Involvement of reflex urethral closure mechanisms in urethral resistance under momentary stress condition induced by electrical stimulation of rat abdomen

American Journal of Physiology - Renal Physiology

Volumn 293, Issue 3, 2007, Pages

  Kamo, Izumi ^a   Hashimoto, Tadatoshi ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Duloxetine; Leak point pressure; Reflex urethral closing responses; Stress urinary incontinence

Indexed keywords

DULOXETINE;

ABDOMINAL PRESSURE; ABDOMINAL WALL MUSCULATURE; ANIMAL EXPERIMENT; ARTICLE; BLADDER PRESSURE; BLADDER SPHINCTER; CONTROLLED STUDY; ELECTROSTIMULATION; FEMALE; HYPOGASTRIC NERVE; MICTURITION REFLEX; NONHUMAN; PELVIC NERVE; PELVIS FLOOR; PRIORITY JOURNAL; PUDENDAL NERVE; RAT; STRESS INCONTINENCE; URETHRA; URINE INCONTINENCE;

EID: 34548602036     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00466.2006     Document Type: Article

References (26)

1. Balmforth J, Cardozo LD. Trends toward less invasive treatment of female stress urinary incontinence. Urology 62: 52-60, 2003.
2. Bremer RE, Barber MD, Coates KW, Dolber PC, Thor KB. Innervation of the levator ani and coccygeus muscles of the female rat. Anat Rec A Discov Mol Cell Evol Biol 275: 1031-1041, 2003.
3. Cannon TW, Sweeney DD, Conway DA, Kamo I, Yoshimura N, Sacks M, Chancellor MB. A tissue-engineered suburethral sling in an animal model of stress urinary incontinence. BJU Int 96: 664-669, 2005.
4. Cannon TW, Yoshimura N, Chancellor MB. Innovations in pharmacotherapy for stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct 14: 367-372, 2003.
5. Chancellor MB, Perkin H, Yoshimura N. Recent advances in the neurophysiology of stress urinary incontinence. Scand J Urol Nephrol 39: 21-24, 2005.
6. Chen KJ, Chen LW, Liao JM, Chen CH, Ho YC, Cheng CL, Lin JJ, Huang PC, Lin TB. Effects of a calcineurin inhibitor, tacrolimus, on glutamate-dependent potentiation in pelvic-urethral reflex in anesthetized rats. Neuroscience 138: 69-76, 2006.
7. Conway DA, Kamo I, Yoshimura N, Chancellor MB, Cannon TW. Comparison of leak point pressure methods in an animal model of stress urinary incontinence. J Urol 169: 1503A, 2003.
8. Damaser MS, Kim FJ, Minetti GM. Methods of testing urethral resistance in the female rat. Adv Exp Med Biol 539: 831-839, 2003.
9. De Groat WC. A neurologic basis for the overactive bladder. Urology 50, Suppl: 36-52; discussion 53-56, 1997.
10. Fraser MO, Chancellor MB. Neural control of the urethra and development of pharmacotherapy for stress urinary incontinence. BJU Int 91: 743-748, 2003.
11. Jankowski RJ, Prantil RL, Chancellor MB, de Groat WC, Huard J, Vorp DA. Biomechanical characterization of the urethral musculature. Am J Physiol Renal Physiol 290: F1127-F1134, 2006.
12. Jankowski RJ, Prantil RL, Fraser MO, Chancellor MB, De Groat WC, Huard J, Vorp DA. Development of an experimental system for the study of urethral biomechanical function. Am J Physiol Renal Physiol 286: F225-F232, 2004.
13. Kaiho Y, Kamo I, Chancellor MB, Arai Y, de Groat WC, Yoshimura N. Role of noradrenergic pathways in sneeze-induced urethral continence reflex in rats. Am J Physiol Renal Physiol 292: F639-F646, 2007.
14. Kamo I, Cannon TW, Conway DA, Torimoto K, Chancellor MB, de Groat WC, Yoshimura N. The role of bladder-to-urethral reflexes in urinary continence mechanisms in rats. Am J Physiol Renal Physiol 287: F434-F441, 2004.
15. Kamo I, Torimoto K, Chancellor MB, de Groat WC, Yoshimura N. Urethral closure mechanisms under sneeze-induced stress condition in rats: a new animal model for evaluation of stress urinary incontinence. Am J Physiol Regul Integr Comp Physiol 285: R356-R365, 2003.
16. Lin SY, Chen GD, Liao JM, Pan SF, Chen MJ, Chen JC, Peng HY, Ho YC, Huang PC, Lin JJ, Lin TB. Estrogen modulates the spinal N-methyl-D-aspartic acid-mediated pelvic nerve-to-urethra reflex plasticity in rats. Endocrinology 147: 2956-2963, 2006.
17. Lin TB. Dynamic pelvic-pudendal reflex plasticity mediated by glutamate in anesthetized rats. Neuropharmacology 44: 163-170, 2003.
18. Manzo J, Vazquez MI, Cruz MR, Hernandez ME, Carrillo P, Pacheco P. Fertility ratio in male rats: effects after denervation of two pelvic floor muscles. Physiol Behav 68: 611-618, 2000.
19. McGuire EJ, Woodside JR. Diagnostic advantages of fluoroscopic monitoring during urodynamic evaluation. J Urol 125: 830-834, 1981.
20. Pacheco P, Martinez-Gomez M, Whipple B, Beyer C, Komisaruk BR. Somato-motor components of the pelvic and pudendal nerves of the female rat. Brain Res 490: 85-94, 1989.
21. Poortmans A, Wyndaele JJ. M. levator ani in the rat: does it really lift the anus? Anat Rec 251: 20-27, 1998.
22. Sarkar PK, Ritch AE. Management of urinary incontinence. J Clin Pharm Ther 25: 251-263, 2000.
23. Schuessler B, Baessler K. Pharmacologic treatment of stress urinary incontinence: expectations for outcome. Urology 62: 31-38, 2003.
24. Sievert KD, Emre Bakircioglu M, Tsai T, Dahms SE, Nunes L, Lue TF. The effect of simulated birth trauma and/or ovariectomy on rodent continence mechanism. Part I: functional and structural change. J Urol 166: 311-317, 2001.
25. Thor KB. Serotonin and norepinephrine involvement in efferent pathways to the urethral rhabdosphincter: implications for treating stress urinary incontinence. Urology 62: 3-9, 2003.
26. Thor KB, Katofiasc MA. Effects of duloxetine, a combined serotonin and norepinephrine reuptake inhibitor, on central neural control of lower urinary tract function in the chloralose-anesthetized female cat. J Pharmacol Exp Ther 274: 1014-1024, 1995.