Pudendal nerve injury reduces urethral outlet resistance in diabetic rats

American Journal of Physiology - Renal Physiology

Volumn 299, Issue 6, 2010, Pages

  Pan, Hui Q ^a   Lin, Dan L ^a,b   Strauch, Christopher ^c   Butler, Robert S ^a   Monnier, Vincent M ^c   Daneshgari, Firouz ^d   Damaser, Margot S ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Female; Incontinence; Nerve crush; Type I diabetes; Voiding

Indexed keywords

ADVANCED GLYCATION END PRODUCT; BUPRENORPHINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER SPHINCTER; CONTROLLED STUDY; CYSTOMETRY; FEMALE; HISTOPATHOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; MICTURITION DISORDER; MUSCLE CELL; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; RAT; STATISTICAL SIGNIFICANCE; STRESS INCONTINENCE; URETHRA DISEASE; URETHRA OUTLET RESISTANCE; URINE INCONTINENCE;

EID: 78649977635     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00341.2009     Document Type: Article

References (54)

1. Ahn H, Lin DL, Esparza N, Damaser MS. The short-term timecourse of bilateral pudendal nerve injury on leak point pressure in female rats. J Rehab Res Dev 42: 109-114, 2005.
2. Brown JS, Nyberg LM, Kusek JW, Burgio KL, Diokno AC, Foldspang A, Fultz NH, Herzog AR, Hunskaar S, Milsom I, Nygaard I, Subak LL, Thom DH, National Institute of Diabetes and Digestive Kidney Diseases International Research Working Group on Bladder Dysfunction. Proceedings of the National Institute of Diabetes and Digestive and Kidney Diseases International Symposium on Epidemiologic Issues in Urinary Incontinence in Women. Am J Obstet Gynecol 188: S77-S88, 2003.
3. Brown JS, Vittinghoff E, Lin F, Nyberg LM, Kusek JW, Kanaya AM. Prevalence and risk factors for urinary incontinence in women with type 2 diabetes and impaired fasting glucose: findings from the National Health and Nutrition Examination Survey (NHANES) 2001-2002. Diabetes Care 29: 1307-1312, 2006.
4. Cannon TW, Damaser MS. Effects of anesthesia on cystometry and leak point pressure of the female rat. Life Sci 69: 1193-1202, 2001.
5. Cannon TW, Wojcik EM, Ferguson CL, Saraga S, Thomas C, Damaser MS. Effects of vaginal distension on urethral anatomy and function. BJU Int 90: 403-407, 2002.
6. Castro JC, Camargos AF, Goulart EA, Junqueira HS. Sonographic evaluation of bladder volume in diabetic children and adolescents compared with nondiabetic subjects. J Ultrasound Med 23: 1307-1313, 2004.
7. Cellek S, Foxwell NA, Moncada S. Two phases of nitrergic neuropathy in streptozotocin-induced diabetic rats. Diabetes 52: 2353-2362, 2003.
8. Conway DA, Kamo I, Yoshimura N, Chancellor MB, Cannon TW. Comparison of leak point pressure methods in an animal model of stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct 16: 359-363, 2005.
9. Damaser MS, Broxton-King C, Ferguson C, Kim FJ, Kerns JM. Functional and neuroanatomical effects of vaginal distention and pudendal nerve crush in the female rat. J Urol 170: 1027-1031, 2003.
10. Damaser MS, Samplaski MK, Parikh M, Lin DL, Rao S, Kerns JM. Time course of neuroanatomical and functional recovery after bilateral pudendal nerve injury in female rats. Am J Physiol Renal Physiol 293: F1614-F1621, 2007.
11. Damaser MS, Whitbeck C, Chichester P, Levin RM. Effect of vaginal distension on blood flow and hypoxia of urogenital organs of the female rat. J Appl Physiol 98: 1884-1890, 2005.
12. Daneshgari F, Liu G, Imrey P. Time-dependent changes in diabetic cystopathy in rats include compensated and decompensated bladder function. J Urol 176: 380-386, 2006.
13. Daneshgari F, Moore C, Frinjari H, Babineau D. Patient related risk factors for recurrent stress urinary incontinence surgery in women treated at a tertiary care center. J Urol 176: 1493-1499, 2006.
14. Dolan LM, Hosker GL, Mallett VT, Allen RE, Smith ARB. Stress incontinence and pelvic floor neurophysiology 15 years after the first delivery. BJOG 110: 1107-1114, 2003.
15. Eika B, Levin RM, Longhurst PA. Comparison of urinary bladder function in rats with hereditary diabetes insipidus, streptozotocin-induced diabetes mellitus, and nondiabetic osmotic diuresis. J Urol 151: 496-502, 1994.
16. Friedman EA. Advanced glycosylated end products and hyperglycemia in the pathogenesis of diabetic complications. Diabetes Care 22: B65-B71, 1999.
17. Fritel X, Ringa V, Varnoux N, Fauconnier A, Piault S, Breart G. Mode of delivery and severe stress incontinence. A cross-sectional study among 2,625 perimenopausal women. BJOG 112: 1646-1651, 2005.
18. Goh SY, Cooper ME. Clinical review: the role of advanced glycation end products in progression and complications of diabetes. J Clin Endocrinol Metab 93: 1143-1152, 2008.
19. Heidkamp MC, Leong FC, Brubaker L, Russell B. Pudendal denervation affects the structure and function of the striated, urethral sphincter in female rats. Int Urogynecol J Pelvic Floor Dysfunct 9: 88-93, 1998.
20. Hijaz A, Daneshgari F, Sievert KD, Damaser MS. Animal models of female stress urinary incontinence: a review. J Urol 179: 2103-2110, 2008.
21. Hill SR, Fayyad AM, Jones GR. Diabetes mellitus and female lower urinary tract symptoms: a review. Neurourol Urodyn 27: 362-367, 2008.
22. Kamo I, Cannon TW, Conway DA, Torimoto K, Chancellor MB, de Groat WC, Yoshimura N. The role of bladder-to-bladder reflexes in urinary continence mechanisms in rats. Am J Physiol Renal Physiol 287: F434-F441, 2004.
23. Kamo I, Hashimoto T. Involvement of reflex urethral closure mechanisms in urethral resistance under momentary stress condition induced by electrical stimulation of rat abdomen. Am J Physiol Renal Physiol 293: F920-F926, 2007.
24. Kebapci N, Yenilmez A, Efe B, Entok E, Demirustu C. Bladder dysfunction in type 2 diabetic patients. Neurourol Urodyn 26: 814-819, 2007. (Pubitemid 47548248)
25. Kennedy JM, Zochodne DW. Impaired peripheral nerve regeneration in diabetes mellitus. J Peripher Nerv Syst 10: 144-157, 2005.
26. Kerns JM, Damaser MS, Kane JM, Sakamoto K, Benson JT, Shott S, Brubaker L. Effects of pudendal nerve injury in the female rat. Neurourol Urodyn 19: 53-69, 2000.
27. Kim JH, Huang X, Liu G, Moore C, Bena J, Damaser MS, Daneshgari F. Diabetes slows the recovery from urinary incontinence due to simulated childbirth in female rats. Am J Physiol Regul Integr Comp Physiol 293: R950-R955, 2007.
28. Lee WC, Wu HP, Tai TY, Yu HJ, Chiang PH. Investigation of urodynamic characteristics and bladder sensory function in the early stages of diabetic bladder dysfunction in women with type 2 diabetes. J Urol 181: 198-203, 2009.
29. Liu G, Lin YH, Yamada Y, Daneshgari F. External urethral sphincter activity in diabetic rats. Neurourol Urodyn 27: 429-434, 2008. (Pubitemid 351991209)
30. Liu G, Daneshgari F. Alterations in neurogenically mediated contractile responses of urinary bladder in rats with diabetes. Am J Physiol Renal Physiol 288: F1220-F1226, 2005.
31. Liu G, Daneshgari F. Temporal diabetes- and diuresis-induced remodeling of the urinary bladder in the rat. Am J Physiol Regul Integr Comp Physiol 291: R837-R843, 2006.
32. Maggi CA, Conte B. Effect of urethane anesthesia on the micturition reflex in capsaicin-treated rats. J Auton Nerv Syst 30: 247-252, 1990.
33. Maggi CA, Giuliani S, Santicioli P, Meli A. Analysis of factors involved in determining urinary bladder voiding cycle in urethan-anesthetized rats. Am J Physiol Regul Integr Comp Physiol 251: R250-R257, 1986.
34. Maggi CA, Meli A. Suitability of urethane anesthesia for physiopharmacological investigations. Part 3: other systems and conclusions. Experientia 42: 531-537, 1986. (Pubitemid 16042253)
35. Maggi CA, Santicioli P, Meli A. The nonstop transvesical cystometrogram in urethane-anesthetized rats: a simple procedure for quantitative studies on the various phases of urinary bladder voiding cycle. J Pharmacol Methods 15: 157-167, 1986. (Pubitemid 16127076)
36. Matsuura S, Downie JW. Effect of anesthetics on reflex micturition in the chronic cannula-implanted rat. Neurourol Urodyn 19: 87-99, 2000. (Pubitemid 30038856)
37. Pan HQ, Kerns JM, Lin DL, Liu S, Esparza N, Damaser MS. Increased duration of simulated childbirth injuries results in increased time to recovery. Am J Physiol Regul Integr Comp Physiol 292: R1738-R1744, 2007.
38. Pan HQ, Kerns JM, Lin DL, Sypert DF, Steward J, Hoover CRV, Zaszczurynski P, Butler RS, Damaser MS. Dual simulated childbirth injury delays anatomic recovery. Am J Physiol Renal Physiol 296: F277-F283, 2009.
39. Peng CW, Chen JJ, Chang HY, de Groat WC, Cheng CL. External urethral sphincter activity in a rat model of pudendal nerve injury. Neurourol Urodyn 25: 388-396, 2006.
40. Peng CW, Chen JJ, Cheng CL, Grill WM. Improved bladder emptying in urinary retention by electrical stimulation of pudendal afferents. J Neural Eng 5: 144-154, 2008.
41. Samuelsson E, Victor A, Tibblin G. A population study of urinary incontinence and nocturia among women aged 20-59 years. Prevalence, well-being and wish for treatment. Acta Obstet Gynecol Scand 76: 74-80, 1997. (Pubitemid 127733800)
42. Sarma AV, Kanaya AM, Nyberg LM, Kusek JW, Vittinghoff E, Rutledge B, Cleary PA, Gatcomb P, Brown JS, Diabetes control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. Urinary incontinence among women with type 1 diabetes-how common is it? J Urol 181: 1224-1230, 2009.
43. Sell DR, Strauch CM, Shen W, Monnier VM. 2-Aminoadipic acid is a marker of protein carbonyl oxidation in the aging human skin: effects of diabetes, renal failure and sepsis. Biochem J 404: 269-277, 2007. (Pubitemid 46849598)
44. Shoffstall AJ, Zaszczurynski PJ, Butler RS, Damaser MS. Development of a device to standardize leak point pressure experiments in rats. Neurourol Urodyn 27: 553-558, 2008.
45. Steers WD, Mackway AM, Ciambotti J, de Groat WC. Effects of streptozotocin-induced diabetes on bladder function in the rat. J Urol 143: 1032-1036, 1990. (Pubitemid 20156129)
46. Sullivan KA, Feldman EL. New developments in diabetic neuropathy. Curr Opin Neurol 18: 586-590, 2005.
47. Tammela TLJ, Leggett RE, Levin RM, Longhurst PA. Temporal changes in micturition and bladder contractility after sucrose diuresis and streptozotocin-induced diabetes mellitus in rats. J Urol 153: 2014-2021, 1995.
48. Toth C, Martinez J, Zochodne DW. RAGE, diabetes, and the nervous system. Curr Mol Med 7: 766-776, 2007.
49. Turan C, Zorlu CG, Ekin M, Hancerliogullari N, Saracoglu F. Urinary incontinence in women of reproductive age. Gynecol Obstet Invest 41: 132-134, 1996. (Pubitemid 26055566)
50. Wada R, Yagihashi S. Role of advanced glycation end products and their receptors in development of diabetic neuropathy. Annals N Y Acad Sci 1043: 598-604, 2005. (Pubitemid 41123949)
51. Yaksh TL, Durant PAC, Brent CR. Micturition in rats: a chronic model for study of bladder function and effect of anesthetics. Am J Physiol Regul Integr Comp Physiol 251: R1177-R1185, 1986.
52. Yang Z, Dolber PC, Fraser MO. Diabetic urethropathy compounds the effects of diabetic cystopathy. J Urol 178: 2213-2219, 2007.
53. Yang Z, Dolber PC, Fraser MO. Differential vulnerabilities of urethral afferents in diabetes and discovery of a novel urethra-to-urethra reflex. Am J Physiol Renal Physiol 298: F118-F124, 2010.
54. Yoshiyama M, Kakizaki H, de Groat WC. Suppression of the micturition reflex in urethane-anesthitized rats by inreacerebroventricular injection of WAY100635, a 5-HT1A receptor antagonist. Brain Res 980: 281-287, 2003.