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Volumn 45, Issue 11-12, 2010, Pages 696-706

Disturbances of gastrointestinal motility in intensive care units;Gastrointestinale Motilitätsstörungen auf der Intensivstation Ursachen, Konsequenzen und Therapie

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIA; ARTIFICIAL VENTILATION; EDEMA; ENTERIC FEEDING; GASTROINTESTINAL MOTILITY; HUMAN; INTENSIVE CARE UNIT; INTESTINE FUNCTION; PROPHYLAXIS; REVIEW; SEPSIS;

EID: 78649838306     PISSN: 09392661     EISSN: 14391074     Source Type: Journal    
DOI: 10.1055/s-0030-1268871     Document Type: Review
Times cited : (9)

References (61)
  • 1
    • 78649864782 scopus 로고    scopus 로고
    • Eckert J. Forst H. Buchardi H. (Hrsg) Intensivmedizin Landsberg/Lech Ecomed Verlagsgesellschaft AG & Co.
    • Berger D. Der Darm als Motor des Multiorganversagen. In: Eckert J Forst H Buchardi H (Hrsg) Intensivmedizin. Landsberg/Lech Ecomed Verlagsgesellschaft AG & Co. 2002
    • (2002) Der Darm Als Motor des Multiorganversagen
    • Berger, D.1
  • 2
    • 34047167850 scopus 로고    scopus 로고
    • Comparative study of the intestinal mucus barrier in normal and inflamed colon
    • Swidsinski A, Loening-Baucke V, Theissig F et al. Comparative study of the intestinal mucus barrier in normal and inflamed colon. Gut 2007 56 343-350
    • (2007) Gut , vol.56 , pp. 343-350
    • Swidsinski, A.1    Loening-Baucke, V.2    Theissig, F.3
  • 3
    • 0024370183 scopus 로고
    • Simple intestinal obstruction causes bacterial translocation in man
    • Deitich EA. Simple intestinal obstruction causes bacterial translocation in man. Arch Surg 1983 124 699-701
    • (1983) Arch Surg , vol.124 , pp. 699-701
    • Deitich, E.A.1
  • 4
    • 0026026308 scopus 로고
    • Bacterial translocation from the gut impairs systemic immunity
    • Deitich EA, Xu DZ, Qu L et al. Bacterial translocation from the gut impairs systemic immunity. Surgery 1991 109 269-276
    • (1991) Surgery , vol.109 , pp. 269-276
    • Deitich, E.A.1    Xu, D.Z.2    Qu, L.3
  • 5
    • 0032816821 scopus 로고    scopus 로고
    • Gut origin of sepsis: A prospective study investigating associations between bacterial translocation, gastric microflora and septic morbidity
    • MacFie J, O'Boyle C, Mitchell CJ et al. Gut origin of sepsis: a prospective study investigating associations between bacterial translocation, gastric microflora and septic morbidity. Gut 1999 45 223-228
    • (1999) Gut , vol.45 , pp. 223-228
    • MacFie, J.1    O'Boyle, C.2    Mitchell, C.J.3
  • 6
    • 2342594524 scopus 로고    scopus 로고
    • Opioids and opioid receptors in the enteric nervous system: From a problem in opioid analgesia to a possible new prokinetic therapy in humans
    • Holzer P. Opioids and opioid receptors in the enteric nervous system: from a problem in opioid analgesia to a possible new prokinetic therapy in humans. Neurosci lett 2004 361 192-195
    • (2004) Neurosci Lett , vol.361 , pp. 192-195
    • Holzer, P.1
  • 7
    • 33746463168 scopus 로고    scopus 로고
    • Gastrointestinal failure in intensive care: A retrospective clinical study in three different intensive care units in Germany and Estonia
    • Reintam A, Parm P, Redlich U et al. Gastrointestinal failure in intensive care: a retrospective clinical study in three different intensive care units in Germany and Estonia. BMC Gastroentrology 2006 6 19-19
    • (2006) BMC Gastroentrology , vol.6 , pp. 19-19
    • Reintam, A.1    Parm, P.2    Redlich, U.3
  • 9
    • 0033843311 scopus 로고    scopus 로고
    • Low potential of dobutamine and dopexamine to block intestinal peristalsis as compared with other catecholamines
    • Fruhwald S, Scheidl S, Toller W, Petnehazy T, Holzer P, Metzler H, Hammer HF. Low potential of dobutamine and dopexamine to block intestinal peristalsis as compared with other catecholamines. Crit Care Med 2000 28 2893-2897
    • (2000) Crit Care Med , vol.28 , pp. 2893-2897
    • Fruhwald, S.1    Scheidl, S.2    Toller, W.3    Petnehazy, T.4    Holzer, P.5    Metzler, H.6    Hammer, H.F.7
  • 11
    • 1842476336 scopus 로고    scopus 로고
    • Central and peripheral mechanism by which ghrelin regulates gut motility
    • Peeters TL. Central and peripheral mechanism by which ghrelin regulates gut motility. JJP 2003 54 95-103
    • (2003) JJP , vol.54 , pp. 95-103
    • Peeters, T.L.1
  • 12
    • 0030763641 scopus 로고    scopus 로고
    • Lipopolysaccharide activates the muscularis macrophage network and suppresses circular smooth muscle activity
    • Eskandari MK, Kalff JC, Billiar TR et al. Lipopolysaccharide activates the muscularis macrophage network and suppresses circular smooth muscle activity. Am J Physiology 1997 273 727-734
    • (1997) Am J Physiology , vol.273 , pp. 727-734
    • Eskandari, M.K.1    Kalff, J.C.2    Billiar, T.R.3
  • 13
    • 0036144097 scopus 로고    scopus 로고
    • Pathogenesis of paralytic ileus: Intestinal manipulation opens a transient pathway between the intestinal lumen and the leukocytic infiltrate of the jejunal muscularis
    • Schwarz T, Beer-Stolz D, Simmons R et al. Pathogenesis of paralytic ileus: Intestinal manipulation opens a transient pathway between the intestinal lumen and the leukocytic infiltrate of the jejunal muscularis. Ann Surg 2002 235 31-40
    • (2002) Ann Surg , vol.235 , pp. 31-40
    • Schwarz, T.1    Beer-Stolz, D.2    Simmons, R.3
  • 14
    • 4143089210 scopus 로고    scopus 로고
    • Mechanism of polymicrobial sepsis-induced ileus
    • Ovenhaus M, Tögel S, Pezzone A et al. Mechanism of polymicrobial sepsis-induced ileus. AJP 2004 287
    • (2004) AJP , vol.287
    • Ovenhaus, M.1    Tögel, S.2    Pezzone, A.3
  • 15
    • 3042779069 scopus 로고    scopus 로고
    • Abdomnial compartment syndrome: The cause or effect of postinjury multiple organ failure
    • Balogh Z, Mc Kinley BA, Cox CS Jr et al. Abdomnial compartment syndrome: the cause or effect of postinjury multiple organ failure. Shock 2003 20 483-492
    • (2003) Shock , vol.20 , pp. 483-492
    • Balogh, Z.1    Mc Kinley, B.A.2    Cox, Jr.C.S.3
  • 16
    • 13844292787 scopus 로고    scopus 로고
    • Resuscitation-induced gut edema and intestinal dysfunction
    • Moore-Olufemi S, Xue H, Attuwaybi B et al. Resuscitation-induced gut edema and intestinal dysfunction. J Trauma 2005 58 264-270
    • (2005) J Trauma , vol.58 , pp. 264-270
    • Moore-Olufemi, S.1    Xue, H.2    Attuwaybi, B.3
  • 17
    • 0037172426 scopus 로고    scopus 로고
    • Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: A randomised controlled trial
    • Lobo DN, Bostock KA, Neal KR, Perkins AC, Rowlands BJ, Allison SP. Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: a randomised controlled trial. Lancet 2002 359 1812-1818
    • (2002) Lancet , vol.359 , pp. 1812-1818
    • Lobo, D.N.1    Bostock, K.A.2    Neal, K.R.3    Perkins, A.C.4    Rowlands, B.J.5    Allison, S.P.6
  • 18
    • 43249116657 scopus 로고    scopus 로고
    • - and -adrenergic receptor mechanisms in spontaneous contractile activity of rat ileal longitudinal smooth muscle
    • Seiler R, Rickenbacher BA, Shaw S, Balsiger B. - and -adrenergic receptor mechanisms in spontaneous contractile activity of rat ileal longitudinal smooth muscle. J Gastrointest Surg 2008 12 1087-1093
    • (2008) J Gastrointest Surg , vol.12 , pp. 1087-1093
    • Seiler, R.1    Rickenbacher, B.A.2    Shaw, S.3    Balsiger, B.4
  • 20
    • 52449113457 scopus 로고    scopus 로고
    • Leucocyte and platelet adhesion in different layers of the small bowel during experimental total warm ischemia and reperfusion
    • Beuk RJ, Tangelder GJ, Maassen RL et al. Leucocyte and platelet adhesion in different layers of the small bowel during experimental total warm ischemia and reperfusion. Br J Surg 2008 95 1294-1304
    • (2008) Br J Surg , vol.95 , pp. 1294-1304
    • Beuk, R.J.1    Tangelder, G.J.2    Maassen, R.L.3
  • 21
    • 67349119441 scopus 로고    scopus 로고
    • Opioid receptors in the gastrointestinal tract
    • Holzer P. Opioid receptors in the gastrointestinal tract. Regulatory Peptids 2009 155 11-17
    • (2009) Regulatory Peptids , vol.155 , pp. 11-17
    • Holzer, P.1
  • 22
    • 7944230640 scopus 로고    scopus 로고
    • Function of opioids in the enteric nervous system
    • Wood JD, Galligan JJ. Function of opioids in the enteric nervous system. Neurogastroentrol Motil 2004 16 17-28
    • (2004) Neurogastroentrol Motil , vol.16 , pp. 17-28
    • Wood, J.D.1    Galligan, J.J.2
  • 23
    • 0037249711 scopus 로고    scopus 로고
    • Opioid-induced bowel dysfunction: Pathophysiology and potential new therapies
    • Kurz A, Sessler DI. Opioid-induced bowel dysfunction: pathophysiology and potential new therapies. Drugs 2003 63 649-671
    • (2003) Drugs , vol.63 , pp. 649-671
    • Kurz, A.1    Sessler, D.I.2
  • 25
    • 0036895023 scopus 로고    scopus 로고
    • Clonidine and dexmedetomidine potently inhibit peristalsis in the Guinea pig ileum in vitro
    • Herbert MK, Roth-Goldbrunner S, Holzer P et al. Clonidine and dexmedetomidine potently inhibit peristalsis in the Guinea pig ileum in vitro. Anaesthesiology 2002 97 1491-1499
    • (2002) Anaesthesiology , vol.97 , pp. 1491-1499
    • Herbert, M.K.1    Roth-Goldbrunner, S.2    Holzer, P.3
  • 26
    • 10944261024 scopus 로고    scopus 로고
    • Peristalsis in the Guinea pig small intestine in vitro is impaired by acetaminophen but not aspirin or dipyrone
    • Herbert MK, Weis R, Holzer P et al. Peristalsis in the Guinea pig small intestine in vitro is impaired by acetaminophen but not aspirin or dipyrone. Anasth Analg 2005 100 120-127
    • (2005) Anasth Analg , vol.100 , pp. 120-127
    • Herbert, M.K.1    Weis, R.2    Holzer, P.3
  • 27
    • 30944435036 scopus 로고    scopus 로고
    • Bacterial translocation studied in 927 patients over 13 years
    • MacFie J, Reddy BS, Gatt M et al. Bacterial translocation studied in 927 patients over 13 years. Br J Surg 2006 93 87-93
    • (2006) Br J Surg , vol.93 , pp. 87-93
    • MacFie, J.1    Reddy, B.S.2    Gatt, M.3
  • 28
    • 0029935286 scopus 로고    scopus 로고
    • Role of the gut in multiple organ failure: Bacterial translocation and permeability changes
    • Swank GM, Deitch EA. Role of the gut in multiple organ failure: bacterial translocation and permeability changes. World J Surg 1996 20 411-417
    • (1996) World J Surg , vol.20 , pp. 411-417
    • Swank, G.M.1    Deitch, E.A.2
  • 29
  • 30
    • 77956180069 scopus 로고    scopus 로고
    • Gastric residual volume during enteral nutrition in ICU patients: The REGANE study
    • Montejo JC, Miambres E, Bordejé L et al. Gastric residual volume during enteral nutrition in ICU patients: the REGANE study. Intensive Care Med 2010 36 1386-1393
    • (2010) Intensive Care Med , vol.36 , pp. 1386-1393
    • Montejo, J.C.1    Miambres, E.2    Bordejé, L.3
  • 31
    • 15744372103 scopus 로고    scopus 로고
    • Mechanisms of gastroesophageal reflux in critically ill mechanically ventilated patients
    • Nind G, Chen WH, Protheroe R et al. Mechanisms of gastroesophageal reflux in critically ill mechanically ventilated patients. Gastroenterology 2005 128 600-606
    • (2005) Gastroenterology , vol.128 , pp. 600-606
    • Nind, G.1    Chen, W.H.2    Protheroe, R.3
  • 32
    • 25444520274 scopus 로고    scopus 로고
    • Antro-pyloro-duodenal motor response to gastric and duodenal nutrient in critically ill patients
    • Chapman M, Fraser R, Vozzo R et al. Antro-pyloro-duodenal motor response to gastric and duodenal nutrient in critically ill patients. Gut 2005 54 1384-1390
    • (2005) Gut , vol.54 , pp. 1384-1390
    • Chapman, M.1    Fraser, R.2    Vozzo, R.3
  • 34
    • 4344574496 scopus 로고    scopus 로고
    • Fluid, electrolytes and nutrition: Physiological and clinical aspects
    • Lobo DN. Fluid, electrolytes and nutrition: physiological and clinical aspects. Proc Nutr Soc 2004 63 453-466
    • (2004) Proc Nutr Soc , vol.63 , pp. 453-466
    • Lobo, D.N.1
  • 35
    • 0000529116 scopus 로고    scopus 로고
    • In: Johnson L.R. (Hrsg) Physiology of gastrointestinal tract New York Raven Press
    • Walsh JH. Gastrointestinal hormones. In: Johnson LR (Hrsg) Physiology of gastrointestinal tract. New York Raven Press 181-253
    • Gastrointestinal Hormones , pp. 181-253
    • Walsh, J.H.1
  • 36
    • 67650941315 scopus 로고    scopus 로고
    • Intestinal edema: Effect of enteral feeding on motility and gene expression
    • Moore-Olufemi SD, Padalecki J, Olufemi SE et al. Intestinal edema: Effect of enteral feeding on motility and gene expression. J Surg Res 2009 155 283-292
    • (2009) J Surg Res , vol.155 , pp. 283-292
    • Moore-Olufemi, S.D.1    Padalecki, J.2    Olufemi, S.E.3
  • 37
    • 0024406735 scopus 로고
    • TEN versus TPN following major abdominal trauma Reduced septic morbidity
    • Moore FA et al. TEN versus TPN following major abdominal trauma Reduced septic morbidity. Journal of Trauma 1989 29 916-922
    • (1989) Journal of Trauma , vol.29 , pp. 916-922
    • Moore, F.A.1
  • 38
    • 0042279261 scopus 로고    scopus 로고
    • Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients
    • Heyland DK et al. Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. JPEN 2003 27 355-373
    • (2003) JPEN , vol.27 , pp. 355-373
    • Heyland, D.K.1
  • 39
    • 0032914757 scopus 로고    scopus 로고
    • Early enteral nutritional support improves outcome: Hypothesis or fact?
    • Zaloga GP. Early enteral nutritional support improves outcome: hypothesis or fact? Crit Care Med 1999 27 259-261
    • (1999) Crit Care Med , vol.27 , pp. 259-261
    • Zaloga, G.P.1
  • 40
    • 33748353612 scopus 로고    scopus 로고
    • Future perspectives and research initiatives in fast-track surgery
    • Kehlet H. Future perspectives and research initiatives in fast-track surgery. Langenbecks Arch Surg 2006 391 495-498
    • (2006) Langenbecks Arch Surg , vol.391 , pp. 495-498
    • Kehlet, H.1
  • 41
    • 33746879614 scopus 로고    scopus 로고
    • Influences of enteral nutrition combined with probiotics on gut microflora and barrier function of rats with abdominal infection
    • Shen TY, Qin HL, Gao ZG et al. Influences of enteral nutrition combined with probiotics on gut microflora and barrier function of rats with abdominal infection. World J Gastroentrol 2006 12 4352-4358
    • (2006) World J Gastroentrol , vol.12 , pp. 4352-4358
    • Shen, T.Y.1    Qin, H.L.2    Gao, Z.G.3
  • 42
    • 72049084490 scopus 로고    scopus 로고
    • Emerging role of cyclooxygenase isoforms in the control of gastrointestinal neuromuscular functions
    • Fornai M, Antonioli L et al. Emerging role of cyclooxygenase isoforms in the control of gastrointestinal neuromuscular functions. Pharmacology & Therapeutics 2010 125 62-78
    • (2010) Pharmacology & Therapeutics , vol.125 , pp. 62-78
    • Fornai, M.1    Antonioli, L.2
  • 43
    • 10944261024 scopus 로고    scopus 로고
    • Peristalsis in Guinea pig small intestine in vitro is impaired by acetaminophen but not aspirin and dipyrone
    • Herbert MK, Weis R et al. Peristalsis in Guinea pig small intestine in vitro is impaired by acetaminophen but not aspirin and dipyrone. Anesth Analg 2005 100 120-127
    • (2005) Anesth Analg , vol.100 , pp. 120-127
    • Herbert, M.K.1    Weis, R.2
  • 44
    • 0031979221 scopus 로고    scopus 로고
    • Epidural anesthesia and gastrointestinal motility
    • Steinbrook RA. Epidural anesthesia and gastrointestinal motility. Anesth Analg 1998 86 837-844
    • (1998) Anesth Analg , vol.86 , pp. 837-844
    • Steinbrook, R.A.1
  • 45
    • 14044265675 scopus 로고    scopus 로고
    • Effects of lactulose and polyethylene glycol on colonic transit
    • Fritz E, Hammer HF et al. Effects of lactulose and polyethylene glycol on colonic transit. Aliment Pharmacol Ther 2005 21 259-268
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 259-268
    • Fritz, E.1    Hammer, H.F.2
  • 46
    • 2042511019 scopus 로고    scopus 로고
    • Prospective, randomized, parallel-group trial to evaluate the effects of lactulose and polyethylene glycol-4000 on colonic flora in chronic idiopathic constipation
    • Bouhnik Y, Neut C et al. Prospective, randomized, parallel-group trial to evaluate the effects of lactulose and polyethylene glycol-4000 on colonic flora in chronic idiopathic constipation. Aliment Pharmacol Ther 2004 19 889-899
    • (2004) Aliment Pharmacol Ther , vol.19 , pp. 889-899
    • Bouhnik, Y.1    Neut, C.2
  • 48
    • 71449126721 scopus 로고    scopus 로고
    • Review article: Metoclopramide and tardive dyskinesia
    • Rao AS, Carnilleri M. Review article: metoclopramide and tardive dyskinesia. Aliment Pharmacol Ther 2010 31 11-19
    • (2010) Aliment Pharmacol Ther , vol.31 , pp. 11-19
    • Rao, A.S.1    Carnilleri, M.2
  • 49
    • 72449193680 scopus 로고    scopus 로고
    • Translating 5-HT receptor pharmacology
    • Sanger GJ. Translating 5-HT receptor pharmacology. Neurogastroentrol Motil 2009 21 1235-1238
    • (2009) Neurogastroentrol Motil , vol.21 , pp. 1235-1238
    • Sanger, G.J.1
  • 51
    • 70049101578 scopus 로고    scopus 로고
    • Prucalopride: A new drug for the treatment of chronic constipation
    • Tack J. Prucalopride: a new drug for the treatment of chronic constipation. Expert Rev Gastroentrol Hepatol 2009 3 337-343
    • (2009) Expert Rev Gastroentrol Hepatol , vol.3 , pp. 337-343
    • Tack, J.1
  • 52
    • 77951902634 scopus 로고    scopus 로고
    • Tegaserod and the risk of cardiovascular ischemic events: An observational cohort study
    • Loughlin J, Quinn S, RIvero E et al. Tegaserod and the risk of cardiovascular ischemic events: an observational cohort study. J Cardiovasc Pharmacol Ther 2010 15 151-157
    • (2010) J Cardiovasc Pharmacol Ther , vol.15 , pp. 151-157
    • Loughlin, J.1    Quinn, S.2    Rivero, E.3
  • 53
    • 69949088285 scopus 로고    scopus 로고
    • Lack of association of tegaserod with adverse cardiovascular outcomes in a matched case-control study
    • Anderson JL, May HT, Bair TL, Muhlenstein JB et al. Lack of association of tegaserod with adverse cardiovascular outcomes in a matched case-control study. J Cardiovasc Pharmacol Ther 2009 14 170-175
    • (2009) J Cardiovasc Pharmacol Ther , vol.14 , pp. 170-175
    • Anderson, J.L.1    May, H.T.2    Bair, T.L.3    Muhlenstein, J.B.4
  • 54
    • 0033854173 scopus 로고    scopus 로고
    • Erythromycin improves gastric emptying in critically ill patients intolerant of nasogastric feeding
    • Chapman MJ, Fraser RJ et al. Erythromycin improves gastric emptying in critically ill patients intolerant of nasogastric feeding. Crit Care Medicine 2000 28 2334-2337
    • (2000) Crit Care Medicine , vol.28 , pp. 2334-2337
    • Chapman, M.J.1    Fraser, R.J.2
  • 55
    • 33846289906 scopus 로고    scopus 로고
    • Intestinal motility disturbances in intensive care patients pathogenesis and clinical impact
    • Fruhwald S, Holzer P, Metzler H. Intestinal motility disturbances in intensive care patients pathogenesis and clinical impact. Intensive Care Med 2007 33 36-44
    • (2007) Intensive Care Med , vol.33 , pp. 36-44
    • Fruhwald, S.1    Holzer, P.2    Metzler, H.3
  • 56
    • 0033994476 scopus 로고    scopus 로고
    • Treatment of acute colonic pseudo-obstruction with neostigmine
    • Paran H, Silverberg D et al. Treatment of acute colonic pseudo-obstruction with neostigmine. J Am Coll Surg 2000 190 315-318
    • (2000) J Am Coll Surg , vol.190 , pp. 315-318
    • Paran, H.1    Silverberg, D.2
  • 57
    • 1542671791 scopus 로고    scopus 로고
    • Retrospective study of neostigmine for the treatment of acute colonic pseudo-obstruction
    • Abeyta BJ, Albrecht RM, Schermer CR. Retrospective study of neostigmine for the treatment of acute colonic pseudo-obstruction. Am Surg 2001 67 265-268
    • (2001) Am Surg , vol.67 , pp. 265-268
    • Abeyta, B.J.1    Albrecht, R.M.2    Schermer, C.R.3
  • 58
    • 3242716578 scopus 로고    scopus 로고
    • Differential reversal of drug-induced small bowel paralysis by cerulean and neostigmine
    • Fruhwald S, Herk E, Hammer HF, Holzer P et al. Differential reversal of drug-induced small bowel paralysis by cerulean and neostigmine. Intensiv Care Med 2004 30 1414-1420
    • (2004) Intensiv Care Med , vol.30 , pp. 1414-1420
    • Fruhwald, S.1    Herk, E.2    Hammer, H.F.3    Holzer, P.4
  • 59
    • 33846039160 scopus 로고    scopus 로고
    • Regional differences in the effects of various doses of cerulein upon the small-intestinal migrating motor complex in fasted and non-fasted sheep
    • Romanski KW. Regional differences in the effects of various doses of cerulein upon the small-intestinal migrating motor complex in fasted and non-fasted sheep. J Anim Physiol Anim Nutr 2007 91 29-39
    • (2007) J Anim Physiol Anim Nutr , vol.91 , pp. 29-39
    • Romanski, K.W.1
  • 60
    • 0029971436 scopus 로고    scopus 로고
    • Methylnaltrexone prevents morphine-induced delay in oral-cecal transit time without affecting analgesia: A double-blind randomized placebo-controlled trail
    • Yuan CS, Foss JF et al. Methylnaltrexone prevents morphine-induced delay in oral-cecal transit time without affecting analgesia: a double-blind randomized placebo-controlled trail. Clin Pharmacol Ther 1996 59 469-475
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 469-475
    • Yuan, C.S.1    Foss, J.F.2
  • 61
    • 44349145194 scopus 로고    scopus 로고
    • Methylnaltrexone for opioid-induced constipation in advanced illness
    • Thomas J, Karver S et al. Methylnaltrexone for opioid-induced constipation in advanced illness. N Engl J Med 2008 358 2332-2343.
    • (2008) N Engl J Med , vol.358 , pp. 2332-2343
    • Thomas, J.1    Karver, S.2


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