Efficiency of neural drive during exercise in patients with COPD and healthy subjects

Chest

Volumn 138, Issue 6, 2010, Pages 1309-1315

  Qin, Yin Yin ^a   Steier, Joerg ^b   Jolley, Caroline ^b   Moxham, John ^b   Zhong, Nan Shan ^a   Luo, Yuan Ming ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAPHRAGM; ELECTRODE; ELECTROMYOGRAM; ESOPHAGUS; EXERCISE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG MINUTE VOLUME; MALE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RESPIRATORY DRIVE; TREADMILL EXERCISE; WORK;

EID: 78649889000     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.09-2824     Document Type: Article

References (35)

1. Calverley PM. Dynamic hyperinflation: is it worth measuring? Proc Am Thorac Soc. 2006;3(3):239-44.
2. Polkey MI, Kyroussis D, Keilty SE, et al. Exhaustive treadmill exercise does not reduce twitch transdiaphragmatic pressure in patients with COPD. Am J Respir Crit Care Med. 1995;152(3):959-64.
3. Mador MJ, Kufel TJ, Pineda LA, Sharma GK. Diaphragmatic fatigue and high-intensity exercise in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2000;161(1):118-23.
4. Luo YM, Moxham J. Measurement of neural respiratory drive in patients with COPD. Respir Physiol Neurobiol. 2005;146(2-3):165-74.
5. Sinderby C, Spahija J, Beck J, et al. Diaphragm activation during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2001;163(7):1637-641.
6. Polkey MI, Hamnegård CH, Hughes PD, Rafferty GF, Green M, Moxham J. Influence of acute lung volume change on contractile properties of human diaphragm. J Appl Physiol. 1998;85(4):1322-328.
7. Luo YM, Wu HD, Tang J, et al. Neural respiratory drive during apnoeic events in obstructive sleep apnoea. Eur Respir J. 2008;31(3):650-57.
8. Jolley CJ, Luo YM, Steier J, et al. Neural respiratory drive in healthy subjects and in COPD. Eur Respir J. 2009;33(2):289-97.
9. Ninane V, Rypens F, Yernault JC, De Troyer A. Abdominal muscle use during breathing in patients with chronic airflow obstruction. Am Rev Respir Dis. 1992;146(1):16-1.
10. De Troyer A, Leeper JB, McKenzie DK, Gandevia SC. Neural drive to the diaphragm in patients with severe COPD. Am J Respir Crit Care Med. 1997;155(4):1335-340.
11. Luo YM, Hart N, Mustfa N, Lyall RA, Polkey MI, Moxham J. Effect of diaphragm fatigue on neural respiratory drive. J Appl Physiol. 2001;90(5):1691-699.
12. Luo YM, Lyall RA, Harris ML, et al. Effect of lung volume on the oesophageal diaphragm EMG assessed by magnetic phrenic nerve stimulation. Eur Respir J. 2000;15(6):1033-038.
13. Luo YM, Tang J, Jolley C, et al. Distinguishing obstructive from central sleep apnea events: diaphragm electromyogram and esophageal pressure compared. Chest. 2009;135(5):1133-141.
14. Hussain SN, Pardy RL, Dempsey JA. Mechanical impedance as determinant of inspiratory neural drive during exercise in humans. J Appl Physiol. 1985;59(2):365-75.
15. Gorini M, Spinelli A, Ginanni R, et al. Neural respiratory drive and neuromuscular coupling during CO2 rebreathing in patients with chronic interstitial lung disease. Chest. 1989;96(4):824-30.
16. Singh B, Eastwood PR, Finucane KE. Volume displaced by diaphragm motion in emphysema. J Appl Physiol. 2001;91(5):1913-923.
17. Steier J, Jolley CJ, Seymour J, Roughton M, Polkey MI, Moxham J. Neural respiratory drive in obesity. Thorax. 2009;64(8):719-25.
18. Beck J, Gottfried SB, Navalesi P, et al. Electrical activity of the diaphragm during pressure support ventilation in acute respiratory failure. Am J Respir Crit Care Med. 2001;164(3):419-24.
19. American Thoracic Society/European Respiratory Society. ATS/ERS Statement on respiratory muscle testing. Am J Respir Crit Care Med. 2002;166(4):518-24.
20. Luo YM, Lyall RA, Lou Harris M, Rafferty GF, Polkey MI, Moxham J. Quantification of the esophageal diaphragm electromyogram with magnetic phrenic nerve stimulation. Am J Respir Crit Care Med. 1999;160(5 pt 1):1629-634.
21. Beck J, Sinderby C, Lindström L, Grassino A. Effects of lung volume on diaphragm EMG signal strength during voluntary contractions. J Appl Physiol. 1998;85(3):1123-134.
22. Beck J, Sinderby C, Lindström L, Grassino A. Crural diaphragm activation during dynamic contractions at various inspiratory flow rates. J Appl Physiol. 1998;85(2):451-58.
23. Luo YM, Moxham J, Polkey MI. Diaphragm electromyography using an oesophageal catheter: current concepts. Clin Sci (Lond). 2008;115(8):233-44.
24. Luo YM, Qiu ZH, Wu HD, et al. Neural drive during continuous positive airway pressure (CPAP) and pressure relief CPAP. Sleep Med. 2009;10(7):731-38.
25. Dayer MJ, Hopkinson NS, Ross ET, et al. Does symptomlimited cycle exercise cause low frequency diaphragm fatigue in patients with heart failure? Eur J Heart Fail. 2006;8(1):68-3.
26. Johnson BD, Babcock MA, Suman OE, Dempsey JA. Exercise-induced diaphragmatic fatigue in healthy humans. J Physiol. 1993;460:385-05.
27. Dayer MJ, Jonville S, Chatwin M, et al. Exercise-induced depression of the diaphragm motor evoked potential is not affected by non-invasive ventilation. Respir Physiol Neurobiol. 2007;155(3):243-54.
28. Laghi F, Cattapan SE, Jubran A, et al. Is weaning failure caused by low-frequency fatigue of the diaphragm? Am J Respir Crit Care Med. 2003;167(2):120-27.
29. Ferguson GT. Respiratory failure due to altered central drive during inspiratory loading in rabbits. Respir Physiol. 1995;99(1):75-7.
30. Sassoon CS, Gruer SE, Sieck GC. Temporal relationships of ventilatory failure, pump failure, and diaphragm fatigue. J Appl Physiol. 1996;81(1):238-45.
31. Luo YM, Li RF, Jolley C, et al. Neural respiratory drive in patients with COPD during exercise tests. Respiration. In press.
32. O'Donnell DE, Revill SM, Webb KA. Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2001;164(5):770-77.
33. O'Donnell DE, Webb KA. Exertional breathlessness in patients with chronic airflow limitation. The role of lung hyperinflation. Am Rev Respir Dis. 1993;148(5):1351-357.
34. O'Donnell DE, Hong HH, Webb KA. Respiratory sensation during chest wall restriction and dead space loading in exercising men. J Appl Physiol. 2000;88(5):1859-869.
35. Killian KJ, Summers E, Jones NL, Campbell EJ. Dyspnea and leg effort during incremental cycle ergometry. Am Rev Respir Dis. 1992;145(6):1339-345.