Impact of counterion on the chemical stability of crystalline salts of procaine

Journal of Pharmaceutical Sciences

Volumn 99, Issue 9, 2010, Pages 3719-3730

  Guerrieri, Peter ^a   Jarring, Kjell ^b   Taylor, Lynne S ^a  

^a PURDUE UNIVERSITY   (United States)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Chemical stability; Counterion; Hydrolysis; Hygroscopicity; Isothermal calorimetry; Microenvironment; Salts; Solid state; Surface chemistry

Indexed keywords

COUNTERION; PROCAINE;

ADSORPTION; ARTICLE; CRYSTAL STRUCTURE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; DRUG SYNTHESIS; ENTHALPY; MOISTURE; PH; SOLID STATE; WETTABILITY;

EID: 77956367297     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22009     Document Type: Article

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