. 292, 2600-2613 (2004).
22. S. Davis, K. Kopecky, T. E. Hamilton, L. Onstad, B. King, M. S. Saporito and C. R. Callahan, Hanford Thyroid Disease Study Final Report. Fred Hutchinson Cancer Research Center, Seattle, WA, 2007.
23. V. A. Stezhko, E. E. Buglova, L. I. Danilova, V. M. Drozd, N. A. Krysenko, N. R. Lesnikova, V. F. Minenko, V. A. Ostapenko, S. V. Petrenko and L. B. Zablotska, A cohort study of thyroid cancer and other thyroid diseases after the Chornobyl accident: Objectives, design and methods. Radiat. Res. 161, 481-492 (2004).
24. J. Brunn, U. Block, G. Ruf, I. Bos, W.P. Kunze and P.C. Scriba Volumetric analysis of thyroid lobes by real-time ultrasound [authors' translation]. Dtsch. Med. Wochenschr. 106, 1338-1340 (1981).
25. F. J. T. Dunn, H. E. Crutchfield, R. Gutekunst and A. D. Dunn, Methods for Measuring Iodine in Urine, pp. 18-27. International Council for Control of Iodine Deficiency Disorders, Charlottesville, VA, 1993.
26. I. Likhtarev, A. Bouville, L. Kovgan, N. Luckyanov, P. Voilleque and M. Chepurny, Questionnaire- and measurementbased individual thyroid doses in Ukraine resulting from the Chornobyl nuclear reactor accident. Radiat. Res. 166, 271-286 (2006).
27. I. Likhtarov, L. Kovgan, S. Vavilov, M. Chepurny, E. Ron, J. Lubin, A. Bouville, N. Tronko, T. Bogdanova and G. Howe, Post-Chernobyl thyroid cancers in Ukraine. Report 2: Risk analysis. Radiat. Res. 166, 375-386 (2006).
28. UNSCEAR, Sources and Effects of Ionizing Radiation, pp. 453- 487. United Nations, New York, 2000.
29. UNSCEAR, Sources and Effects of Ionizing Radiation. United Nations, New York, 1998.
30. H. Akaike, A new look at the statistical model identification. IEEE Trans. Automatic Control 19, 716-723 (1974).
31. R Development Core Team, R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, 2005.
32. D. L. Preston, J. H. Lubin, D. A. Pierce and M. E. McConney, EPICURE. Hirosoft Corporation, Seattle, WA, 1993.
33. M. Imaizumi, T. Usa, T. Tominaga, K. Neriishi, M. Akahoshi, E. Nakashima, K. Ashizawa, A. Hida, M. Soda and K. Eguchi, Radiation dose-response relationships for thyroid nodules and autoimmune thyroid diseases in Hiroshima and Nagasaki atomic bomb survivors 55-58 years after radiation exposure. J. Am. Med. Assoc. 295, 1011-1022 (2006).
34. D. A. Koutras, Subclinical hyperthyroidism. Thyroid 9, 311-315 (1999).
35. D. K. Shrier and K. D. Burman, Subclinical hyperthyroidism: Controversies in management. Am. Fam. Physician 65, 431-438 (2002).
36. C. Kirkegaard and J. Faber, The role of thyroid hormones in depression. Eur. J. Endocrinol. 138, 1-9 (1998).
37. L. Vila, M. Serra-Prat, E. Palomera, R. Casamitjana, A. de Castro, G. Legaz, C. Barrionueva, A-J. Garcia, S. Lal-Trehan and M. Puig-Domingo, Reference values for thyroid function tests in pregnant women living in Catalonia, Spain. Thyroid 20, 221-225 (2010).
38. J. G. Hollowell, N. M. Staehling, W. D. Flanders, W. H. Hanson, E. G. Gunter, C. A. Spencer and L. E. Braverman, Serum TSH, T4, and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J. Clin. Endocrinol. Metab. 87, 489-499 (2002).
39. Y. Li, A. Guolo, F. O. Hoffman and R. J. Carroll, Shared uncertainty in measurement error problems, with application to Nevada Test Site fallout data. Biometrics 63, 1226-1236 (2007).