SMOC2 gene variant and the risk of vitiligo in Jordanian Arabs

European Journal of Dermatology

Volumn 20, Issue 6, 2010, Pages 701-704

  Alkhateeb, Asem ^a   Marzouka, Nour Al Dain ^a   Qarqaz, Firas ^a  

^a JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Jordan)

Author keywords

Genetics; SMOC2; Vitiligo

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; GENE; GENE FREQUENCY; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; JORDAN; MALE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SECRETED MODULAR CALCIUM BINDING GENE; VITILIGO;

ADULT; ALLELES; ARABS; CALCIUM-BINDING PROTEINS; CASE-CONTROL STUDIES; FEMALE; GENETIC VARIATION; GENOTYPE; HUMANS; JORDAN; MALE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RISK FACTORS; ROMANIA; VITILIGO;

EID: 78649865989     PISSN: 11671122     EISSN: 19524013     Source Type: Journal    
DOI: 10.1684/ejd.2010.1095     Document Type: Article

References (34)

1. Boissy RE, Spritz RA. Frontiers and controversies in the pathobiology of vitiligo: separating the wheat from the chaff. Exp Dermatol 2009; 18: 583-5.
2. Howitz J, Brodthagen H, Schwartz M, et al. Prevalence of vitiligo. Epidemiological survey on the Isle of Bornholm, Denmark. Arch Dermatol 1977; 113: 47-52.
3. Sun X, Xu A, Wei X, et al. Genetic epidemiology of vitiligo: a study of 815 probands and their families from south China. Int J Dermatol 2006; 45: 1176-81. (Pubitemid 44560366)
4. Alkhateeb A, Fain PR, Thody A, et al. Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families. Pigment Cell Res 2003; 16: 208-14. (Pubitemid 36597056)
5. Laberge G, Mailloux CM, Gowan K, et al. Early disease onset and increased risk of other autoimmune diseases in familial generalized vitiligo. Pigment Cell Res 2005; 18: 300-5. (Pubitemid 41032889)
6. Blomhoff A, Kemp EH, Gawkrodger DJ, et al. CTLA4 polymorphisms are associated with vitiligo, in patients with concomitant autoimmune diseases. Pigment Cell Res 2005; 18: 55-8. (Pubitemid 40170606)
7. Birlea SA, Laberge GS, Procopciuc LM, et al. CTLA4 and generalized vitiligo: two genetic association studies and a meta-analysis of published data. Pigment Cell Melanoma Res 2009; 22: 230-4.
8. Retornaz G, Betuel H, Ortonne JP, et al. HL-A antigens and vitiligo. Br J Dermatol 1976; 95: 173-5.
9. Le Poole IC, Luiten RM. Autoimmune etiology of generalized vitiligo. Curr Dir Autoimmun 2008; 10: 227-43.
10. Jin Y, Mailloux CM, Gowan K, et al. NALP1 in vitiligo-associated multiple autoimmune disease. N Engl J Med 2007; 356: 1216-25. (Pubitemid 46465597)
11. Jin Y, Birlea SA, Fain PR, et al. Genetic variations in NALP1 are associated with generalized vitiligo in a Romanian population. J Invest Dermatol 2007; 127: 2558-62. (Pubitemid 47585070)
12. Canton I, Askhatar S, Gavalas NG, et al. A single-nucleotide polymorphism in the gene encoding lymphoid protein tyrosinase phosphatase PTPN22 confers susceptibility to generalized vitiligo. Genes Immun 2005; 6: 584-7. (Pubitemid 41637665)
13. Laddha NC, Dwivedi M, Shajil EM, et al. Association of PTPN22 1858C/T polymorphism with vitiligo susceptibility in Gujarat population. J Dermatol Sci 2007; 49: 260-2.
14. LaBerge GS, Bennett DC, Fain PR, et al. PTPN22 is genetically associated with risk of generalized vitiligo, but CTLA4 is not. J Invest Dermatol 2008; 128: 1757-62.
15. LaBerge GS, Birlea SA, Fain PR, et al. The PTPN22-1858C>T (R620W) functional polymorphism is associated with generalized vitiligo in the Romanian population. Pigment Cell Melanoma Res 2008; 21: 206-8.
16. Spritz RA. The genetics of generalized vitiligo. Curr Dir Autoimmun 2008; 10: 244-57.
17. Birlea SA, Gowan K, Fain PR, Spritz RA. Genome-wide association study of Generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8. J Invest Dermatol 2010; 130: 798-803.
18. Lou DF, Bui MM, Muir A, et al. Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27. Am J Hum Genet 1995; 57: 911-9.
19. Davies JL, Cucca F, Goy JV, et al. Saturation multipoint linkage mapping of chromosome6q in type 1 diabetes. Hum Mol Genet 1996; 5: 1071-4. (Pubitemid 26232295)
20. Owerbach D. Physical and genetic mapping of IDDM8 on chromosome 6q27. Diabetes 2000; 49: 508-11.
21. Cox NJ, Wapelhorst B, Morrison VA, et al. Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families. Am J Hum Genet 2001; 69: 820-30. (Pubitemid 32868526)
22. Myerscough A, John S, Barrett JG, et al. Linkage of rheumatoid arthritis to insulin-dependent diabetes mellitus loci: evidence supporting a hypothesis for the existence of common autoimmune susceptibility loci. Arthritis Rheum 2000; 43: 2771-5. (Pubitemid 32001743)
23. Taieb A, Picardo M. VETF members. The definition and assessment of vitiligo: a consensus report of the Vitiligo European Task Force. Pigment Cell Res 2007; 20: 27-35.
24. Rozen S, Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 2000; 132: 365-86.
25. Freeman GH, Halton JH. Note on exact treatment of contingency, goodness of fit and other problems of significance. Biometrika 1951; 38: 141-9.
26. Alzolibani A. Genetic epidemiology and heritability of vitiligo in the Qassim region of Saudi Arabia. Acta Dermatovenerol Alp Panonica Adriat 2009; 18: 119-25.
27. Arýcan O, Koç K, Ersoy L. Clinical characteristics in 113 Turkish vitiligo patients. Acta Dermatovenerol Alp Panonica Adriat 2008; 17: 129-32.
28. Nishimoto S, Hamajima Y, Toda Y, et al. Identification of a novel smooth muscle associated protein, smap2 upregulated during neointima formation in a rat carotid endarterectomy model. Biochim Biophys Acta 2002; 1576: 225-30. (Pubitemid 34597107)
29. Vannahame C, Gosling S, Paulsson M, et al. The definition and assessement of vitiligo: a consensus report of the Vitiligo European Task Force. Pigment Cell Res 2003; 373: 805-14.
30. Krol M, Polanska J, Pawlowski KM, et al. Transcriptomic signature of cell lines isolated from canine mammary adnocarcinoma metastases to lungs. J Appl Genet 2010; 51: 37-50.
31. Liu P, Pazin DE, Merson RR, et al. The developmentally regulated Smoc2 gene is repressed by Aryl-hydrocarbon receptor (Ahr) signaling. Gene 2009; 15: 72-80.
32. Rocnik EF, Liu P, Sato K, et al. The novel SPARK family member SMOC-2 potentiates angiogenic growth factor activity. J Biol Chem 2006; 32: 22855-64.
33. Schallreuter-Wood KU, Pittelkow MR, Swanson NN. Defective calcium transport in vitiliginous melanocytes. Arch Dermatol Res 1996; 288: 11-3.
34. Birlea SA, Fain PR, Spritz RA. A Romanian population isolate with high frequency of vitiligo and associated autoimmune diseases. Arch Dermatol 2008; 144: 310-6.