Reducing bounce effects in the Andersen cascade impactor

International Journal of Pharmaceutics

Volumn 301, Issue 1-2, 2005, Pages 25-32

  Dunbar, Craig ^a   Kataya, Abdo ^a   Tiangbe, Tiba ^a  

^a ALKERMES INC   (United States)

Author keywords

Bounce effects; Cascade impaction; Large porous particles

Indexed keywords

GLASS; SOLVENT; WATER;

ANALYTIC METHOD; ARTICLE; DRUG DELIVERY SYSTEM; GEOMETRY; PARTICLE SIZE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; STATISTICS; VACUUM; VELOCITY;

ALGORITHMS; CALIBRATION; DRUG COMPOUNDING; FILTRATION; PARTICLE SIZE; POROSITY; POWDERS; SOLVENTS; WATER;

EID: 23944523863     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2005.04.039     Document Type: Article

References (32)

1. L. Asking, and B. Olsson Calibration at different flow rates of a multistage liquid impinger Aerosol Sci. Technol. 27 1997 39 49
2. E.B. Barr, G.J. Newton, and H.-C. Yeh Nonideal collection characteristics of a cascade impactor with various collection substrates Environ. Sci. Technol. 16 1982 633 635
3. Y.-S. Cheng, and H.-C. Yeh Particle bounce in cascade impactors Environ. Sci. Technol. 13 1979 1392 1396
4. K.M. Cushing, J.D. McCain, and W.B. Smith Experimental determination of sizing parameters and wall losses of five source-test cascade impactors Environ. Sci. Technol. 13 1979 726 731
5. S.P. Duddu, S.A. Sisk, Y.H. Walter, T.E. Tarara, K.R. Trimble, A.R. Clark, M.A. Eldong, R.C. Elton, M. Pickford, P.H. Hirst, S.P. Newman, and J.G. Weers Improved lung delivery from a passive dry powder inhaler using an engineered Pulmosphere Powder Pharm. Res. 19 2002 689 695
6. C.A. Dunbar, and A.J. Hickey Evaluation of probability density functions to estimate particle size distributions of pharmaceutical aerosols J. Aerosol Sci. 31 2000 813 831
7. Dunbar, C.A., Mitchell, J.P., 2005. Analysis of cascade impactor mass distributions. J. Aerosol Med., in press.
8. C.A. Dunbar, G. Scheuch, K. Sommerer, M. DeLong, A. Verma, and R. Batycky In vitro and in vivo dose delivery characteristics of large porous particles for inhalation Int. J. Pharm. 245 2002 179 189
9. T.G. Dzubay, L.E. Hines, and R.K. Stevens Particle bounce errors in cascade impactors Atmos. Environ. 10 1976 229 234
10. D.A. Edwards, J. Hanes, G. Caponetti, J. Hrkach, A. Ben-Jebria, M.L. Eskew, J. Mintzes, D. Deaver, N. Lotan, and R. Langer Large porous particles for pulmonary drug delivery Science 276 1997 1868 1871
11. EP, 1997. Preparations for inhalation: aerodynamic assessment of fine particles. In: European Pharmacopoeia, European Pharmacopoeia Convention, pp. 143-150.
12. N.A. Esmen, and T.C. Lee Distortion of cascade impactor measured size distribution due to bounce and blow-off Am. Ind. Hyg. Assoc. J. 1980 410 419
13. FDA, 1998. Metered dose inhaler (MDI) and dry powder inhaler (DPI) drug products: chemistry, manufacturing and controls documentation - draft guidance for industry.
14. W.C. Hinds, W.-C.V. Liu, and J.R. Froines Particle bounce in a personal cascade impactor: a field evaluation Am. Ind. Hyg. Assoc. J. 46 1985 517 523
15. I.G. Kavouras, and P. Koutrakis Use of polyurethane foam as the impaction substrate/collection medium in conventional inertial impactors Aerosol Sci. Technol. 34 2001 46 56
16. D. Lawson Impaction surface coatings intercomparison and measurements with cascade impactors Atmos. Environ. 14 1980 195 199
17. G.R. Markowski Reducing blowoff in cascade impactor measurements Aerosol Sci. Technol. 1984 431 439
18. V.A. Marple, and K.L. Rubow Theory and design guidelines J. Lodge T. Chan Cascade Impactor Sampling and Design 1986 AIHA Akron, OH 79 101
19. K.R. May The cascade impactor: an instrument for sampling course aerosols J. Sci. Instrum. 22 1945 187 195
20. J.P. Mitchell, P.A. Costa, and S. Waters An assessment of an Andersen mark-II cascade impactor J. Aerosol Sci. 19 1988 213 221
21. J.P. Mitchell, and N.M. Nagel Cascade impactors for the size characterization of aerosols from medical inhalers: their uses and limitations J. Aerosol Med. 16 2004 341 377
22. S.C. Nichols, and M.J. Smurthwaite The Andersen cascade impactor: calibration data, operation at various flow rates and modified for use with DPIs at various flow rates R. Dalby P. Byron S. Farr RDD VI 1998 Interpharm Press Buffalo Grove, IL 393 396
23. F. Podczeck Optimization of the operation conditions of an Andersen-cascade impactor and the relationship to centrifugal adhesion measurements to aid the development of dry powder inhalations Int. J. Pharm. 149 1997 51 61
24. A.K. Roa, and K.T. Whitby Non-ideal collection characteristics of inertial impactors-I. Single stage impactors and solid particles J. Aerosol Sci. 9 1978 77 86
25. A.K. Roa, and K.T. Whitby Non-ideal collection characteristics of inertial impactors-II. Cascade impactors J. Aerosol Sci. 9 1978 87 100
26. P.D. Swanson, F.J. Muzzio, A. Annapragada, and A. Adjei Numerical analysis of motion and deposition of particles in cascade impactors Int. J. Pharm. 142 1996 33 51
27. C.-J. Tsai, and Y.-H. Cheng Solid particle collection characteristics on impaction surfaces of different designs Aerosol Sci. Technol. 23 1995 96 106
28. J.R. Turner, and S.V. Hering Greased and oiled substrates as bounce-free impaction surfaces J. Aerosol Sci. 18 1987 215 224
29. USP<601>. Aerosols, metered-dose inhalers and dry powder inhalers <601>. In: US Pharmacopoeia, US Pharmacopeial Convention, Rockville, MD, pp. 4933-4949.
30. N.P. Vaughan The Andersen impactor: calibration, wall losses and numerical simulation J. Aerosol Sci. 20 1989 67 90
31. P. Winkler Relative humidity and the adhesion of atmospheric particles to the plates of impactors Aerosol Sci. 5 1974 235 240
32. A.D. Zimon Adhesion of Dust and Powder 1982 Consultants Bureau New York