Predicting the contribution of novel POLG mutations to human disease through analysis in yeast model

Mitochondrion

Volumn 11, Issue 1, 2011, Pages 182-190

  Baruffini, Enrico ^a   Horvath, Rita ^b,c   Dallabona, Cristina ^a   Czermin, Birgit ^c   Lamantea, Eleonora ^d   Bindoff, Laurence ^e   Invernizzi, Federica ^d   Ferrero, Iliana ^a   Zeviani, Massimo ^d   Lodi, Tiziana ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c Medical Genetic Center   (Germany)

^d Pierfranco and Luisa Mariani Center for the Study of Children's Mitochondrial Disorders   (Italy)

^e HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

MIP1; Mitochondrial diseases; MtDNA mutability; POLG; ROS scavengers; Yeast model

Indexed keywords

DNA DIRECTED DNA POLYMERASE GAMMA; MITOCHONDRIAL DNA;

ALLELE; ARTICLE; CONTROLLED STUDY; GENE; GENE MUTATION; GENETIC ANALYSIS; NONHUMAN; POINT MUTATION; POLG GENE; PREDICTION; PRIORITY JOURNAL; YEAST;

AMINO ACID SEQUENCE; ANTIOXIDANTS; DNA POLYMERASE I; DNA-DIRECTED DNA POLYMERASE; HUMANS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MOLECULAR SEQUENCE DATA; PHENOTYPE; POINT MUTATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT;

SACCHAROMYCES CEREVISIAE;

EID: 78649984326     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2010.09.007     Document Type: Article

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