Trimethoprim-sulfamethoxazole or clindamycin for community-associated MRSA (CA-MRSA) skin infections

Journal of the American Board of Family Medicine

Volumn 23, Issue 6, 2010, Pages 714-719

  Frei, Christopher R ^a,b   Miller, Monica L ^a,b,c   Lewis II, James S ^a,b,d   Lawson, Kenneth A ^a   Hunter, Jonathan M ^b   Oramasionwu, Christine U ^a,b   Talbert, Robert L ^a,b  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c PURDUE UNIVERSITY   (United States)

^d UNIVERSITY HEALTH SYSTEM   (United States)

Author keywords

CA MRSA; Clindamycin; Methicillin resistant Staphylococcus aureus; Skin infections; Trimethoprim sulfamethoxazole

Indexed keywords

CEFALEXIN; CLINDAMYCIN; COTRIMOXAZOLE; DOXYCYCLINE; VANCOMYCIN;

ADULT; ARTICLE; CLINICAL TRIAL; DIABETIC FOOT; FEMALE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; PRESCRIPTION; SKIN INFECTION; SURGICAL DRAINAGE; SURGICAL INFECTION;

ADULT; ANTI-BACTERIAL AGENTS; CLINDAMYCIN; COHORT STUDIES; COMMUNITY-ACQUIRED INFECTIONS; FEMALE; HUMANS; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); RETROSPECTIVE STUDIES; STAPHYLOCOCCAL SKIN INFECTIONS; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION;

EID: 78649854733     PISSN: 15572625     EISSN: 15587118     Source Type: Journal    
DOI: 10.3122/jabfm.2010.06.090270     Document Type: Article

References (12)

1. Styers D, Sheehan DJ, Hogan P, Sahm DF. Laboratory-based surveillance of current antimicrobial resistance patterns and trends among Staphylococcus aureus: 2005 status in the United States. Ann Clin Microbiol Antimicrob 2006;5:2.
2. Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis 2005;41:1373-406.
3. Ellis MW, Lewis JS 2nd. Treatment approaches for community-acquired methicillin-resistant Staphylococcus aureus infections. Curr Opin Infect Dis 2005;18:496-501.
4. Gorwitz RJ, Jernigan DB, Powers JH, Jernigan JA, Participants in the Centers for Disease Control and Prevention-Convened Experts' Meeting on Management of MRSA in the Community. Strategies for clinical management of MRSA in the community: summary of an experts' meeting convened by the Centers for Disease Control and Prevention. March 2006. Available at: http://www.cdc.gov/ ncidod/dhqp/pdf/ar/CAMRSA-ExpMtgStrategies.pdf. Accessed 31 July 2009.
5. Parchman ML, Munoz A. Risk factors for methicillin-resistant Staphylococcal aureus skin and soft tissue infections presenting in primary care: a South Texas Ambulatory Research Network (STARNet) study. J Am Board Fam Med 2009;22:375-9.
6. Szumowski JD, Cohen DE, Kanaya F, Mayer KH. Treatment and outcomes of infections by methicillin-resistant Staphylococcus aureus at an ambulatory clinic. Antimicrob Agents Chemother 2007;51:423-8.
7. Elwell LP, Wilson HR, Knick VB, Keith BR. In vitro and in vivo efficacy of the combination trimethoprim-sulfamethoxazole against clinical isolates of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 1986;29:1092-4.
8. Close SJ, McBurney CR, Garvin CG, Chen DC, Martin SJ. Trimethoprim-sulfamethoxazole activity and pharmacodynamics against glycopeptide-intermediate Staphylococcus aureus. Pharmacotherapy 2002;22:983-9.
9. Cenizal MJ, Skiest D, Luber S, et al. Prospective randomized trial of empiric therapy with trimethoprim-sulfamethoxazole or doxycycline for outpatient skin and soft tissue infections in an area of high prevalence of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 2007;51:2628-30.
10. Barnes EV 2nd, Dooley DP, Hepburn MJ, Baum SE. Outcomes of community-acquired, methicillin-resistant Staphylococcus aureus, soft tissue infections treated with antibiotics other than vancomycin. Mil Med 2006;171:504-7.
11. Rajendran PM, Young D, Maurer T, et al. Randomized, double-blind, placebo-controlled trial of cephalexin for treatment of uncomplicated skin abscesses in a population at risk for community-acquired methicillin-resistant Staphylococcus aureus infection. Antimicrob Agents Chemother 2007;51:4044-8.
12. Centers for Disease Control and Prevention. MRSA infections. Available at: http://www.cdc.gov/mrsa/index.html. Accessed 24 September 2010.