Diaphragmatic fatigue and high-intensity exercise in patients with chronic obstructive pulmonary disease

American Journal of Respiratory and Critical Care Medicine

Volumn 161, Issue 1, 2000, Pages 118-123

  Mador, M Jeffery ^a,b   Kufel, Thomas J ^a   Pineda, Lilibeth A ^a   Sharma, Gyanendra K ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b VA WESTERN NEW YORK HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BICYCLE ERGOMETRY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; DIAPHRAGM MUSCLE; EXERCISE TOLERANCE; FORCED EXPIRATORY VOLUME; HUMAN; MAGNETIC STIMULATION; MALE; MUSCLE CONTRACTILITY; MUSCLE FATIGUE; MUSCLE TWITCH; OXYGEN CONSUMPTION; PHRENIC NERVE; PRIORITY JOURNAL; WORK CAPACITY; WORKLOAD;

EID: 0033983246     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.161.1.9903010     Document Type: Article

References (35)

1. 1. Belman, M. J. 1992. Factors limiting exercise performance in lung disease: ventilatory insufficiency. Chest 101:253S-254S.
2. 2. Younes, M. 1990. Determinants of thoracic excursions during exercise. In B. J. Whipp and K. Wasserman, editors. Pulmonary Physiology and Pathophysiology of Exercise: Lung Biology in Health and Disease. Marcel Dekker, New York. 1-65.
3. 3. Bye, P. T. P., S. A. Esau, R. D. Levy, R. J. Shiner, P. T. Macklem, J. G. Martin, and R. L. Pardy. 1985. Ventilatory muscle function during exercise in air and oxygen in patients with chronic air-flow limitation. Am. Rev. Respir. Dis. 132:236-240.
4. 4. Kyroussis, D., M. I. Polkey, S. E. J. Keilty, G. H. Mills, C. H. Hamnegard, J. Moxham, and M. Green. 1996. Exhaustive exercise slows inspiratory muscle relaxation rate in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 153:789-793.
5. 5. Polkey, M. I., D. Kyroussis, S. E. J. Keilty, C. H. Hamnegard, G. H. Mills, M. Green, and J. Moxham. 1995. Exhaustive treadmill exercise does not reduce twitch transdiaphragmatic pressure in patients with COPD. Am. J. Respir. Crit. Care Med. 152:959-964.
6. 6. Respiratory Muscle Fatigue Workshop Group. 1990. NHLBI workshop summary: respiratory muscle fatigue. Am. Rev. Respir. Dis. 142:474-480.
7. 7. Laghi, F., N. D'Alfonso, and M. J. Tobin. 1995. Pattern of recovery from diaphragmatic fatigue over 24 hours. J. Appl. Physiol. 79:539-546.
8. 8. Mador, M. J., A. Rodis, and J. Diaz. 1996. Diaphragmatic fatigue following voluntary hyperpnea. Am. J. Respir. Crit. Care Med. 154:63-67.
9. 9. Mador, M. J., and T. Wendel. 1996. Can hyperoxia reduce diaphragmatic fatigue following intense cycle exercise? (abstract). Am. J. Respir. Crit. Care Med. 153:A787.
10. 10. American Thoracic Society. 1995. Standardization of spirometry: 1994 update. Am. J. Respir. Crit. Care Med. 152:1107-1136.
11. 11. Crapo, R. O., A. H. Morris, and R. M. Gardner. 1981. Reference spirometric values using techniques and equipment that meet ATS recommendations. Am. Rev. Respir. Dis. 123:659-664.
12. 12. Crapo, R. O., and A. H. Morris. 1981. Standardized single breath normal values for carbon monoxide diffusing capacity. Am. Rev. Respir. Dis. 123:185-189.
13. 13. Crapo, R. O., A. H. Morris, P. D. Clayton, and C. R. Nixon. 1982. Lung volumes in healthy nonsmoking adults. Bull. Eur. Physiopathol. Respir. 18:419-425.
14. 14. Kory, R. C., R. Callahan, H. G. Borsen, and J. C. Syner. 1961. The Veterans Administration-Army cooperative study of pulmonary function: I. Clinical spirometry in normal men. Am. J. Med. 30:243-258.
15. 15. McElvaney, G., S. Blackie, N. J. Morrison, P. G. Wilcox, M. S. Fairbarn, and R. L. Pardy. 1989. Maximal static respiratory pressures in the normal elderly. Am. Rev. Respir. Dis. 139:277-281.
16. 16. Similowski, T., B. Fleury, S. Launois, H. P. Cathala, P. Bouche, and J. P. Derenne. 1989. Cervical magnetic stimulation: a new painless method for bilateral phrenic nerve stimulation in conscious humans. J. Appl. Physiol. 67:1311-1318.
17. 17. Mador, M. J., A. Rodis, U. J. Magalang, and K. Ameen. 1996. Comparison of cervical magnetic and transcutaneous phrenic nerve stimulation before and after threshold loading. Am. J. Respir. Crit. Care Med. 154: 448-453.
18. 18. Mador, M. J., U. J. Magalang, A. Rodis, and T. J. Kufel. 1993. Diaphragmatic fatigue after exercise in healthy human subjects. Am. Rev. Respir. Dis. 148:1571-1575.
19. 19. Mador, M. J., and M. Dahuja. 1996. Mechanisms for diaphragmatic fatigue following high intensity leg exercise. Am. J. Respir. Crit. Care Med. 154:1484-1489.
20. 20. Mador, M. J., T. Wendel, and T. J. Kufel. 1997. Effect of acute hypercapnia on diaphragmatic and limb muscle contractility. Am. J. Respir. Crit. Care Med. 155:1590-1595.
21. 21. Sokal, R. R., and F. J. Rohlf. 1981. Biometry, 2nd ed. W. H. Freeman and Company, New York.
22. 22. Polkey, M. I., D. Kyroussis, C. H. Hamnegard, G. H. Mills, P. D. Hughes, M. Green, and J. Moxham. 1997. Diaphragm performance during maximal voluntary ventilation in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 155:642-648.
23. 23. Pineda, L. A., T. J. Kufel, and M. J. Mador. 1999. Does exercise induced diaphragmatic fatigue occur in healthy elderly subjects? (abstract). Am. J. Respir. Crit. Care Med. 159:A585.
24. 24. Hamnegard, C. H., S. Wragg, D. Kyroussis, G. H. Mills, M. I. Polkey, J. Moran, J. Road, B. Bake, M. Green, and J. Moxham. 1996. Diaphragm fatigue following maximal ventilation in man. Eur. Respir. J. 9:241-247.
25. 25. Laghi, F., M. J. Harrison, and M. J. Tobin. 1996. Comparison of magnetic and electrical phrenic nerve stimulation in assessment of diaphragmatic contractility. J. Appl. Physiol. 80:1731-1742.
26. 26. Smith, J. F., and F. Bellemare. 1987. Effect of lung volumes on in vivo contraction characteristics of human diaphragm. J. Appl. Physiol. 62: 1893-1900.
27. 27. Dodd, D., T. Brancatisano, and L. Engel. 1984. Chest wall mechanics during exercise in patients with severe chronic airflow obstruction. Am. Rev. Respir. Dis. 129:33-38.
28. 28. Mador, M. J., U. J. Magalang, and T. J. Kufel. 1994. Twitch potentiation following voluntary diaphragmatic contraction. Am. J. Respir. Crit. Care Med. 149:739-743.
29. 29. Bernard, S., P. LeBlanc, F. Whittom, G. Carrier, J. Jobin, R. Belleau, and F. Maltais. 1998. Peripheral muscle weakness in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 158:629-634.
30. 30. Similowski, T., C. Straus, V. Attali, A. Duguet, and J.-P. Derenne. 1998. Cervical magnetic stimulation as a method to discriminate between diaphragm and ribcage muscle fatigue. J. Appl. Physiol. 84:1692-1700.
31. 31. Yan, S., D. Kaminski, and P. Sliwinski. 1997. Inspiratory muscle mechanics of patients with chronic obstructive pulmonary disease during incremental exercise. Am. J. Respir. Crit. Care Med. 156:807-813.
32. 32. Levine, S., L. Kaiser, J. Leferovich, and B. Tikunov. 1997. Cellular adaptations in the diaphragm in chronic obstructive pulmonary disease. N. Engl. J. Med. 337:1799-1806.
33. 33. Mercadier, J. J., K. Schwartz, S. Schiaffino, C. Wisnewsky, S. Ausoni, M. Heimburger, R. Marrash, R. Pariente, and M. Aubier. 1998. Myosin heavy chain gene expression changes in the diaphragm of patients with chronic lung hyperinflation. Am. J. Physiol. 274:L527-L534.
34. 34. Orozco-Levi, M., J. Gea, J. L. Lloreta, M. Felez, J. Minguella, S. Serrano, and J. M. Broquetas. 1999. Subcellular adaptation of the human diaphragm in chronic obstructive pulmonary disease. Eur. Respir. J. 13:371-378.
35. 35. Polkey, M. I., D. Kyroussis, C.-H. Hamnegard, G. H. Mills, P. D. Hughes, M. Green, and J. Moxham. 1997. Diaphragm performance during maximal voluntary ventilation in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med 155:642-648.