Thyroid neoplasia, autoimmune thyroiditis, and hypothyroidism in persons exposed to iodine 131 from the Hanford Nuclear Site

JAMA

Volumn 292, Issue 21, 2004, Pages 2600-2613

  Davis, Scott ^a,b   Kopecky, Kenneth J ^a,c   Hamilton, Thomas E ^a,d   Onstad, Lynn ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b Department of Pediatrics   (United States)

^c Sch of Pub Hlth and Comm Med

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IODINE 131;

AIR POLLUTION; ANAMNESIS; ARTICLE; ATOMIC WARFARE; BIRTH; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; DIET; EXPOSURE; FEMALE; FOLLOW UP; HASHIMOTO DISEASE; HUMAN; HUMAN TISSUE; HYPOTHYROIDISM; INCIDENCE; INTERVIEW; MAJOR CLINICAL STUDY; MALE; NEEDLE BIOPSY; PEDIATRICS; PHYSICAL EXAMINATION; PRIORITY JOURNAL; RADIATION DOSE; RETROSPECTIVE STUDY; SAMPLING; THYROID CARCINOMA; THYROID DISEASE; THYROID NODULE; THYROID TUMOR; ULTRASOUND; UNITED STATES;

EID: 9644291657     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.292.21.2600     Document Type: Article

References (71)

1. Heeb CM, Gydesen SP, Simpson JC, Bates DJ. Reconstruction of radionuclide releases from the Hanford Site, 1944-1972. Health Phys. 1996;71:545-555.
2. 131I atmospheric releases from the Hanford site. Health Phys. 2002;83:204-226.
3. Dobyns BM, Sheline GE, Workman JB, Tompkins EA, McConahey WM, Becker DV, Malignant and benign neoplasms of the thyroid in patients treated for hyperthyroidism: a report of the Cooperative Thyrotoxicosis Therapy Follow-up Study. J Clin Endocrinol Metab. 1974;38:976-998.
4. Holm LE, Dahlquist I, Israelsson A, Lundell G. Malignant thyroid tumors after I-131 therapy. N Engl J Med. 1980;303:188-191.
5. Holm LE. Malignant disease following iodine-131 therapy in Sweden. In: Boice JD Jr, Fraumeni JF Jr, eds. Radiation Carcinogenesis: Epidemiology and Biologic Significance. New York, NY: Raven Press; 1984:263-271.
6. Safa AM, Schumacker OP, Rodrigues-Antunez A. Long-term follow-up results in children and adolescents treated with radioactive iodine (I-131) for hyperthyroidism. N Engl J Med. 1975;292:167-171.
7. Ron E, Doody MM, Becker DV, et al. Cancer mortality following treatment for adult hyperthyroidism. JAMA. 1998;280:347-355.
8. Franklyn JA, Maisonneuve P, Sheppard M, Betteridge J, Boyle P. Cancer incidence and mortality after radioiodine treatment for hyperthyroidism: a population-based cohort study. Lancet. 1999;353:2111-2115.
9. Holm LE, Lundell G, Wallinder G. Incidence of malignant thyroid tumors in humans after exposure to diagnostic doses of iodine-131, I: retrospective cohort study. J Natl Cancer Inst. 1980;64:1055-1059.
10. Holm LE, Eklund G, Lundel G. Incidence of malignant tumors in humans after exposure to diagnostic doses of iodine-131, II: estimation of thyroid gland size, thyroid radiation dose, and predicted versus observed number of malignant thyroid tumors. J Natl Cancer Inst. 1980;65:1221-1224.
11. Hall P, Mattson A, Boice JD Jr. Thyroid cancer after diagnostic administration of iodine-131. Radiat Res. 1996;145:86-92.
12. Conard RA, Paglia DE, Larsen PR, et al. Review of Medical Findings in a Marshallese Population 26 Years After Accidental Exposure to Radioactive Fallout. Upton, NY: Brookhaven National Laboratory; 1980. US Dept of Energy publication (BNL) 51-261.
13. Hamilton TE, van Belle G, LoGerfo JP. Thyroid neoplasia in Marshall Islanders exposed to nuclear fallout. JAMA. 1987;258:629-636.
14. Kerber RA, Till JE, Simon SL, et al. A cohort study of thyroid disease in relation to fallout from nuclear weapons testing. JAMA. 1993;270:2076-2082.
15. United Nations Scientific Committee on the Effects of Atomic Radiation. Sources and Effects of Ionizing Radiation: Vol 2: Effects. New York, NY: United Nations; 2000.
16. Moysich KB, Menezes RJ, Michalek AM. Chernobyl-related ionizing radiation exposure and cancer risk: an epidemiological review. Lancet Oncol. 2002;3:269-279.
17. Nagataki S, Shibata Y, Inoue S, Yokoyama N, Izumi M, Shimaoka K. Thyroid diseases among atomic bomb survivors in Nagasaki. JAMA. 1994;272:364-370.
18. Pacini F, Vorontsova T, Molinaro E, et al. Prevalence of thyroid autoantibodies in children and adolescents from Belarus exposed to the Chernobyl radioactive fallout. Lancet. 1998;352:763-766.
19. Davis S, Kopecky KJ, Hamilton TE, et al. Hanford Thyroid Disease Study final report. 2002. Available at: http://www.cdc.gov/nceh/radiation/hanford /htdsweb/. Accessed February 15, 2004.
20. Thompson DE, Mabuchi K, Ron E, et al. Cancer incidence in atomic bomb survivors, II: solid tumors. Radiat Res. 1994;137:S17-S67.
21. National Council on Radiation Protection and Measurements. Induction of Thyroid Cancer by Ionizing Radiation. Washington, DC: National Academy Press; 1985. Report 80.
22. Shore RE, Albert RE, Pasternack BS. Follow-up study of patients treated by x-ray epilation for tinea capitis: resurvey for post-treatment illness and mortality experience. Arch Environ Health. 1976;31:21-28.
23. Shore RE, Woodward ED, Hempleman LH. Radiation-induced thyroid cancer. In: Boice JD Jr, Fraumeni JF Jr, eds. Radiation Carcinogenesis: Epidemiology and Biologic Significance. New York, NY: Raven Press; 1984:131-137.
24. Sikov MR. Effect of age on the iodine-131 metabolism and the radiation sensitivity of the rat thyroid. Radiat Res. 1969;38:449-459.
25. Book SA, McNeill DA, Spangler WL. Age and its influence on effects of iodine-131 in guinea pig thyroid glands. Radiat Res. 1980;81:254-261.
26. Christov K. Radiation-induced thyroid tumors in infant rats. Radiat Res. 1978;73:330-339.
27. Hanford Environmental Dose Reconstruction Project. Draft Air Pathway Report. Richland, Wash: Battelle Pacific Northwest Laboratories; 1990. PNL-7412 HEDR.
28. Farris WT, Napier BA, Ikenberry TA, Shipler DB. Radiation doses from Hanford Site releases to the atmosphere and the Columbia River. Health Phys. 1996;71:588-601.
29. Schlinkert RT, Van Heerden JA, Goellner JR, et al. Factors that predict malignant thyroid lesions when fine-needle aspiration is "suspicious for follicular neoplasm." Mayo Clin Proc. 1997;72:913-916.
30. Tuttle RM, Lemar H, Burch HB. Clinical features associated with an increased risk of thyroid malignancy in patients with follicular neopiasia by fine-needle aspiration. Thyroid. 1998;8:377-383.
31. Raber W, Kaserer K, Niederle B, et al. Risk factors for malignancy of thyroid nodules initially identified as follicular neoplasia by fine-needle aspiration: results of a prospective study of one hundred twenty patients. Thyroid. 2000;10:709-712.
32. Kopecky KJ, Davis S, Hamilton TE, et al. Estimation of thyroid radiation doses for the Hanford Thyroid Disease Study: results and implications for statistical power of the epidemiological analyses. Health Phys. 2004;87:15-32.
33. Shipler DB, Napier BA, Farris WT, Freshley MD. Hanford Environmental Dose Reconstruction Project - an overview. Health Phys. 1996;71:532-544.
34. National Cancer Institute. Estimated exposures and thyroid doses received by the American people from iodine-131 in fallout following Nevada atmospheric nuclear bomb tests. 1997. Available at: http://rex.nci .nih.gov/massmedia/ Fallout/index.html. Accessed October 12, 1998.
35. Duffy BJ Jr, Fitzgerald PJ. Thyroid cancer in childhood and adolescence: report on 28 cases. J Clin Endocrinol. 1950;10:1296-1308.
36. Clark DE. Association of irradiation with cancer of the thyroid in children and adolescents. JAMA. 1955;159:1007-1009.
37. Simpson CL, Hemplemann LH, Fuller LM. Neoplasia in children treated with x-rays in infancy for thymic enlargement. Radiology. 1955;64:840-845.
38. Beach SA, Dolphin GW. A study of the relationship between x-ray dose delivered to the thyroids of children and the subsequent development of malignant tumors. Phys Med Biol. 1962;6:538-598.
39. Kaplan MM, Garnick MB, Gelber R, et al. Risk factors for thyroid abnormalities after neck irradiation for childhood cancer. Am J Med. 1983;74:272-280.
40. Ron E, Modan B. Thyroid and other neoplasms following childhood scalp irradiation. In: Boice JD Jr, Fraumeni JF Jr, eds. Radiation Carcinogenesis: Epidemiology and Biologic Significance. New York, NY: Raven Press; 1984:139-151.
41. Schneider AB, Shore-Freeman E, Ryo U, Bekerman C, Favus M, Pinsky S. Radiation-induced tumors of the head and neck following childhood irradiation: prospective studies. Medicine. 1985;64:1-15.
42. Schneider AB, Recant W, Pinskly SM, Ryo UY, Bekerman C, Shore-Freedman E. Radiation-induced thyroid carcinoma: clinical course and results of therapy in 296 patients. Ann Intern Med. 1986;105:405-412.
43. Shore RE, Hildreth N, Dvoretsky P, Pasternack B, Andresen E. Benign thyroid adenomas among persons x-irradiated in infancy for enlarged thymus glands. Radiat Res. 1993;134:217-223.
44. Ron E, Modan B, Preston D, Alfandary E, Stovall M, Boice JD. Thyroid neoplasia following low-dose radiation in childhood. Radiat Res. 1989;120:516-531.
45. Pottern LM, Kaplan MM, Larsen PR, et al. Thyroid nodularity after childhood irradiation for lymphoid hyperplasia: a comparison of questionnaire and clinical findings. J Clin Epidemiol. 1990;43:449-460.
46. Schneider AB, Ron E, Lubin J, Stovall M, Gierlowski TC. Dose-response relationships for radiation-induced thyroid cancer and thyroid nodules: evidence for the prolonged effects of radiation on the thyroid. J Clin Endocrinol Metab. 1993;77:362-369.
47. Prentice RL, Kato H, Yoshimoto K, Mason M. Radiation exposure and thyroid cancer incidence among Hiroshima and Nagasaki residents. Natl Cancer Inst Monogr. 1982;62:207-212.
48. Ron E, Lubin JH, Shore RE, et al. Thyroid cancer after exposure to external radiation: a pooled analysis of seven studies. Radiat Res. 1995;141:259-277.
49. Hahn K, Schnell-Inderst P, Grosche B, Holm LE. Thyroid cancer after diagnostic administration of iodine-131 in childhood. Radiat Res. 2001;156:61-70.
50. Dickman PW, Holm LE, Lundell G, Boice JD, Hall P. Thyroid cancer risk after thyroid examination with I-131: a population-based cohort study in Sweden. Int J Cancer. 2003;106:580-587.
51. Rallison ML, Dobyns BM, Keating FR, Rall JE, Tyler FH. Thyroid diseases in children: a survey of subjects potentially exposed to fallout radiation. Am J Med. 1974;56:457-463.
52. Rallison ML, Dobyns BM, Keating FR, Rall JE, Tyler FH. Thyroid nodularity in children. JAMA. 1975;233:1069-1072.
53. Stevens W, Till JE, Thomas DC, et al. Report of a Cohort Study of Thyroid Disease and Radioactive Fallout From the Nevada Test Site. Bethesda, Md: National Cancer Institute; July 1992. Contract NN01-CO-23917.
54. James RA. Estimate of Radiation Dose to Thyroids of the Rongelap Children Following the BRAVO Event. Livermore: University of California Radiation Laboratory; 1964. US Dept of Energy publication 12-273.
55. Lessard E, Miltenberger R, Conard R, et al. Thyroid Absorbed Dose for People at Rongelap, Utrik, and Sifo on March 1, 1954. Upton, NY: Brookhaven National Laboratory; 1985. US Dept of Energy publication BNL 51-882.
56. Davis S, Stepanenko V, Rivkind N, et al. Risk of thyroid cancer in the Bryansk Oblast of the Russian Federation following the Chernobyl Power Station accident. Radiat Res. 2004;162:241-248.
57. Astakhova LN, Anspaugh LR, Beebe GW, et al. Chernobyl-related thyroid cancer in children of Belarus: a case-control study. Radiat Res. 1998;150:349-356.
58. Eheman CR, Garbe P, Tuttle RM. Autoimmune thyroid disease associated with environmental thyroidal irradiation. Thyroid. 2003;13:453-464.
59. Akiyama M. Late effects of radiation on the human immune system: an overview of immune response among the atomic bomb survivors. Int J Radiat Biol. 1995;68:497-508.
60. Yoshimoto Y, Ezaki H, Etoh R, Hiraoka T, Akiba S. Prevalence rate of thyroid diseases among autopsy cases of the atomic bomb survivors in Hiroshima, 1951-1985. Radiat Res. 1995;141:278-286.
61. Kaplan MM, Boice JD Jr, Ames DB, Rosenstein M. Thyroid, parathyroid, and salivary gland evaluations in patients exposed to multiple fluoroscopic examinations during tuberculosis therapy: a pilot study. J Clin Endocrinol Metab. 1988;66:376-382.
62. Hancock SL, Cox RS, McDougall IR. Thyroid diseases after treatment of Hodgkin's disease. N Engl J Med. 1991;325:599-605.
63. Degroot LJ, Reilly M, Pinnameneni K, Refetoff S. Retrospective and prospective study of radiation-induced thyroid disease. Am J Med. 1983;74:852-862.
64. Larsen PR, Conard RA, Knudsen KD, et al. Thyroid hypofunction after exposure to fallout from a hydrogen bomb explosion. JAMA. 1982;247:1571-1575.
65. Vermiglio F, Castagna MG, Volnova E, et al. Post-Chernobyl increased prevalence of humoral thyroid autoimmunity in children and adolescents from a moderately iodine-deficient area in Russia. Thyroid. 1999;9:781-786.
66. Yamashita S, Shibata Y, eds. Chernobyl: a decade. In: Proceedings of the Fifth Chernobyl Sasakawa Medical Cooperation Symposium. Amsterdam, the Netherlands: Elsevier Science BV; 1997.
67. Vanderpump MP, Tunbridge WM, French JM, et al. The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey. Clin Endocrinol (Oxf). 1995;43:55-68.
68. 4, and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab. 2002;87:489-499.
69. Geul KW, van Sluisveld ILL, Grobbee DE, et al. The importance of thyroid microsomal antibodies in the development of elevated serum TSH in middle-aged women: associations with serum lipids. Clin Endocrinol (Oxf). 1993;39:275-280.
70. Tomer Y. Anti-thyroglobulin autoantibodies in autoimmune thyroid diseases: cross-reactive or pathogenic? Clin Immunol Immunopathol. 1997;82:3-11.
71. International Classification of Diseases, Ninth Revision (ICD-9) World Health Organization. Geneva, Switzerland: World Health Organization; 1977.