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Volumn 223, Issue 2, 2011, Pages 275-283

The molecular background of aggressive B cell lymphomas as a basis for targeted therapy

Author keywords

B cell; Burkitt; diffuse; gene; genetic; large cell; lymphoma; therapy

Indexed keywords

B CELL LYMPHOMA; BURKITT LYMPHOMA; CHROMOSOME ABERRATION; GENE EXPRESSION; HUMAN; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; REVIEW;

EID: 78649995921     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2807     Document Type: Review
Times cited : (21)

References (68)
  • 2
    • 77958155431 scopus 로고    scopus 로고
    • Using functional genetics to understand breast cancer biology
    • Ashworth A, Bernards R,. Using functional genetics to understand breast cancer biology. Cold Spring Harb Perspect Biol 2010; 2: a003327.
    • (2010) Cold Spring Harb Perspect Biol , vol.2
    • Ashworth, A.1    Bernards, R.2
  • 3
    • 77950930066 scopus 로고    scopus 로고
    • It's diagnostics, stupid
    • Bernards R,. It's diagnostics, stupid. Cell 2010; 141: 13-17.
    • (2010) Cell , vol.141 , pp. 13-17
    • Bernards, R.1
  • 4
    • 77955019276 scopus 로고    scopus 로고
    • Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: A proof-of-concept trial
    • Tutt A, Robson M, Garber JE, et al., Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet 2010; 376: 235-244.
    • (2010) Lancet , vol.376 , pp. 235-244
    • Tutt, A.1    Robson, M.2    Garber, J.E.3
  • 5
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, et al., Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000; 403: 503-511.
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3
  • 6
    • 0037142053 scopus 로고    scopus 로고
    • The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma
    • Rosenwald A, Wright G, Chan WC, et al., The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N Engl J Med 2002; 346: 1937-1947.
    • (2002) N Engl J Med , vol.346 , pp. 1937-1947
    • Rosenwald, A.1    Wright, G.2    Chan, W.C.3
  • 7
    • 10744228934 scopus 로고    scopus 로고
    • The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma
    • Savage KJ, Monti S, Kutok JL, et al., The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma. Blood 2003; 2: 3871-3879.
    • (2003) Blood , vol.2 , pp. 3871-3879
    • Savage, K.J.1    Monti, S.2    Kutok, J.L.3
  • 8
    • 0141672946 scopus 로고    scopus 로고
    • Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma
    • Rosenwald A, Wright G, Leroy K, et al., Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma. J Exp Med 2003; 198: 851-862.
    • (2003) J Exp Med , vol.198 , pp. 851-862
    • Rosenwald, A.1    Wright, G.2    Leroy, K.3
  • 9
    • 84880633093 scopus 로고    scopus 로고
    • Commentary on the WHO classification of tumors of lymphoid tissues (2008): 'Gray zone' lymphomas overlapping with Burkitt lymphoma or classical Hodgkin lymphoma
    • Hasserjian RP, Ott G, Elenitoba-Johnson KS, et al., Commentary on the WHO classification of tumors of lymphoid tissues (2008): 'Gray zone' lymphomas overlapping with Burkitt lymphoma or classical Hodgkin lymphoma. J Hematopathol 2009; 2: 89-95.
    • (2009) J Hematopathol , vol.2 , pp. 89-95
    • Hasserjian, R.P.1    Ott, G.2    Elenitoba-Johnson, K.S.3
  • 10
    • 78649681227 scopus 로고    scopus 로고
    • Gray zones around diffuse large B cell lymphoma. Conclusions based on the workshop of the XIV meeting of the European Association for Hematopathology and the Society of Hematopathology in Bordeaux, France
    • Quintanilla-Martinez L, de Jong D, de Mascarel A, et al., Gray zones around diffuse large B cell lymphoma. Conclusions based on the workshop of the XIV meeting of the European Association for Hematopathology and the Society of Hematopathology in Bordeaux, France. J Hematopathol 2009; 2: 211-236.
    • (2009) J Hematopathol , vol.2 , pp. 211-236
    • Quintanilla-Martinez, L.1    De Jong, D.2    De Mascarel, A.3
  • 11
    • 0035905313 scopus 로고    scopus 로고
    • Constitutive nuclear factor κb activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells
    • Davis RE, Brown KD, Siebenlist U, et al., Constitutive nuclear factor κB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells. J Exp Med 2001; 194: 1861-1874.
    • (2001) J Exp Med , vol.194 , pp. 1861-1874
    • Davis, R.E.1    Brown, K.D.2    Siebenlist, U.3
  • 12
    • 33947586159 scopus 로고    scopus 로고
    • Aberrant NF-κB signaling in lymphoma: Mechanisms, consequences, and therapeutic implications
    • Jost PJ, Ruland J,. Aberrant NF-κB signaling in lymphoma: mechanisms, consequences, and therapeutic implications. Blood 2007; 109: 2700-2707.
    • (2007) Blood , vol.109 , pp. 2700-2707
    • Jost, P.J.1    Ruland, J.2
  • 13
    • 19944428834 scopus 로고    scopus 로고
    • Small molecule inhibitors of IκB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling
    • Lam LT, Davis RE, Pierce J, et al., Small molecule inhibitors of IκB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling. Clin Can Res 2005; 11: 28-40.
    • (2005) Clin Can Res , vol.11 , pp. 28-40
    • Lam, L.T.1    Davis, R.E.2    Pierce, J.3
  • 14
    • 33645306041 scopus 로고    scopus 로고
    • A loss-of-function RNA interference screen for molecular targets in cancer
    • Ngo VN, Davis RE, Lamy L, et al., A loss-of-function RNA interference screen for molecular targets in cancer. Nature 2006; 441: 106-110.
    • (2006) Nature , vol.441 , pp. 106-110
    • Ngo, V.N.1    Davis, R.E.2    Lamy, L.3
  • 15
    • 41149136296 scopus 로고    scopus 로고
    • Oncogenic CARD11 mutations in human diffuse large B-cell lymphoma
    • Lenz G, Davis RE, Ngo VN, et al., Oncogenic CARD11 mutations in human diffuse large B-cell lymphoma. Science 2008; 319: 1676-1679.
    • (2008) Science , vol.319 , pp. 1676-1679
    • Lenz, G.1    Davis, R.E.2    Ngo, V.N.3
  • 16
    • 66649127621 scopus 로고    scopus 로고
    • Mutations in multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma
    • Compagno M, Lim WK, Grunn A, et al., Mutations in multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma. Nature 2009; 459: 717-721.
    • (2009) Nature , vol.459 , pp. 717-721
    • Compagno, M.1    Lim, W.K.2    Grunn, A.3
  • 17
    • 70350504882 scopus 로고    scopus 로고
    • TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas
    • Honma K, Tsuzuki S, Nakagawa MY, et al., TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas. Blood 2009; 114: 2467-2475.
    • (2009) Blood , vol.114 , pp. 2467-2475
    • Honma, K.1    Tsuzuki, S.2    Nakagawa, M.Y.3
  • 18
    • 73849145729 scopus 로고    scopus 로고
    • Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
    • Davis RE, Ngo VN, Lenz G, et al., Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma. Nature 2010; 463: 88-92.
    • (2010) Nature , vol.463 , pp. 88-92
    • Davis, R.E.1    Ngo, V.N.2    Lenz, G.3
  • 19
    • 51649111684 scopus 로고    scopus 로고
    • Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways
    • Lenz G, Wright GW, Emre NC, et al., Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways. Proc Natl Acad Sci USA 2008; 105: 13520-13525.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13520-13525
    • Lenz, G.1    Wright, G.W.2    Emre, N.C.3
  • 20
    • 0032523043 scopus 로고    scopus 로고
    • P16(INK4a) gene inactivation by deletions, mutations, and hypermethylation is associated with transformed and aggressive variants of non-Hodgkin's lymphomas
    • Pinyol M, Cobo F, Bea S, et al., p16(INK4a) gene inactivation by deletions, mutations, and hypermethylation is associated with transformed and aggressive variants of non-Hodgkin's lymphomas. Blood 1998; 91: 2977-2984.
    • (1998) Blood , vol.91 , pp. 2977-2984
    • Pinyol, M.1    Cobo, F.2    Bea, S.3
  • 21
    • 0033899352 scopus 로고    scopus 로고
    • INK4a/ARF locus alterations in human non-Hodgkin's lymphomas mainly occur in tumors with wild-type p53 gene
    • Pinyol M, Hernández L, Martínez A, et al., INK4a/ARF locus alterations in human non-Hodgkin's lymphomas mainly occur in tumors with wild-type p53 gene. Am J Pathol 2000; 156: 1987-1996.
    • (2000) Am J Pathol , vol.156 , pp. 1987-1996
    • Pinyol, M.1    Hernández, L.2    Martínez, A.3
  • 22
    • 23944468557 scopus 로고    scopus 로고
    • Comparison of genome profiles for identification of distinct subgroups of diffuse large B-cell lymphoma
    • Tagawa H, Suguro M, Tsuzuki S, et al., Comparison of genome profiles for identification of distinct subgroups of diffuse large B-cell lymphoma. Blood 2005; 106: 1770-1777.
    • (2005) Blood , vol.106 , pp. 1770-1777
    • Tagawa, H.1    Suguro, M.2    Tsuzuki, S.3
  • 23
    • 67650398258 scopus 로고    scopus 로고
    • Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma
    • Dunleavy K, Pittaluga S, Czuczman MS, et al., Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma. Blood 2009; 113: 6069-6076.
    • (2009) Blood , vol.113 , pp. 6069-6076
    • Dunleavy, K.1    Pittaluga, S.2    Czuczman, M.S.3
  • 24
    • 54349098434 scopus 로고    scopus 로고
    • Molecular signatures define new rational treatment targets in large B-cell lymphoma
    • Shipp MA,. Molecular signatures define new rational treatment targets in large B-cell lymphoma. Hematol Am Soc Hematol Educ Program 2007; 265-269.
    • (2007) Hematol Am Soc Hematol Educ Program , pp. 265-269
    • Shipp, M.A.1
  • 25
    • 0034730186 scopus 로고    scopus 로고
    • Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas
    • Lossos IS, Alizadeh AA, Eisen MB, et al., Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas. Proc Natl Acad Sci USA 2000; 97: 10209-10213.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10209-10213
    • Lossos, I.S.1    Alizadeh, A.A.2    Eisen, M.B.3
  • 26
    • 33947403981 scopus 로고    scopus 로고
    • Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma
    • Lenz G, Nagel I, Siebert R, et al., Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma. J Exp Med 2007; 204: 633-643.
    • (2007) J Exp Med , vol.204 , pp. 633-643
    • Lenz, G.1    Nagel, I.2    Siebert, R.3
  • 27
    • 0036530299 scopus 로고    scopus 로고
    • The t(14; 18) defines a unique subset of diffuse large B-cell lymphoma with a germinal center B-cell gene expression profile
    • Huang JZ, Sanger WG, Greiner TC, et al., The t(14; 18) defines a unique subset of diffuse large B-cell lymphoma with a germinal center B-cell gene expression profile. Blood 2002; 99: 2285-2290.
    • (2002) Blood , vol.99 , pp. 2285-2290
    • Huang, J.Z.1    Sanger, W.G.2    Greiner, T.C.3
  • 28
    • 54049126176 scopus 로고    scopus 로고
    • Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: An international collaborative study
    • Young KH, Leroy K, Møller MB, et al., Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study. Blood 2008; 112: 3088-3098.
    • (2008) Blood , vol.112 , pp. 3088-3098
    • Young, K.H.1    Leroy, K.2    Møller, M.B.3
  • 29
    • 27644488026 scopus 로고    scopus 로고
    • Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression based survival prediction
    • Bea S, Zettl A, Wright G, et al., Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression based survival prediction. Blood 2005; 106: 3183-3190.
    • (2005) Blood , vol.106 , pp. 3183-3190
    • Bea, S.1    Zettl, A.2    Wright, G.3
  • 30
    • 63149129655 scopus 로고    scopus 로고
    • Bcl-2 inhibitors: Targeting mitochondrial apoptotic pathways in cancer therapy
    • Kang MH, Reynolds CP,. Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy. Clin Cancer Res 2009; 15: 1126-1132.
    • (2009) Clin Cancer Res , vol.15 , pp. 1126-1132
    • Kang, M.H.1    Reynolds, C.P.2
  • 31
    • 77955173214 scopus 로고    scopus 로고
    • Targeted treatment and new agents in follicular lymphoma
    • Cheson B,. Targeted treatment and new agents in follicular lymphoma. Int J Hematol 2010; 92: 5-11.
    • (2010) Int J Hematol , vol.92 , pp. 5-11
    • Cheson, B.1
  • 32
    • 68149114040 scopus 로고    scopus 로고
    • Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival and transformation from follicular lymphoma
    • Lawrie CH, Chi J, Taylor S, et al., Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival and transformation from follicular lymphoma. J Cell Mol Med 2009; 13: 1248-1260.
    • (2009) J Cell Mol Med , vol.13 , pp. 1248-1260
    • Lawrie, C.H.1    Chi, J.2    Taylor, S.3
  • 33
    • 0038492517 scopus 로고    scopus 로고
    • A global transcriptional regulatory role for c-MYC in Burkitt's lymphoma cells
    • Li Z, van Calcar S, Qu C, et al., A global transcriptional regulatory role for c-MYC in Burkitt's lymphoma cells. Proc Natl Acad Sci USA 2003; 100: 8164-8168.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8164-8168
    • Li, Z.1    Van Calcar, S.2    Qu, C.3
  • 34
    • 77951681449 scopus 로고    scopus 로고
    • Advances in understanding of MYC-induced lymphomagenesis
    • Klapproth K, Wirth T,. Advances in understanding of MYC-induced lymphomagenesis. Br J Haematol 2010; 149: 484-497.
    • (2010) Br J Haematol , vol.149 , pp. 484-497
    • Klapproth, K.1    Wirth, T.2
  • 35
    • 20444479428 scopus 로고    scopus 로고
    • C-Myc-regulated microRNAs modulate E2F1 expression
    • O'Donnell KA, Wentzel EA, Zeller K, et al., c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005; 435: 839-843.
    • (2005) Nature , vol.435 , pp. 839-843
    • O'Donnell, K.A.1    Wentzel, E.A.2    Zeller, K.3
  • 36
    • 52149105208 scopus 로고    scopus 로고
    • Structure and consequences of IGH switch breakpoints in Burkitt lymphoma
    • Guikema JE, Schuuring E, Kluin PM,. Structure and consequences of IGH switch breakpoints in Burkitt lymphoma. J Natl Cancer Inst Monogr 2008; 39: 32-36.
    • (2008) J Natl Cancer Inst Monogr , vol.39 , pp. 32-36
    • Guikema, J.E.1    Schuuring, E.2    Kluin, P.M.3
  • 37
    • 33746788256 scopus 로고    scopus 로고
    • IGH switch breakpoints in Burkitt lymphoma: Exclusive involvement of noncanonical class switch recombination
    • Guikema JE, de Boer C, Haralambieva E, et al., IGH switch breakpoints in Burkitt lymphoma: exclusive involvement of noncanonical class switch recombination. Genes Chromosomes Cancer 2006; 45: 808-819.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 808-819
    • Guikema, J.E.1    De Boer, C.2    Haralambieva, E.3
  • 38
    • 0036392058 scopus 로고    scopus 로고
    • Role of genetic and epigenetic changes in Burkitt lymphoma
    • Lindström MS, Wiman KG,. Role of genetic and epigenetic changes in Burkitt lymphoma. Semin Cancer Biol 2002; 12: 381-387.
    • (2002) Semin Cancer Biol , vol.12 , pp. 381-387
    • Lindström, M.S.1    Wiman, K.G.2
  • 39
    • 60149087553 scopus 로고    scopus 로고
    • Translocations involving 8q24 in Burkitt lymphoma and other malignant lymphomas - A historical review of cytogenetics in the light of today's knowledge
    • Boerma EJ, Siebert R, Kluin PM, et al., Translocations involving 8q24 in Burkitt lymphoma and other malignant lymphomas-a historical review of cytogenetics in the light of today's knowledge. Leukemia 2009; 23: 225-234.
    • (2009) Leukemia , vol.23 , pp. 225-234
    • Boerma, E.J.1    Siebert, R.2    Kluin, P.M.3
  • 40
    • 34548031172 scopus 로고    scopus 로고
    • Gene-expression analysis identifies novel RBL2/p130 target genes in endemic Burkitt lymphoma cell lines and primary tumors
    • De Falco G, Leucci E, Lenze D, et al., Gene-expression analysis identifies novel RBL2/p130 target genes in endemic Burkitt lymphoma cell lines and primary tumors. Blood 2007; 110: 1301-1307.
    • (2007) Blood , vol.110 , pp. 1301-1307
    • De Falco, G.1    Leucci, E.2    Lenze, D.3
  • 41
    • 57149097456 scopus 로고    scopus 로고
    • MYC translocation-negative classical Burkitt lymphoma cases: An alternative pathogenetic mechanism involving miRNA deregulation
    • Leucci E, Cocco M, Onnis A, et al., MYC translocation-negative classical Burkitt lymphoma cases: an alternative pathogenetic mechanism involving miRNA deregulation. J Pathol 2008; 216: 440-450.
    • (2008) J Pathol , vol.216 , pp. 440-450
    • Leucci, E.1    Cocco, M.2    Onnis, A.3
  • 42
    • 74949127554 scopus 로고    scopus 로고
    • B-cell differentiation in EBV-positive Burkitt lymphoma is impaired at posttranscriptional level by miRNA-altered expression
    • Leucci E, Onnis A, Cocco M, et al., B-cell differentiation in EBV-positive Burkitt lymphoma is impaired at posttranscriptional level by miRNA-altered expression. Int J Cancer 2010; 126: 1316-1326.
    • (2010) Int J Cancer , vol.126 , pp. 1316-1326
    • Leucci, E.1    Onnis, A.2    Cocco, M.3
  • 43
    • 77952730045 scopus 로고    scopus 로고
    • MiRNA profiling in B non-Hodgkin lymphoma: A MYC-related miRNA profile characterizes Burkitt lymphoma
    • Robertus JL, Kluiver J, Weggemans C, et al., MiRNA profiling in B non-Hodgkin lymphoma: a MYC-related miRNA profile characterizes Burkitt lymphoma. Br J Haematol 2010; 149: 896-899.
    • (2010) Br J Haematol , vol.149 , pp. 896-899
    • Robertus, J.L.1    Kluiver, J.2    Weggemans, C.3
  • 44
    • 33847190348 scopus 로고    scopus 로고
    • Mapping of MYC breakpoints in 8q24 rearrangements involving non-immunoglobulin partners in B-cell lymphomas
    • Bertrand P, Bastard C, Maingonnat C, et al., Mapping of MYC breakpoints in 8q24 rearrangements involving non-immunoglobulin partners in B-cell lymphomas. Leukemia 2007; 21: 515-523.
    • (2007) Leukemia , vol.21 , pp. 515-523
    • Bertrand, P.1    Bastard, C.2    Maingonnat, C.3
  • 45
    • 33744960411 scopus 로고    scopus 로고
    • A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling
    • Hummel M, Bentink S, Berger H, et al., A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. N Engl J Med 2006; 254: 2419-2430.
    • (2006) N Engl J Med , vol.254 , pp. 2419-2430
    • Hummel, M.1    Bentink, S.2    Berger, H.3
  • 46
    • 33645279862 scopus 로고    scopus 로고
    • Molecular diagnosis of Burkitt lymphoma
    • Dave SS, Fu K, Wright GW, et al., Molecular diagnosis of Burkitt lymphoma. N Engl J Med 2006; 354: 2431-2442.
    • (2006) N Engl J Med , vol.354 , pp. 2431-2442
    • Dave, S.S.1    Fu, K.2    Wright, G.W.3
  • 47
    • 50849142546 scopus 로고    scopus 로고
    • Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma
    • Salaverria I, Zettl A, Beà S, et al., Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma. Haematologica 2008; 93: 1327-1334.
    • (2008) Haematologica , vol.93 , pp. 1327-1334
    • Salaverria, I.1    Zettl, A.2    Beà, S.3
  • 48
    • 18244397943 scopus 로고    scopus 로고
    • Distinct types of primary cutaneous large B-cell lymphoma identified by gene expression profiling
    • Hoefnagel JJ, Dijkman R, Basso K, et al., Distinct types of primary cutaneous large B-cell lymphoma identified by gene expression profiling. Blood 2005; 105: 3671-3678.
    • (2005) Blood , vol.105 , pp. 3671-3678
    • Hoefnagel, J.J.1    Dijkman, R.2    Basso, K.3
  • 49
    • 33644828132 scopus 로고    scopus 로고
    • Array-based comparative genomic hybridization analysis reveals recurrent chromosomal alterations and prognostic parameters in primary cutaneous large B-cell lymphoma
    • Dijkman R, Tensen CP, Jordanova ES, et al., Array-based comparative genomic hybridization analysis reveals recurrent chromosomal alterations and prognostic parameters in primary cutaneous large B-cell lymphoma. J Clin Oncol 2006; 24: 296-305.
    • (2006) J Clin Oncol , vol.24 , pp. 296-305
    • Dijkman, R.1    Tensen, C.P.2    Jordanova, E.S.3
  • 50
    • 53149139859 scopus 로고    scopus 로고
    • Genomic alterations and gene expression in primary diffuse large B-cell lymphomas of immune-privileged sites: The importance of apoptosis and immunomodulatory pathways
    • Booman M, Szuhai K, Rosenwald A, et al., Genomic alterations and gene expression in primary diffuse large B-cell lymphomas of immune-privileged sites: the importance of apoptosis and immunomodulatory pathways. J Pathol 2008; 216: 209-217.
    • (2008) J Pathol , vol.216 , pp. 209-217
    • Booman, M.1    Szuhai, K.2    Rosenwald, A.3
  • 51
    • 33749043017 scopus 로고    scopus 로고
    • Primary testicular diffuse large B-cell lymphomas have activated B-cell-like subtype characteristics
    • Booman M, Douwes J, Glas AM, et al., Primary testicular diffuse large B-cell lymphomas have activated B-cell-like subtype characteristics. J Pathol 2006; 210: 163-171.
    • (2006) J Pathol , vol.210 , pp. 163-171
    • Booman, M.1    Douwes, J.2    Glas, A.M.3
  • 52
    • 70449713757 scopus 로고    scopus 로고
    • Inhibition of MALT1 protease activity is selectively toxic for activated B-cell like diffuse large B-cell lymphoma cells
    • Ferch U, Kloo B, Gewies A, et al., Inhibition of MALT1 protease activity is selectively toxic for activated B-cell like diffuse large B-cell lymphoma cells. J Exp Med 2009; 2006: 2313-2320.
    • (2009) J Exp Med , vol.2006 , pp. 2313-2320
    • Ferch, U.1    Kloo, B.2    Gewies, A.3
  • 53
    • 77956578834 scopus 로고    scopus 로고
    • MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: Rationale for treatment of NF-κB-dependent lymphoma
    • Milhollen MA, Traore T, Adams-Duffy J, et al., MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB-dependent lymphoma. Blood 2010; 116: 1515-1523.
    • (2010) Blood , vol.116 , pp. 1515-1523
    • Milhollen, M.A.1    Traore, T.2    Adams-Duffy, J.3
  • 54
    • 35348890981 scopus 로고    scopus 로고
    • Drugging the cancer chaperone HSP90 combinational therapeutic exploitation of oncogene addiction and tumor stress
    • Workman P, Burrows F, Neckers L, et al., Drugging the cancer chaperone HSP90 combinational therapeutic exploitation of oncogene addiction and tumor stress. Ann NY Acad Sci 2007; 1113: 202-216.
    • (2007) Ann NY Acad Sci , vol.1113 , pp. 202-216
    • Workman, P.1    Burrows, F.2    Neckers, L.3
  • 55
    • 9144237554 scopus 로고    scopus 로고
    • Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray
    • Hans CP, Weisenburger DD, Greiner TC, et al., Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray. Blood 2004; 103: 275-282.
    • (2004) Blood , vol.103 , pp. 275-282
    • Hans, C.P.1    Weisenburger, D.D.2    Greiner, T.C.3
  • 56
    • 68549124173 scopus 로고    scopus 로고
    • A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracy
    • Choi WW, Weisenburger DD, Greiner TC, et al., A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracy. Clin Cancer Res 2009; 15: 5494-5502.
    • (2009) Clin Cancer Res , vol.15 , pp. 5494-5502
    • Choi, W.W.1    Weisenburger, D.D.2    Greiner, T.C.3
  • 57
    • 33947538494 scopus 로고    scopus 로고
    • Immunohistochemical prognostic markers in diffuse large B-cell lymphoma: Validation of tissue microarray as a prerequisite for broad clinical applications - A study from the Lunenburg Lymphoma Biomarker Consortium
    • de Jong D, Rosenwald A, Chhanabhai M, et al., Immunohistochemical prognostic markers in diffuse large B-cell lymphoma: validation of tissue microarray as a prerequisite for broad clinical applications-a study from the Lunenburg Lymphoma Biomarker Consortium. J Clin Oncol 2007; 25: 805-812.
    • (2007) J Clin Oncol , vol.25 , pp. 805-812
    • De Jong, D.1    Rosenwald, A.2    Chhanabhai, M.3
  • 58
    • 61449156367 scopus 로고    scopus 로고
    • Immunohistochemical prognostic markers in diffuse large B-cell lymphoma: Validation of tissue microarray as a prerequisite for broad clinical applications (a study from the Lunenburg Lymphoma Biomarker Consortium)
    • de Jong D, Xie W, Rosenwald A, et al., Immunohistochemical prognostic markers in diffuse large B-cell lymphoma: validation of tissue microarray as a prerequisite for broad clinical applications (a study from the Lunenburg Lymphoma Biomarker Consortium). J Clin Pathol 2009; 62: 128-138.
    • (2009) J Clin Pathol , vol.62 , pp. 128-138
    • De Jong, D.1    Xie, W.2    Rosenwald, A.3
  • 59
    • 77954739677 scopus 로고    scopus 로고
    • Comparison of Choi and Hans' algorithms by immunohistochemistry and quantitative reverse transcriptase-PCR-letter
    • Ballabio E, Chi J, Roncador G, et al., Comparison of Choi and Hans' algorithms by immunohistochemistry and quantitative reverse transcriptase-PCR- letter. Clin Cancer Res 2010; 16: 3805-3806.
    • (2010) Clin Cancer Res , vol.16 , pp. 3805-3806
    • Ballabio, E.1    Chi, J.2    Roncador, G.3
  • 60
    • 18244409933 scopus 로고    scopus 로고
    • Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning
    • Shipp MA, Ross KN, Tamayo P, et al., Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning. Nat Med 2002; 8: 68-74.
    • (2002) Nat Med , vol.8 , pp. 68-74
    • Shipp, M.A.1    Ross, K.N.2    Tamayo, P.3
  • 61
    • 20144382754 scopus 로고    scopus 로고
    • Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response
    • Monti S, Savage KJ, Kutok JL, et al., Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response. Blood 2005; 105: 1851-1861.
    • (2005) Blood , vol.105 , pp. 1851-1861
    • Monti, S.1    Savage, K.J.2    Kutok, J.L.3
  • 62
    • 33745198159 scopus 로고    scopus 로고
    • FAS death domain deletions and cellular FADD-like interleukin 1β converting enzyme inhibitory protein (long) overexpression: Alternative mechanisms for deregulating the extrinsic apoptotic pathway in diffuse large B-cell lymphoma subtypes
    • Takahashi H, Feuerhake F, Kutok JL, et al., FAS death domain deletions and cellular FADD-like interleukin 1β converting enzyme inhibitory protein (long) overexpression: alternative mechanisms for deregulating the extrinsic apoptotic pathway in diffuse large B-cell lymphoma subtypes. Clin Cancer Res 2006; 12: 3265-3271.
    • (2006) Clin Cancer Res , vol.12 , pp. 3265-3271
    • Takahashi, H.1    Feuerhake, F.2    Kutok, J.L.3
  • 63
    • 35548935663 scopus 로고    scopus 로고
    • Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma
    • Iqbal J, Greiner TC, Patel K, et al., Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma. Leukemia 2007; 21: 2332-2343.
    • (2007) Leukemia , vol.21 , pp. 2332-2343
    • Iqbal, J.1    Greiner, T.C.2    Patel, K.3
  • 64
    • 33847674920 scopus 로고    scopus 로고
    • Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas
    • Polo JM, Juszczynski P, Monti S, et al., Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas. Proc Natl Acad Sci USA 2007; 104: 3207-3212.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 3207-3212
    • Polo, J.M.1    Juszczynski, P.2    Monti, S.3
  • 65
    • 77951002653 scopus 로고    scopus 로고
    • Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia
    • Friedberg JW, Sharman J, Sweetenham J, et al., Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia. Blood 2010; 115: 2578-2585.
    • (2010) Blood , vol.115 , pp. 2578-2585
    • Friedberg, J.W.1    Sharman, J.2    Sweetenham, J.3
  • 66
    • 41349110211 scopus 로고    scopus 로고
    • SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma
    • Chen L, Monti S, Juszczynski P, et al., SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma. Blood 2008; 111: 2230-2237.
    • (2008) Blood , vol.111 , pp. 2230-2237
    • Chen, L.1    Monti, S.2    Juszczynski, P.3
  • 67
    • 34249075706 scopus 로고    scopus 로고
    • Phase II study of enzastaurin, a protein kinase C β inhibitor, in patients with relapsed or refractory diffuse large B-cell lymphoma
    • Robertson MJ, Kahl BS, Vose JM, et al., Phase II study of enzastaurin, a protein kinase C β inhibitor, in patients with relapsed or refractory diffuse large B-cell lymphoma. J Clin Oncol 2007; 25: 1741-1746.
    • (2007) J Clin Oncol , vol.25 , pp. 1741-1746
    • Robertson, M.J.1    Kahl, B.S.2    Vose, J.M.3
  • 68
    • 51649129260 scopus 로고    scopus 로고
    • Pathway activation patterns in diffuse large B-cell lymphoma
    • Bentink S, Wessendorf S, Schwaenen C, et al., Pathway activation patterns in diffuse large B-cell lymphoma. Leukemia 2008; 22: 1746-1754.
    • (2008) Leukemia , vol.22 , pp. 1746-1754
    • Bentink, S.1    Wessendorf, S.2    Schwaenen, C.3


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