Dual role of the carboxyl-terminal region of pig liver l-kynurenine 3-monooxygenase: Mitochondrial-targeting signal and enzymatic activity

Journal of Biochemistry

Volumn 148, Issue 6, 2010, Pages 639-650

  Hirai, Kumiko ^a   Kuroyanagi, Hidehito ^b,g   Tatebayashi, Yoshitaka ^a   Hayashi, Yoshitaka ^a   Hirabayashi Takahashi, Kanako ^c   Saito, Kuniaki ^c,h   Haga, Seiich ^d   Uemura, Tomihiko ^e,f   Izumi, Susumu ^f,i  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^c GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d Tokyo Metropolitan College of Technology   (Japan)

^e Tama Psychiatric Hospital   (Japan)

^f TOKYO METROPOLITAN UNIVERSITY   (Japan)

^g TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^h KYOTO UNIVERSITY   (Japan)

ⁱ KANAGAWA UNIVERSITY   (Japan)

Author keywords

Carboxyl terminal truncation; hydrophobic C terminal domain; l kynurenine 3 monooxygenase; mitochondrial tail anchored protein; mitochondrial targeting signal

Indexed keywords

COMPLEMENTARY DNA; KYNURENINE 3 MONOOXYGENASE; MEMBRANE PROTEIN; MUTANT PROTEIN; PLASMID DNA; XANTHURENIC ACID;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; ENZYME ACTIVITY; ENZYME LOCALIZATION; HYDROPHOBICITY; IMMUNOFLUORESCENCE MICROSCOPY; LIVER; LIVER MITOCHONDRION; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; SWINE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BIOCATALYSIS; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; COS CELLS; ENZYME ACTIVATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KYNURENINE; KYNURENINE 3-MONOOXYGENASE; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; NADP; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SEQUENCE DELETION; SWINE;

SUIDAE;

EID: 78649975341     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvq099     Document Type: Article

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