-
1
-
-
0032909576
-
Preface to molecular and cellular themes in cancer research
-
Hall PA, Lane DP,. Preface to molecular and cellular themes in cancer research. J Pathol 1999; 187: 2-3.
-
(1999)
J Pathol
, vol.187
, pp. 2-3
-
-
Hall, P.A.1
Lane, D.P.2
-
2
-
-
13644258036
-
Molecular and cellular themes in cancer research: II
-
Hall PA, Lowe SW,. Molecular and cellular themes in cancer research: II. J Pathol 2005; 205: 121-122.
-
(2005)
J Pathol
, vol.205
, pp. 121-122
-
-
Hall, P.A.1
Lowe, S.W.2
-
3
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, et al., Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001; 344: 1031-1037.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
4
-
-
20844433223
-
Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: Randomised trial
-
Verweij J, Casali PG, Zalcberg J, et al., Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial. Lancet 2004; 364: 1127-1134.
-
(2004)
Lancet
, vol.364
, pp. 1127-1134
-
-
Verweij, J.1
Casali, P.G.2
Zalcberg, J.3
-
5
-
-
39149127634
-
Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033
-
Blanke CD, Rankin C, Demetri GD, et al., Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033. J Clin Oncol 2008; 26: 626-632.
-
(2008)
J Clin Oncol
, vol.26
, pp. 626-632
-
-
Blanke, C.D.1
Rankin, C.2
Demetri, G.D.3
-
6
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, et al., Mutations of the BRAF gene in human cancer. Nature 2002; 417: 949-954.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
7
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from 'never smokers' and correlate with sensitivity of tumors to gefitinib (Iressa) and erlotinib (Tarceva)
-
Pao W, Miller V, Zakowski MF, et al., EGF receptor gene mutations are common in lung cancers from 'never smokers' and correlate with sensitivity of tumors to gefitinib (Iressa) and erlotinib (Tarceva). Proc Natl Acad Sci USA 2004; 101: 13306-13311.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.F.3
-
8
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al., Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
9
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al., EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304: 1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
10
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, et al., Gefitinib or carboplatin- paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009; 361: 947-957.
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
-
11
-
-
48249114422
-
EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
-
Koivunen JP, Mermel C, Zejnullahu K, et al., EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 2008; 14: 4275-4283.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4275-4283
-
-
Koivunen, J.P.1
Mermel, C.2
Zejnullahu, K.3
-
12
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty KT, Puzanov I, Kim KB, et al., Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med 2010; 363: 809-819.
-
(2010)
N Engl J Med
, vol.363
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
-
13
-
-
78650034175
-
Genetically-informed lung cancer medicine
-
Pao W, Iafrate AJ, Su Z,. Genetically-informed lung cancer medicine. J Pathol 2011; 223: 231-241.
-
(2011)
J Pathol
, vol.223
, pp. 231-241
-
-
Pao, W.1
Iafrate, A.J.2
Su, Z.3
-
14
-
-
78650015822
-
A new era: Melanoma genetics and therapeutics
-
Ko JM, Fisher DE,. A new era: melanoma genetics and therapeutics. J Pathol 2011; 223: 242-251.
-
(2011)
J Pathol
, vol.223
, pp. 242-251
-
-
Ko, J.M.1
Fisher, D.E.2
-
15
-
-
78650026316
-
KRAS and BRAF: Drug targets and predictive biomarkers
-
Vakiani E, Solit DB,. KRAS and BRAF: Drug targets and predictive biomarkers. J Pathol 2011; 223: 220-230.
-
(2011)
J Pathol
, vol.223
, pp. 220-230
-
-
Vakiani, E.1
Solit, D.B.2
-
16
-
-
78650003580
-
The GIST paradigm: Lessons for other kinase-driven cancers
-
Antonescu CR,. The GIST paradigm: lessons for other kinase-driven cancers. J Pathol 2011; 223: 252-262.
-
(2011)
J Pathol
, vol.223
, pp. 252-262
-
-
Antonescu, C.R.1
-
17
-
-
78650001387
-
Clinical cancer genomics: How soon is now?
-
Taylor BS, Ladanyi M,. Clinical cancer genomics: how soon is now? J Pathol 2011; 223: 319-327.
-
(2011)
J Pathol
, vol.223
, pp. 319-327
-
-
Taylor, B.S.1
Ladanyi, M.2
-
19
-
-
0032931517
-
The p53 pathway
-
Prives C, Hall PA,. The p53 pathway. J Pathol 1999; 187: 112-126.
-
(1999)
J Pathol
, vol.187
, pp. 112-126
-
-
Prives, C.1
Hall, P.A.2
-
20
-
-
13644264337
-
What have animal models taught us about the p53 pathway?
-
Lozano G, Zambetti GP,. What have animal models taught us about the p53 pathway? J Pathol 2005; 205: 206-220.
-
(2005)
J Pathol
, vol.205
, pp. 206-220
-
-
Lozano, G.1
Zambetti, G.P.2
-
21
-
-
78650018910
-
Regulation of tissue- and stimulus-specific cell fate decisions by p53 in vivo
-
Jackson JG, Post SM, Lozano G,. Regulation of tissue- and stimulus-specific cell fate decisions by p53 in vivo. J Pathol 2011; 223: 127-137.
-
(2011)
J Pathol
, vol.223
, pp. 127-137
-
-
Jackson, J.G.1
Post, S.M.2
Lozano, G.3
-
22
-
-
78650015522
-
The role of mutant p53 in human cancer
-
Goh AM, Coffill CR, Lane DP,. The role of mutant p53 in human cancer. J Pathol 2011; 223: 116-126.
-
(2011)
J Pathol
, vol.223
, pp. 116-126
-
-
Goh, A.M.1
Coffill, C.R.2
Lane, D.P.3
-
23
-
-
0032954092
-
Insights into cancer from transgenic mouse models
-
Macleod KF, Jacks T,. Insights into cancer from transgenic mouse models. J Pathol 1999; 187: 43-60.
-
(1999)
J Pathol
, vol.187
, pp. 43-60
-
-
MacLeod, K.F.1
Jacks, T.2
-
24
-
-
13644266446
-
New approaches for modelling cancer mechanisms in the mouse
-
Maddison K, Clarke AR,. New approaches for modelling cancer mechanisms in the mouse. J Pathol 2005; 205: 181-193.
-
(2005)
J Pathol
, vol.205
, pp. 181-193
-
-
Maddison, K.1
Clarke, A.R.2
-
25
-
-
13644251904
-
Advances in imaging mouse tumour models in vivo
-
Lyons SK,. Advances in imaging mouse tumour models in vivo. J Pathol 2005; 205: 194-205.
-
(2005)
J Pathol
, vol.205
, pp. 194-205
-
-
Lyons, S.K.1
-
26
-
-
78650027929
-
Haploinsufficiency: A driving force in cancer
-
Berger AH, Pandolfi PP,. Haploinsufficiency: a driving force in cancer. J Pathol 2011; 223: 138-147.
-
(2011)
J Pathol
, vol.223
, pp. 138-147
-
-
Berger, A.H.1
Pandolfi, P.P.2
-
27
-
-
0032907527
-
Molecular epidemiology of human cancer risk: Gene-environment interactions and p53 mutation spectrum in human lung cancer
-
Bennett WP, Hussain SP, Vahakangas KH, et al., Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer. J Pathol 1999; 187: 8-18.
-
(1999)
J Pathol
, vol.187
, pp. 8-18
-
-
Bennett, W.P.1
Hussain, S.P.2
Vahakangas, K.H.3
-
28
-
-
13644259990
-
Molecular evolution of breast cancer
-
Simpson PT, Reis-Filho JS, Gale T, et al., Molecular evolution of breast cancer. J Pathol 2005; 205: 248-254.
-
(2005)
J Pathol
, vol.205
, pp. 248-254
-
-
Simpson, P.T.1
Reis-Filho, J.S.2
Gale, T.3
-
29
-
-
13644269831
-
Gastrointestinal lymphoma: Where morphology meets molecular biology
-
Isaacson PG, Du MQ,. Gastrointestinal lymphoma: where morphology meets molecular biology. J Pathol 2005; 205: 255-274.
-
(2005)
J Pathol
, vol.205
, pp. 255-274
-
-
Isaacson, P.G.1
Du, M.Q.2
-
30
-
-
78649991073
-
Notch signalling in T cell lymphoblastic leukaemia/lymphoma and other haematological malignancies
-
Aster JC, Blacklow SC, Pear WS,. Notch signalling in T cell lymphoblastic leukaemia/lymphoma and other haematological malignancies. J Pathol 2011; 223: 263-274.
-
(2011)
J Pathol
, vol.223
, pp. 263-274
-
-
Aster, J.C.1
Blacklow, S.C.2
Pear, W.S.3
-
31
-
-
78649995921
-
The molecular background of aggressive B-cell lymphomas as a basis for targeted therapy
-
De Jong D, Balagué Ponz O,. The molecular background of aggressive B-cell lymphomas as a basis for targeted therapy. J Pathol 2011; 223: 275-283.
-
(2011)
J Pathol
, vol.223
, pp. 275-283
-
-
De Jong, D.1
Balagué Ponz, O.2
-
32
-
-
78650017792
-
The complexity of pancreatic ductal cancers and multidimensional strategies for therapeutic targeting
-
Kern SE, Shi C, Hruban RH,. The complexity of pancreatic ductal cancers and multidimensional strategies for therapeutic targeting. J Pathol 2011; 223: 296-307.
-
(2011)
J Pathol
, vol.223
, pp. 296-307
-
-
Kern, S.E.1
Shi, C.2
Hruban, R.H.3
-
33
-
-
78649998496
-
Metabolic alterations and targeted therapies in prostate cancer
-
Flavin R, Zadra G, Loda M,. Metabolic alterations and targeted therapies in prostate cancer. J Pathol 2011; 223: 284-295.
-
(2011)
J Pathol
, vol.223
, pp. 284-295
-
-
Flavin, R.1
Zadra, G.2
Loda, M.3
-
34
-
-
78650028237
-
The molecular pathology of breast cancer progression
-
Bombonati A, Sgroi DC,. The molecular pathology of breast cancer progression. J Pathol 2011; 223: 308-318.
-
(2011)
J Pathol
, vol.223
, pp. 308-318
-
-
Bombonati, A.1
Sgroi, D.C.2
-
35
-
-
78650001948
-
Tracing the origins of metastasis
-
Nguyen DX,. Tracing the origins of metastasis. J Pathol 2011; 223: 196-205.
-
(2011)
J Pathol
, vol.223
, pp. 196-205
-
-
Nguyen, D.X.1
-
36
-
-
78649997911
-
Jekyll and Hyde: The role of the microenvironment on the progression of cancer
-
Allen M, Jones JL,. Jekyll and Hyde: the role of the microenvironment on the progression of cancer. J Pathol 2011; 223: 163-177.
-
(2011)
J Pathol
, vol.223
, pp. 163-177
-
-
Allen, M.1
Jones, J.L.2
-
37
-
-
78649981811
-
Cell death in the neighbourhood: Direct microenvironmental effects of apoptosis in normal and neoplastic tissues
-
Gregory CD, Pound CD,. Cell death in the neighbourhood: direct microenvironmental effects of apoptosis in normal and neoplastic tissues. J Pathol 2011; 223: 178-195.
-
(2011)
J Pathol
, vol.223
, pp. 178-195
-
-
Gregory, C.D.1
Pound, C.D.2
-
38
-
-
78649982907
-
The dynamic roles of TGF-β in cancer
-
ten Dijke P,. The dynamic roles of TGF-β in cancer. J Pathol 2011; 223: 206-219.
-
(2011)
J Pathol
, vol.223
, pp. 206-219
-
-
Ten Dijke, P.1
|