Potentially inappropriate medication for the elderly: Adaptation and evaluation of a French consensus list;Unangemessene arzneistoffe für geriatrische patienten: Anpassung und bewertung einer Französischen konsensusliste

Medizinische Monatsschrift fur Pharmazeuten

Volumn 33, Issue 8, 2010, Pages

  Kölzsch, Marita ^a   Bolbrinker, Juliane ^a   Huber, Matthias ^a   Kreutz, Reinhold ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Appropriateness; Elderly; Inappropriate prescribing; Pharmacotherapy

Indexed keywords

AMITRIPTYLINE; BENZODIAZEPINE; BROMAZEPAM; CHLORDIAZEPOXIDE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CLOBAZAM; CLOMIPRAMINE; CYPROHEPTADINE; DEXCHLORPHENIRAMINE; DIAZEPAM; DOXEPIN; DOXYLAMINE; FLUNITRAZEPAM; FLUPHENAZINE; HYDROXYZINE; IMIPRAMINE; INDOMETACIN; LEVOMEPROMAZINE; MAPROTILINE; MEQUITAZINE; NITRAZEPAM; OXYBUTYNIN; PERPHENAZINE; PHENYLBUTAZONE; PRAZEPAM; PROMETHAZINE; SOLIFENACIN; TOLTERODINE; TRIMIPRAMINE; UNINDEXED DRUG;

AGED; CENTRAL NERVOUS SYSTEM; CONSENSUS; DRUG CLASSIFICATION; DRUG SAFETY; GERMANY; HUMAN; MEDICAL LITERATURE; MEDICATION ERROR; REVIEW; ARTICLE; FRANCE; INAPPROPRIATE PRESCRIBING; STATISTICS;

AGED; CONSENSUS; FRANCE; HUMANS; INAPPROPRIATE PRESCRIBING;

EID: 78649838837     PISSN: 03429601     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (78)

1. Allain H, Bentue-Ferrer D, Tarral A, Gandon JM. Effects on postural oscillation and memory functions of a single dose of zolpidem 5 mg, zopiclone 3.75 mg and lormetazepam 1 mg in elderly healthy subjects. A randomized, cross-over, double-blind study versus placebo. Eur J Clin Pharmacol 2003;59:179-88.
2. Amado-Boccara I, Gougoulis N, Poirier Littre MF, Galinowski A, et al. Effects of antidepressants on cognitive functions: a review. Neurosci Biobehav Rev 1995;19:479-93.
3. American Geriatrics Society. Pharmacological management of persistent pain in older persons. J Am Geriatr Soc 2009;57:1331-46.
4. Ancelin ML, Artero S, Portet F, Dupuy AM, et al. Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: longitudinal cohort study. BMJ 2006;332:455-9.
5. Anon. European Stroke Prevention Study 2. Efficacy and safety data. J Neurol Sci 1997;151(Suppl):1-77.
6. Arzneimittelkommission der deutschen Ärzteschaft. Lungenfibrose nach Nitrofurantoin. Dtsch Arztebl 2007;30:A2149.
7. Beers MH, Ouslander JG. Risk factors in geriatric drug prescribing. A practical guide to avoiding problems. Drugs 1989;37:105-12.
8. Bocksberger JP, Gexfabry M, Gauthey L, Balantgorgia AE. Clomipramine therapy in the geriatric hospital - Experience with therapeutic drug-monitoring. Ther Drug Monit 1994;16:113-9.
9. Brown MJ, Palmer CR, Castaigne A, de Leeuw PW, et al. Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT). Lancet 2000;356:366-72.
10. Bulat T, Castle SC, Rutledge M, Quigley P. Clinical practice algorithms: Medication management to reduce fall risk in the elderly - Part 4, anticoagulants, anticonvulsants, anticholinergics/bladder relaxants, and antipsychotics. J Am Acad Nurse Pract 2008;20:181-90.
11. Chew ML, Mulsant BH, Pollock BG, Lehman ME, et al. Anticholinergic activity of 107 medications commonly used by older adults. J Am Geriatr Soc 2008;56:1333-41.
12. Deutsche Hochdruckliga e.V. DHL® - Deutsche Hypertonie Gesellschaft. AWMF Leitlinie Hypertonie 2008. www.uni-duesseldorf.de/AWMF/ll/046-001.pdf (Zugriff am 29.04.2010).
13. DGPPN, DGN. S3-Leitlinie "Demenzen" 2009. www.uni-duesseldorf. de/AWMF/ll/038-013l.pdf (Zugriff am 29.04.2010).
14. Dixon JS, Mills JG, Ehsanullah RS, Wood JR. Association of age with the efficacy and safety of ranitidine and cimetidine in acute duodenal ulcer disease. Age Ageing 1993;22:411-8.
15. Dujardin K, Guieu JD, Leconte-Lambert C, Leconte P, et al. Comparison of the effects of zolpidem and flunitrazepam on sleep structure and daytime cognitive functions. A study of untreated unsomniacs. Pharmacopsychiatry 1998;31:14-8.
16. Dwyer PL, Teele JS. Prazosin: a neglected cause of genuine stress incontinence. Obstet Gynecol 1992;79:117-21.
17. Fick DM, Cooper JW, Wade WE, Waller JL, et al. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 2003;163:2716-24.
18. Fischer-Barnicol D, Lanquillon S, Haen E, Zofel P, et al. Typical and atypical antipsychotics - The misleading dichotomy. Neuropsychobiology 2008;57:80-7.
19. Fonad E, Emami A, Wahlin TB, Winblad B, et al. Falls in somatic and dementia wards at Community Care Units. Scand J Caring Sci 2009;23:2-10.
20. Fukuuchi Y, Tohgi H, Okudera T, Ikeda Y, et al. A randomized, double-blind study comparing the safety and efficacy of clopidogrel versus ticlopidine in Japanese patients with noncardioembolic cerebral infarction. Cerebrovasc Dis 2008;25:40-9.
21. Goetz CG, Poewe W, Rascol O, Sampaio C. Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004. Mov Disord 2005;20:523-39.
22. Hader C, Gräf-Gruß R. Diabetes mellitus im Alter. Diabetologie 2008:186-90.
23. Hartikainen S, Lonnroos E, Louhivuori K. Medication as a risk factor for falls: critical systematic review. J Gerontol A Biol Sci Med Sci 2007;62:1172-81.
24. Holt S, Schmiedl S, Thürmann P. Development of a german list of potentially inappropriate medication in the elderly. GAA 2009. www.egms.de/static/resources/meetings/gaa2009/GAA2009-Abstractband.pdf (Zugriff am 29.04.2010).
25. Hurdon V, Viola R, Schroder C. How useful is docusate in patients at risk for constipation? A systematic review of the evidence in the chronically ill. J Pain Symptom Manage 2000;19:130-6.
26. Iravani A, Klimberg I, Briefer C, Munera C, et al. A trial comparing low-dose, short-course ciprofloxacin and standard 7 day therapy with co-trimoxazole or nitrofurantoin in the treatment of uncomplicated urinary tract infection. J Antimicrob Chemother 1999;43(Suppl A):67-75.
27. Ivanhoe CB, Francisco GE, McGuire JR, Subramanian T, et al. Intrathecal baclofen management of poststroke spastic hypertonia: implications for function and quality of life. Arch Phys Med Rehabil 2006;87:1509-15.
28. Jano E, Aparasu RR. Healthcare outcomes associated with beers' criteria: a systematic review. Ann Pharmacother 2007;41:438-47.
29. Johnson AG, Quinn DI, Day RO. Non-steroidal anti-inflammatory drugs. Med J Aust 1995;163:155-8.
30. Johnson B, Hoch K, Errichetti A, Johnson J. Effects of methyldopa on psychometric performance. J Clin Pharmacol. 1990;30:1102-5.
31. Kato K, Furuhashi K, Suzuki K, Murase T, et al. Overactive bladder and glaucoma: a survey at outpatient clinics in Japan. Int J Urol 2007;14:595-7.
32. Kay GG, Ebinger U. Preserving cognitive function for patients with overactive bladder: evidence for a differential effect with darifenacin. Int J Clin Pract 2008;62:1792-800.
33. Kienzle-Horn S, Vix JM, Schuijt C, Peil H, et al. Comparison of bisacodyl and sodium picosulphate in the treatment of chronic constipation. Curr Med Res Opin 2007;23:691-9.
34. Kornasoff D, Maisenbacher J, Bowdler J, Raber A. The efficacy and tolerability of aceclofenac compared to indomethacin in patients with rheumatoid arthritis. Rheumatol Int 1996;15:225-30.
35. Kronig B, Pittrow DB, Kirch W, Welzel D, et al. Different concepts in first-line treatment of essential hypertension. Comparison of a low-dose reserpine-thiazide combination with nitrendipine monotherapy. German Reserpine in Hypertension Study Group. Hypertension 1997;29:651-8.
36. Lackner TE, Wyman JF, McCarthy TC, Monigold M, et al. Randomized, placebo-controlled trial of the cognitive effect, safety, and tolerability of oral extended-release oxybutynin in cognitively impaired nursing home residents with urge urinary incontinence. J Am Geriatr Soc 2008;56:862-70.
37. Lahdes K, Kaila T, Huupponen R, Salminen L, et al. Systemic absorption of topically applied ocular atropine. Clin Pharmacol Ther 1988;44:310-4.
38. Laroche ML, Charmes JP, Merle L. Potentially inappropriate medications in the elderly: a French consensus panel list. Eur J Clin Pharmacol 2007;63:725-31.
39. Leipzig RM, Cumming RG, Tinetti ME. Drugs and falls in older people: a systematic review and meta-analysis: I. Psychotropic drugs. J Am Geriatr Soc 1999;47:30-9.
40. Marshall HJ, Beevers DG. Alpha-adrenoceptor blocking drugs and female urinary incontinence: prevalence and reversibility. Br J Clin Pharmacol 1996;42:507-9.
41. Martin U, Hill C, O' Mahony D. Use of moxonidine in elderly patients with resistant hypertension. J Clin Pharm Ther 2005;30:433-7.
42. Materson BJ, Cushman WC, Goldstein G, Reda DJ, et al. Treatment of hypertension in the elderly: I. Blood pressure and clinical changes. Results of a Department of Veterans Affairs Cooperative Study. Hypertension 1990;15:348-60.
43. McCarty-Dawson D, Sue SO, Morrill B, Murdock RH Jr. Ranitidine versus cimetidine in the healing of erosive esophagitis. Clin Ther 1996;18:1150-60.
44. McEvoy JP, McCue M, Spring B, Mohs RC, et al. Effects of amantadine and trihexyphenidyl on memory in elderly normal volunteers. Am J Psychiatry 1987;144:573-7.
45. McLeod PJ, Huang AR, Tamblyn RM, Gayton DC. Defining inappropriate practices in prescribing for elderly people: a national consensus panel. CMAJ. 1997;156:385-91.
46. Modreker MK, Renteln-Kruse W. Medication and falls in old age. Internist 2009;50:493-500.
47. Monroe EW, Bernstein DI, Fox RW, Grabiec SV, et al. Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria. Arzneimittelforschung. 1992;42:1119-21.
48. Nickel JC. Management of urinary tract infections: historical perspective and current strategies: Part 2 - Modern management. J Urol 2005;173:27-32.
49. Novara G, Galfano A, Secco S, D'Elia C, et al. A systematic review and meta-analysis of randomized controlled trials with antimuscarinic drugs for overactive bladder. Eur Urol 2008;54:740-63.
50. Ochs HR, Greenblatt DJ, Friedman H, Burstein ES, et al. Bromazepam pharmacokinetics: influence of age, gender, oral contraceptives, cimetidine, and propranolol. Clin Pharmacol Ther 1987;41:562-70.
51. Olin J, Schneider L, Novit A, Luczak S. Hydergine for dementia. Cochrane Database Syst Rev 2001;CD000359.
52. Pastorello EA, Ortolani C, Gerosa S, Pravettoni V, et al. Antihistaminic treatment of allergic rhinitis: a double-blind study with terfenadine versus dexchlorpheniramine. Pharmatherapeutica 1987;5:69-75.
53. Patanwala AE, Abarca J, Huckleberry Y, Erstad BL. Pharmacologic management of constipation in the critically ill patient. Pharmacotherapy 2006;26:896-902.
54. Prichard BN, Graham BR. I1 imidazoline agonists. General clinical pharmacology of imidazoline receptors: implications for the treatment of the elderly. Drugs Aging 2000;17:133-59.
55. Ramkumar D, Rao SS. Efficacy and safety of traditional medical therapies for chronic constipation: systematic review. Am J Gastroenterol 2005;100:936-71.
56. Rea TD, Siscovick DS, Psaty BM, Pearce RM, et al. Digoxin therapy and the risk of primary cardiac arrest in patients with congestive heart failure: effect of mild-moderate renal impairment. J Clin Epidemiol 2003;56:646-50.
57. Robinson KM, Reinhard SC. Looking ahead in long-term care: the next 50 years. Nurs Clin North Am 2009;44:253-62.
58. Sacco RL, Diener HC, Yusuf S, Cotton D, et al. Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke. N Engl J Med 2008;359:1238-51.
59. Schmidt LG, Degner D, Grohmann R, Kropp S, et al. Severe adverse drug reactions of antidepressants: Results of the German Multicenter Drug Surveillance Program AMSP. Pharmacopsychiatry 2003;36:261.
60. Schwalbe O, Freiberg I, Kloft C. The Beers criteria - an instrument to optimise the pharmacotherapy of geriatric patients. Med Monatsschr Pharm 2007;30:244-8.
61. Shi S, Morike K, Klotz U. The clinical implications of ageing for rational drug therapy. Eur J Clin Pharmacol 2008;64:183-99.
62. Shohrati M, Davoudi SM, Keshavarz S, Sadr B, et al. Cetirizine, doxepine, and hydroxyzine in the treatment of pruritus due to sulfur mustard: a randomized clinical trial. Cutan Ocul Toxicol 2007;26:249-255.
63. Sieber CC. The elderly patient - who is that? Internist 2007;48:1190-2,1194.
64. Simons FE, Fraser TG, Maher J, Pillay N, et al. Central nervous system effects of H1-receptor antagonists in the elderly. Ann Allergy Asthma Immunol 1999;82:157-60.
65. Sink KM, Thomas J, III, Xu H, Craig B, et al. Dual use of bladder anticholinergics and cholinesterase inhibitors: long-term functional and cognitive outcomes. J Am Geriatr Soc 2008;56:847-53.
66. Sopena F, Lanas A. How to advise aspirin use in patients who need NSAIDs. Curr Pharm Des 2007;13:2248-60.
67. Stienstra R, Samhan YM, el Mofty M, de Bont LE, et al. Double-blind comparison of alizapride, droperidol and ondansetron in the treatment of post-operative nausea. Eur J Anaesthesiol 1997;14:290-4.
68. Taniuchi M, Kurz HI, Lasala JM. Randomized comparison of ticlopidine and clopidogrel after intracoronary stent implantation in a broad patient population. Circulation 2001;104:539-43.
69. Taniwa T, Miyataka M, Kimura A, Taniguchi M, et al. Calcium antagonists for secondary prevention of myocardial infarction: is there a need to shift from short-acting to long-acting types? Circ J 2005;69:1308-14.
70. Toornvliet R, van Berckel BN, Luurtsema G, Lubberink M, et al. Effect of age on functional P-glycoprotein in the blood-brain barrier measured by use of (R)-[(11)C]-verapamil and positron emission tomography. Clin Pharmacol Ther 2006;79:540-8.
71. Tune LE. Anticholinergic effects of medication in elderly patients. J Clin Psychiatry 2001;62(Suppl 21):11-4.
72. Wehling M. Drug therapy in the elderly: too much or too little, what to do? A new assessment system: fit for the aged (FORTA). Dtsch Med Wochenschr 2008;133:2289-91.
73. Wehmeier PM, Kluge M, Maras A, Riemann D, et al. Fluoxetine versus trimipramine in the treatment of depression in geriatric patients. Pharmacopsychiatry 2005;38:13-6.
74. Wezenberg E, Verkes RJ, Sabbe BG, Ruigt GS, et al. Modulation of memory and visuospatial processes by biperiden and rivastigmine in elderly healthy subjects. Psychopharmacology. 2005;181:582-94.
75. Wille E, Schrappe M, Gerlach FM, Glaeske G, et al. Koordination und Integration - Gesundheitsversorgung in einer Gesellschaft des längeren Lebens 2009. www.svr-gesundheit.de/Startseite/Startseite.htm (Zugriff am 29.04.2010).
76. Willekens-Bogaers MA, Vollaard EJ. Neuroleptics in psychogeriatrics. A proposal for a more rational prescription policy. Tijdschr Gerontol Geriatr 1985;16:179-89.
77. Wilson K, Mottram P. A comparison of side effects of selective serotonin reuptake inhibitors and tricyclic antidepressants in older depressed patients: a meta-analysis. Int J Geriatr Psychiatry 2004;19:754-62.
78. Woolcott JC, Richardson KJ, Wiens MO, Patel B, et al. Meta-analysis of the impact of 9 medication classes on falls in elderly persons. Arch Intern Med 2009;169:1952-60.