Functional importance of conserved nucleotides at the histone RNA 3' processing site

RNA

Volumn 4, Issue 3, 1998, Pages 246-256

  Furger, André ^a,b   Schaller, André ^a   Schümperli, Daniel ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b Inst F Allgemeine Mikrobiologie   (Switzerland)

Author keywords

3' end formation; Adenosine; Cleavage site; Mutational analysis; U7 snRNP

Indexed keywords

HISTONE; MESSENGER RNA PRECURSOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE MUTATION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA ANALYSIS; RNA PROCESSING;

ANIMALS; BASE SEQUENCE; BINDING SITES; CONSERVED SEQUENCE; HISTONES; MAMMALS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; VERTEBRATES;

ANIMALIA; VERTEBRATA;

EID: 0031883640     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Birnstiel ML, Schaufele FJ. 1988. Structure and function of minor snRNPs. In: Birnstiel ML, ed. Structure and function of major and minor small nuclear ribonucleoprotein particles. Berlin: Springer Verlag. pp 155-182.
2. Bond UM, Yario TA, Steitz JA. 1991. Multiple processing-defective mutations in mammalian histone premessenger RNA are suppressed by compensatory changes in U7 both in vivo and in vitro. Genes & Dev 5:1709-1722.
3. Chen F, MacDonald CC, Wilusz J. 1995. Cleavage site determinants in the mammalian polyadenylation signal. Nucleic Acids Res 74:2614-2620.
4. Georgiev O, Birnstiel ML. 1985. The conserved CAAGAAAGA spacer sequence is an essential element for the formation of 3′ termini of the sea urchin H3 histone mRNA by RNA processing. EMBO J 4:481-489.
5. Gick O, Krämer A, Keller W, Birnstiel ML. 1986. Generation of histone mRNA 3' ends by endonucleolytic cleavage of the pre-mRNA in a snRNP-dependent in vitro reaction. EMBO J 5:1319-1326.
6. Gick O, Krämer A, Vasserot A, Birnstiel ML. 1987. Heat-labile regulatory factor is required for 3' processing of histone precursor mRNAs. Proc Natl Acad Sci USA 84:8937-8940.
7. Lüscher B, Schümperli D. 1987. RNA 3′ processing regulates histone mRNA levels in a mammalian cell cycle mutant. A processing factor becomes limiting in G1-arrested cells. EMBO J 6:1721-1726.
8. Martin F, Schaller A, Eglite S, Schümperli D, Müller B. 1997. The gene for histone RNA hairpin-binding protein is located on human chromosome 4 and encodes a novel type of RNA-binding protein. EMBO J 16:769-778.
9. Maxam AM, Gilbert W. 1981. Sequencing end labelled DNA with base specific chemical cleavages. Methods Enzymol 65:499-560.
10. Meier VS, Böhni R, Schümperli D. 1989. Nucleotide sequence of two mouse histone H4 genes. Nucleic Acids Res 17:795.
11. Melin L, Soldati D, Mital R, Streit A, Schümperli D. 1992. Biochemical demonstration of complex formation of histone pre-mRNA with U7 small nuclear ribonucleoprotein and hairpin binding factors. EMBO J 11:691-697.
12. Moore CL, Sharp PA. 1985. Accurate cleavage and polyadenylation of exogenous RNA substrate. Cell 41:845-855.
13. Mowry KL, Oh R, Steitz JA. 1989. Each of the conserved sequence elements flanking the cleavage site of mammalian histone pre-mRNAs has a distinct role in the 3′ end processing reaction. Mol Cell Biol 9:3105-3108.
14. Pandey NB, Sun JH, Marzluff WF. 1991. Different complexes are formed on the 3′ end of histone mRNA with nuclear and polysomal proteins. Nucleic Acids Res 19:5653-5659.
15. Pandey NB, Williams AS, Sun J, Brown VD, Bond U, Marzluff WF. 1994. Point mutations in the stem-loop at the 3′ end of mouse histone mRNA reduce expression by reducing the efficiency of 3′ end formation. Mol Cell Biol 14:1709-1720.
16. Peattie DA. 1979. Direct chemical method for sequencing RNA. Proc Natl Acad Sci USA 76:1760-1764.
17. Sambrook J, Fritsch EM, Maniatis T. 1989. Molecular cloning: A laboratory manual, 2nd ed. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
18. Sanger F, Nicklen S, Coulson AR. 1977. DNA sequencing with chain terminating inhibitors. Proc Natl Acad Sci USA 74:5463-5467.
19. Scharl EC, Steitz JA. 1994. The site of 3′ end formation of histone messenger RNA is a fixed distance from the downstream element recognized by the U7 snRNP. EMBO J 13:2532-2440.
20. Schaufele F, Gilmartin GM, Bannwarth W, Birnstiel ML. 1986. Compensatory mutations suggest that base pairing with a small nuclear RNA is required to form the 3′ end of H3 messenger RNA. Nature 323:777-781.
21. Sheets MD, Ogg SC, Wickens MP. 1990. Point mutations in AAUAAA and the poly (A) addition site: Effects on the accuracy and efficiency of cleavage and polyadenylation in vitro. Nucleic Acids Res 18:5799-5805.
22. Soldati D, Schümperli D. 1988. Structural and functional characterization of mouse U7 small nuclear RNA active in 3′ processing of histone pre-mRNA. Mol Cell Biol 8:1518-1524.
23. Spycher C, Streit A, Stefanovic, B, Albrecht, D, Wittop Koning TH, Schümperli D. 1994. 3′ End processing of mouse histone pre-mRNA: Evidence for additional base-pairing between U7 snRNA and the pre-mRNA. Nucleic Acids Res 22:4023-4030.
24. Stauber C, Soldati D, Lüscher B, Schümperli D. 1990. Histone-specific RNA 3′ processing in nuclear extracts from mammalian cells. Methods Enzymol 181:74-89.
25. Stefanovic B, Wittop Koning TH, Schümperli D. 1995. A synthetic histone pre-mRNA-U7 small nuclear RNA chimaera undergoing cis-cleavage in the cytoplasm of Xenopus oocytes. Nucleic Acids Res 23:3152-3160.
26. Steitz TA, Steitz JA. 1993. A general two-metal-ion mechanism for catalytic RNA. Proc Natl Acad Sci USA 90:6498-6502.
27. Streit A, Wittop Koning T, Soldati D, Melin L, Schümperli D. 1993. Variable effects of the conserved RNA hairpin element upon 3′ end processing of histone pre-mRNA in vitro. Nucleic Acids Res 21:1569-1575.
28. Vasserot AP, Schaufele FJ, Birnstiel ML. 1989. Conserved terminal hairpin sequences of histone mRNA precursors are not involved in duplex formation with the U7 RNA but act as a target site for a distinct processing factor. Proc Natl Acad Sci USA 36:4345-4349.
29. Wahle E, Keller W. 1992. The biochemistry of 3′ end cleavage and polyadenylation of messenger RNA precursors. Annu Rev Biochem 61:419-441.
30. Williams AS, Marzluff WF. 1995. The sequence of the stem and flanking sequences at the 3′ end of histone mRNA are critical determinants for the binding of the stem-loop binding protein. Nucleic Acids Res 23:654-662.
31. Wittop Koning TH. 1993. Histone pre-mRNA 3′ processing: A closer look into the molecular mechanism [thesis]. Bern: University of Bern.