Weight loss in prepubertal obese children is associated with a decrease in adipocyte fatty-acid-binding protein without changes in lipocalin-2: A 2-year longitudinal study

European Journal of Endocrinology

Volumn 163, Issue 6, 2010, Pages 887-893

  Corripio, Raquel ^a   Gónzalez Clemente, José Miguel ^a   Pérez Sánchez, Jacobo ^a   Näf, Sílvia ^b   Gallart, Lluís ^b,c   Nosàs, Ramon ^a   Vendrell, Joan ^b   Caixàs, Assumpta ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b HOSPITAL UNIVERSITARI JOAN XXIII   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID BINDING PROTEIN 4; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; FABP4 PROTEIN, HUMAN; FATTY ACID BINDING PROTEIN; LIPOCALIN;

AGE; ANTHROPOMETRIC PARAMETERS; ARTICLE; BLOOD PRESSURE; BODY MASS; CASE CONTROL STUDY; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; FOLLOW UP; GENDER; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; LEAN BODY WEIGHT; LIFESTYLE MODIFICATION; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; OBESITY; ORAL GLUCOSE TOLERANCE TEST; OUTPATIENT DEPARTMENT; PREPUBERTY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; SCHOOL CHILD; STATISTICAL ANALYSIS; WEIGHT REDUCTION; ADIPOCYTE; BLOOD; LONGITUDINAL STUDY; METABOLISM; PHYSIOLOGY;

ADIPOCYTES; CASE-CONTROL STUDIES; CHILD; FATTY ACID-BINDING PROTEINS; FEMALE; HUMANS; LIPOCALINS; LONGITUDINAL STUDIES; MALE; OBESITY; WEIGHT LOSS;

EID: 78649853126     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-10-0408     Document Type: Article

References (42)

1. IOTF. WHO Consultation on Obesity. Preventing and Managing the Global Epidemic Geneva: WHO, 1998.
2. Weiss R, Dziura J, Burgert T, Tamborlane W, Taksali S, Yeckel C, Allen K, Lopes M, Savoye M, Morrison J, Sherwin R & Caprio S. Obesity and the metabolic syndrome in children and adolescents. New England Journal of Medicine 2004 350 2362-2374. (doi:10.1056/NEJMoa031049)
3. Whitaker R, Wright J, Pepe M, Seidel K & Dietz W. Predicting obesity in young adulthood from childhood and parental obesity. New England Journal of Medicine 1997 337 869-873. (doi:10.1056/NEJM199709253371301)
4. Reilly JJ, Methven E, McDowell ZC, Hacking B, Alexander D, Stewart L & Kelnar CJ. Health consequences of obesity. Archives of Disease in Childhood 2003 88 748-752. (doi:10.1136/adc.88.9.748)
5. Kershaw E & Flier J. Adipose tissue as an endocrine organ. Journal of Clinical Endocrinology and Metabolism 2004 89 2548-2556. (doi:10.1210/jc.2004- 0395)
6. van Dam R & Hu F. Lipocalins and insulin resistance: etiological role of retinol-binding protein 4 and lipocalin-2? Clinical Chemistry 2007 53 5-7. (doi:10.1373/clinchem.2006.080432)
7. Xu A, Wang Y, Xu J, Stejskal D, Tam S, Zhang J, Wat N, Wong W & Lam K. Adipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome. Clinical Chemistry 2006 52 405-413. (doi:10.1373/clinchem.2005.062463)
8. Tso A, Xu A, Sham P ,Wat N, Wang Y, Fong C, Cheung B, Janus E & Lam K. Serum adipocyte fatty acid binding protein as a new biomarker predicting the development of type 2 diabetes: a 10-year prospective study in a Chinese cohort. Diabetes Care 2007 30 2667-2672. (doi:10.2337/dc07-0413)
9. Rhee E, Lee W, Park C, Oh K, Kim B, Sung K & Kim B. The association of serum adipocyte fatty acid-binding protein with coronary artery disease in Korean adults. European Journal of Endocrinology 2009 160 165-172. (doi:10.1530/EJE-08-0665)
10. Wang Y, Lam KS, Kraegen EW, Sweeney G, Zhang J, Tso AW, Chow WS, Wat NM, Xu JY, Hoo RL & Xu A. Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans. Clinical Chemistry 2007 53 34-41. (doi:10.1373/clinchem.2006.075614) (Pubitemid 46047761)
11. Flo T, Smith K, Sato S, Rodriguez D, Holmes M, Strong R, Akira S & Aderem A. Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature 2004 432 917-921. (doi:10.1038/nature03104)
12. Kuwabara T, Mori K, Mukoyama M, Kasahara M, Yokoi H, Saito Y, Yoshioka T, Ogawa Y, Imamaki H, Kusakabe T, Ebihara K, Omata M, Satoh N, Sugawara A, Barasch J & Nakao K. Urinary neutrophil gelatinase-associated lipocalin levels reflect damage to glomeruli, proximal tubules, and distal nephrons. Kidney International 2009 75 285-294. (doi:10.1038/ki.2008.499)
13. Coe N & Bernlohr D. Physiological properties and functions of intracellular fatty acid-binding proteins. Biochimica et Biophysica Acta 1998 1391 287-306.
14. Fu Y, Luo N, Lopes-Virella M & Garvey W. The adipocyte lipid binding protein (ALBP/aP2) gene facilitates foam cell formation in human THP-1 macrophages. Atherosclerosis 2002 165 259-269. (doi:10.1016/S0021-9150(02)00305- 2)
15. Reinehr T, Stoffel-Wagner B & Roth C. Adipocyte fatty acid-binding protein in obese children before and after weight loss. Metabolism 2007 56 1735-1741. (doi:10.1016/j.metabol.2007.07.019)
16. Khalyfa A, Bhushan B, Hegazi M, Kim J, Kheirandish-Gozal L, Bhattacharjee R, Capdevila O & Gozal D. Fatty-acid binding protein 4 gene variants and childhood obesity: potential implications for insulin sensitivity and CRP levels. Lipids in Health and Disease 2010 15 9-18. (doi:10.1186/1476-511X-9-18)
17. Hernández M CJ, Narvaiza JL, Rincón JM, Ruiz J, Sánchez E & Sobradillo B. Curvas y tablas de crecimiento. Instituto sobre crecimiento y desarrollo. Fundación Orbegozo. Ed Garsi. Madrid, 1988.
18. Marshall W & Tanner J. Variations in pattern of pubertal changes in girls. Archives of Disease in Childhood 1969 44 291-303. (doi:10.1136/adc.44. 235.291)
19. Marshall W & Tanner J. Variations in the pattern of pubertal changes in boys. Archives of Disease in Childhood 1970 45 13-23. (doi:10.1136/adc.45. 239.13)
20. Serra Majem L, Ribas Barba L, Aranceta Bartrina J, Pérez Rodrigo C, Saavedra Santana P & Peña Quintana L. Childhood and adolescent obesity in Spain. Results of the enKid study (1998-2000). Medicina Clínica 2003 121 725-732. (doi:10.1157/13049799)
21. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 2004 114 555-576. (doi:10.1542/peds.114.2.S2.555)
22. Cole T. The LMS method for constructing normalized growth standards. European Journal of Clinical Nutrition 1990 44 45-60. (Pubitemid 20177198)
23. Cole TJ, Bellizzi MC, Flegal KM & Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 2000 320 1240-1243. (doi:10.1136/bmj.320.7244.1240)
24. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2004 27 (Supplement 1) S5-S10. (doi:10.2337/diacare.27. 2007.S5)
25. Matthews D, Hosker J, Rudenski A, Naylor B, Treacher D & Turner R. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985 28 412-419. (doi:10.1007/BF00280883)
26. Reinehr T & Andler W. Changes in the atherogenic risk factor profile according to degree of weight loss. Archives of Disease in Childhood 2004 89 419-422. (doi:10.1136/adc.2003.028803)
27. Stejskal D, Karpísek M, Humenanska V, Hanulova Z, Stejskal P, Kusnierova P & Petzel M. Lipocalin-2: development, analytical characterization, and clinical testing of a new ELISA. Hormone and Metabolic Research 2008 40 381-385. (doi:10.1055/s-2008-1062746)
28. Kanaka-Gantenbein C, Margeli A, Pervanidou P, Sakka S, Mastorakos G, Chrousos GP & Papassotiriou I. Retinol-binding protein 4 and lipocalin-2 in childhood and adolescent obesity: when children are not just "small adults". Clinical Chemistry 2008 54 1176-1182. (doi:10.1373/clinchem.2007. 099002)
29. Liu Q & Nilsen-Hamilton M. Identification of a new acute phase protein. Journal of Biological Chemistry 1995 270 22565-22570. (doi:10.1074/jbc.270.38.22565)
30. Meheus L, Fransen L, Raymackers J, Blockx H, Van Beeumen J, Van Bun S & Van de Voorde A. Identification by microsequencing of lipopolysaccharide- induced proteins secreted by mouse macrophages. Journal of Immunology 1993 151 1535-1547.
31. Lin Y, Rajala M, Berger J, Moller D, Barzilai N & Scherer P. Hyperglycemia-induced production of acute phase reactants in adipose tissue. Journal of Biological Chemistry 2001 276 42077-42083. (doi:10.1074/jbc. M107101200)
32. Zhang J, Wu Y, Zhang Y, Leroith D, Bernlohr DA & Chen X. The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages. Molecular Endocrinology 2008 22 1416-1426. (doi:10.1210/me.2007-0420)
33. Yeung D, Xu A, Cheung C, Wat N, Yau M, Fong C, Chau M & Lam K. Serum adipocyte fatty acid-binding protein levels were independently associated with carotid atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology 2007 27 1796-1802. (doi:10.1161/ATVBAHA.107.146274)
34. Xu A, Tso A, Cheung B, Wang Y, Wat N, Fong C, Yeung D, Janus E, Sham P & Lam K. Circulating adipocyte-fatty acid binding protein levels predict the development of the metabolic syndrome: a 5-year prospective study. Circulation 2007 115 1537-1543. (doi:10.1161/CIRCULATIONAHA.106.647503)
35. Stejskal D & Karpisek M. Adipocyte fatty acid binding protein in a Caucasian population: a new marker of metabolic syndrome? European Journal of Clinical Investigation 2006 36 621-625. (doi:10.1111/j.1365-2362.2006.01696.x)
36. Simón I, Escoté X, Vilarrasa N, Gómez J, Fernández-Real J, Megía A, Gutiérrez C, Gallart L, Masdevall C & Vendrell J. Adipocyte fatty acid-binding protein as a determinant of insulin sensitivity in morbid-obese women. Obesity 2009 17 1124-1128. (doi:10.1038/oby.2008.665)
37. Fisher R, Hoffstedt J, Hotamisligil G, Thörne A & Rydén M. Effects of obesity and weight loss on the expression of proteins involved in fatty acid metabolism in human adipose tissue. International Journal of Obesity and Related Metabolic Disorders 2002 26 1379-1385. (doi:10.1038/sj.ijo.0802110)
38. Lam D, Xu A, Lam K, Lam B, Lam J, Lui M & Ip M. Serum adipocyte-fatty acid binding protein level is elevated in severe OSA and correlates with insulin resistance. European Respiratory Journal 2009 33 346-351. (doi:10.1183/09031936.50075408)
39. Boord J, Maeda K, Makowski L, Babaev V, Fazio S, Linton M & Hotamisligil G. Adipocyte fatty acid-binding protein, aP2, alters late atherosclerotic lesion formation in severe hypercholesterolemia. Arteriosclerosis, Thrombosis, and Vascular Biology 2002 22 1686-1691. (doi:10.1161/01.ATV.0000033090.81345.E6)
40. Makowski L & Hotamisligil G. Fatty acid binding proteins - the evolutionary crossroads of inflammatory and metabolic responses. Journal of Nutrition 2004 134 2464S-2468S.
41. Yun K, Kim S, Choi K & Park H. Association between adipocyte fatty acid-binding protein levels and childhood obesity in Korean children. Metabolism 2009 58 798-802. (doi:10.1016/j.metabol.2009.01.017)
42. Möhlig M, Weickert M, Ghadamgadai E, Machlitt A, Pfüller B, Arafat A, Pfeiffer A & Schöfl C. Adipocyte fatty acid-binding protein is associated with markers of obesity, but is an unlikely link between obesity, insulin resistance, and hyperandrogenism in polycystic ovary syndrome women. European Journal of Endocrinology 2007 157 195-200. (doi:10.1530/EJE-07-0102)