Expression and significance of fgl2 prothrombinase in cardiac microvascular endothelial cells of rats with type 2 diabetes

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 30, Issue 5, 2010, Pages 575-581

  Ding, Yanping ^a   Liu, Kun ^a   Wang, Yan ^a   Su, Guanhua ^a   Deng, Heping ^a   Zeng, Qiutang ^a   Liao, Yuhua ^a   Wang, Zhaohui ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

cardiac function; fibrinogen like protein 2; ischemic heart disease; microangiopathy; tumor necrosis factor ; type 2 diabetes

Indexed keywords

FIBRINOGEN; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; CORONARY BLOOD VESSEL; ENDOTHELIUM CELL; ETHNOLOGY; EXPERIMENTAL DIABETES MELLITUS; GENETICS; HEART MUSCLE ISCHEMIA; MALE; METABOLISM; MICROVASCULATURE; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOLOGY; RAT; SPRAGUE DAWLEY RAT; THROMBOSIS;

ANIMALS; CORONARY VESSELS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; ENDOTHELIAL CELLS; FIBRINOGEN; MALE; MICROVESSELS; MYOCARDIAL ISCHEMIA; RATS; RATS, SPRAGUE-DAWLEY; THROMBOPLASTIN; THROMBOSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78649868501     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-010-0545-y     Document Type: Article

References (27)

1. J.A. Beckman M.A. Greager P. Libby 2002 Diabetes and atherosclerosis: Epidemiology, pathophysiology, and management JAMA 287 19 2570 2581 1:CAS:528:DC%2BD38Xjs1GltLc%3D 10.1001/jama.287.19.2570 12020339
2. R. Yarom H. Zirkin G. Stammler, et al. 1992 Human coronary microvessels in diabetes and ischaemia. Morphometric study of autopsy material J Pathol 166 3 265 270 1:STN:280:DyaK38zovFSrtA%3D%3D 10.1002/path.1711660308 1517882
3. H.P. Kohler P.J. Grant 2000 Plasminogen-activator inhibitor type 1 and coronary artery disease N Engl J Med 342 24 1792 1801 1:CAS:528: DC%2BD3cXksVequ7Y%3D 10.1056/NEJM200006153422419 10853003
4. M.E. Carr 2001 Diabetes mellitus: a hypercoagulable state J Diabetes Complications 15 1 44 54 1:STN:280:DC%2BD3M7mtFaruw%3D%3D 10.1016/S1056-8727(00) 00132-X 11259926 (Pubitemid 32203891)
5. D. Boeri M. Maiello M. Lorenzi 2001 Increased prevalence of microthromboses in retinal capillaries of diabetic individuals Diabetes 50 6 1432 1439 1:CAS:528:DC%2BD3MXkvFSgtr0%3D 10.2337/diabetes.50.6.1432 11375345
6. G.A. Levy M. Liu J. Ding, et al. 2000 Molecular and functional analysis of the human prothrombinase gene (HFGL2) and its role in viral hepatitis Am J Pathol 156 4 1217 1225 1:CAS:528:DC%2BD3cXjtV2isbs%3D 10751347
7. C.W. Chan M.W. Chan M. Liu, et al. 2002 Kinetic analysis of a unique direct prothrombinase, fgl2, and identification of a serine residue critical for the prothrombinase activity J Immunol 168 10 5170 5177 1:CAS:528: DC%2BD38XjslSjtLw%3D 11994472
8. J.W. Ding Q. Ning M.F. Liu, et al. 1997 Fulminant hepatic failure in murine hepatitis virus strain 3 infection: Tissue-specific expression of a novel fgl2 prothrombinase J Virol 71 12 9223 9230 1:CAS:528:DyaK2sXnsVClurs%3D 9371581
9. P.A. Marsden Q. Ning L.S. Fung, et al. 2003 The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis J Clin Invest 112 1 58 66 1:CAS:528:DC%2BD3sXlt1Krt7s%3D 12840059
10. A. Ghanekar M. Mendicino H. Liu, et al. 2004 Endothelial induction of fgl2 contributes to thrombosis during acute vascular xenograft rejection J Immunol 172 9 5693 5701 1:CAS:528:DC%2BD2cXjt1Cktbc%3D 15100314
11. M. Mendicino M. Liu A. Ghanekar, et al. 2005 Targeted deletion of Fgl-2/fibroleukin in the donor modulates immunologic response and acute vascular rejection in cardiac xenografts Circulation 112 2 248 256 1:CAS:528: DC%2BD2MXlvVSnsL0%3D 10.1161/CIRCULATIONAHA.105.534271 15998670 (Pubitemid 40982308)
12. D.A. Clark J.W. Ding G. Chaouat, et al. 1999 The emerging role of immunoregulation of fibrinogen-related procoagulant Fgl2 in the success or spontaneous abortion of early pregnancy in mice and humans Am J Reprod Immunol 42 1 37 43 1:STN:280:DyaK1MzlvVeqtA%3D%3D 10429765
13. M.K. Knackstedt A.C. Zenclussen K. Hertwig, et al. 2003 Th1 cytokines and the prothrombinase fgl2 in stress-tri ggered and inflammatory abortion Am J Reprod Immunol 49 4 210 220 1:STN:280:DC%2BD3szit1Onsw%3D%3D 10.1034/j.1600-0897.2003.01192.x 12852495 (Pubitemid 36612064)
14. D.A. Clark K. Foerster L. Fung, et al. 2004 The fgl2 prothrombinase/ fibroleukin gene is required for lipopolysaccharide-triggered abortions and for normal mouse reproduction Mol Hum Reprod 10 2 99 108 1:CAS:528: DC%2BD2cXms1amsQ%3D%3D 10.1093/molehr/gah013 14742694 (Pubitemid 38196511)
15. J. Luo J. Quan J. Tsai, et al. 1998 Nongenetic mouse models of non-insulin-dependent diabetes mellitus Metabolism 47 6 663 668 1:CAS:528:DyaK1cXjslymtLk%3D 10.1016/S0026-0495(98)90027-0 9627363 (Pubitemid 28265168)
16. R.F. Doolittle 1983 The structure and evolution of vertebrate fibrinogen Ann N Y Acad Sci 408 13 27 1:CAS:528:DyaL3sXkvVeqtrY%3D 10.1111/j.1749-6632. 1983.tb23231.x 6575681
17. G.A. Levy P. Marsden R. Zhong, et al. 1998 Strategies to prevent thrombosis in xenotransplants Transplant Proc 30 5 2458 2460 1:STN:280:DyaK1czptV2kug%3D%3D 10.1016/S0041-1345(98)00685-X 9723536 (Pubitemid 28402916)
18. Q. Ning D. Brown J. Parodo, et al. 1998 Ribavirin inhibits viral-induced macrophage production of TNF-α, IL-1, the procoagulant fgl2 prothrombinase and preserves Th1 cytokine production but inhibits Th2 cytokine response J Immunol 160 7 3487 3493 1:CAS:528:DyaK1cXitFWrt7c%3D 9531310
19. D.A. Clark G. Chaouat P.C. Arck, et al. 1998 Cytokine-dependent abortion in CBA × DBA/2 mice is mediated by the procoagulant fgl2 prothrombinase [correction of prothombinase] J Immunol 160 2 545 549 1:CAS:528: DyaK1cXls1ersQ%3D%3D 9551885
20. D.A. Clark J.W. Ding G. Yu, et al. 2001 Fgl2 prothrombinase expression in mouse trophoblast and decidua triggers abortion but may be countered by OX-2 Mol Hum Reprod 7 2 185 194 1:CAS:528:DC%2BD3MXhsFahtr0%3D 10.1093/molehr/7.2.185 11160845
21. M. Liu M. Mendicino Q. Ning, et al. 2006 Cytokine-induced hepatic apoptosis is dependent on FGL2/fibroleukin: the role of Sp1/Sp3 and STAT1/PU.1 composite cis elements J Immunol 176 11 7028 7038 1:CAS:528:DC%2BD28XkslWgsrk%3D 16709865
22. W. Aldhahi O. Hamdy 2003 Adipokines, inflammation, and the endothelium in diabetes Curr Diab Rep 3 4 293 298 10.1007/s11892-003-0020-2 12866991
23. D.J. Rader 2000 Inflammatory markers of coronary risk N Eng J Med 343 16 1179 1182 1:STN:280:DC%2BD3cvpslChsQ%3D%3D 10.1056/NEJM200010193431609
24. S. Yagihashi R. Wada S. Yamagishi 2002 Diabetic microangiopathy: pathology and current understanding of its pathogenesis Verh Dtsch Ges Pathol 86 91 100 1:CAS:528:DC%2BD3sXisVWgurg%3D 12647356
25. S. Rubler J. Dlugash Y.Z. Yuceoglu, et al. 1972 New type of cardiomyopathy associated with diabetic glomerulosclerosis Am J Cardiol 30 6 595 602 1:STN:280:DyaE3s%2FjtFeksA%3D%3D 10.1016/0002-9149(72)90595-4 4263660
26. R.I. Hamby S. Zoneraich L. Sherman 1974 Diabetic cardiomyopathy JAMA 229 13 1749 1754 1:STN:280:DyaE2M%2FgvVOgtg%3D%3D 10.1001/jama.229.13.1749 4278055
27. N.S. Dhalla X. Liu V. Panagia, et al. 1998 Subcellular remodeling and heart dysfunction in chronic diabetes Cardiovasc Res 40 2 239 247 1:CAS:528:DyaK1cXnsFKksro%3D 10.1016/S0008-6363(98)00186-2 9893715 (Pubitemid 28506032)