Clonidine has a paradoxical effect on cyclic arousal and sleep bruxism during NREM sleep

Sleep

Volumn 33, Issue 12, 2010, Pages 1711-1716

  Carra, Maria Clotilde ^a,b   Macaluso, Guido M ^c   Rompré, Pierre H ^a   Huynh, Nelly ^a,b   Parrino, Liborio ^c   Terzano, Mario Giovanni ^c   Lavigne, Gilles J ^a,b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^c UNIVERSITY OF PARMA   (Italy)

Author keywords

Clonidine; Cyclic alternating pattern; Rhythmic masticatory muscle activity; Sleep bruxism

Indexed keywords

CLONIDINE;

ADULT; AROUSAL; ARTICLE; BRUXISM; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; HUMAN; MALE; MASTICATORY MUSCLE; MUSCLE CONTRACTION; NONREM SLEEP; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REM SLEEP;

EID: 78649824026     PISSN: 01618105     EISSN: 15509109     Source Type: Journal    
DOI: 10.1093/sleep/33.12.1711     Document Type: Article

References (64)

1. Miyazaki S, Uchida S, Mukai J, Nishihara K. Clonidine effects on all-night human sleep: opposite action of low- and medium-dose clonidine on human NREM-REM sleep proportion. Psychiatry Clin Neurosci 2004;58:138-44.
2. Gentili A, Godschalk MF, Gheorghiu D, Nelson K, Julius DA, Mulligan T. Effect of clonidine and yohimbine on sleep in healthy men: a double-blind, randomized, controlled trial. Eur J Clin Pharmacol 1996;50:463-5. (Pubitemid 26281064)
3. Spiegel R, DeVos JE. Central effects of guanfacine and clonidine during wakefulness and sleep in healthy subjects. Br J Clin Pharmacol 1980;10 Suppl 1:165S-8S.
4. Huynh N, Lavigne GJ, Lanfranchi PA, Montplaisir JY, de Champlain J. The effect of 2 sympatholytic medications - propranolol and clonidine-on sleep bruxism: experimental randomized controlled studies. Sleep 2006;29:307-16.
5. American Academy of Sleep Medicine. Sleep related bruxism. International classification of sleep disorders, 2nd ed.:Diagnosis and coding manual. Westchester, IL: American Academy of Sleep Medicine; 2005:189-92.
6. De Laat A, Macaluso GM. Sleep bruxism as a motor disorder. Mov Disord 2002;17 Suppl 2:S67-9.
7. Lavigne GJ, Rompre PH, Poirier G, Huard H, Kato T, Montplaisir JY. Rhythmic masticatory muscle activity during sleep in humans. J Dent Res 2001;80:443-8. (Pubitemid 32378949)
8. Sato T, Harada Y. Tooth-grinding during sleep as an arousal reaction. Experientia 1971;27:785-6.
9. Macaluso GM, Guerra P, Di Giovanni G, Boselli M, Parrino L, Terzano MG. Sleep bruxism is a disorder related to periodic arousals during sleep. J Dent Res 1998;77:565-73.
10. Kato T, Rompre P, Montplaisir JY, Sessle BJ, Lavigne GJ. Sleep bruxism: an oromotor activity secondary to micro-arousal. J Dent Res 2001;80:1940-4.
11. Kato T, Montplaisir JY, Guitard F, Sessle BJ, Lund JP, Lavigne GJ. Evidence that experimentally induced sleep bruxism is a consequence of transient arousal. J Dent Res 2003;82:284-8.
12. Lavigne GJ, Huynh N, Kato T, et al. Genesis of sleep bruxism: motor and autonomic-cardiac interactions. Arch Oral Biol 2007;52:381-4. (Pubitemid 46329651)
13. Huynh N, Kato T, Rompre PH, et al. Sleep bruxism is associated to micro-arousals and an increase in cardiac sympathetic activity. J Sleep Res 2006;15:339-46.
14. Khoury S, Rouleau GA, Rompre PH, Mayer P, Montplaisir JY, Lavigne GJ. A significant increase in breathing amplitude precedes sleep bruxism. Chest 2008;134:332-7.
15. Lavigne GJ, Manzini C, Kato T. Sleep bruxism. In: Kryger MH, Roth T, Dement WC, eds. Principles and practice of sleep medicine. 4th ed. Philadelphia: Saunders, 2005:946-59.
16. Halasz P, Terzano M, Parrino L, Bodizs R. The nature of arousal in sleep. J Sleep Res 2004;13:1-23.
17. Terzano MG, Parrino L. Origin and significance of the cyclic alternating pattern (CAP). Sleep Med Rev 2000;4:101-23.
18. Parrino L, Smerieri A, Rossi M, Terzano MG. Relationship of slow and rapid EEG components of CAP to ASDA arousals in normal sleep. Sleep 2001;24:881-5.
19. Terzano MG, Parrino L. Clinical applications of cyclic alternating pattern. Physiol Behav 1993;54:807-13. (Pubitemid 23275769)
20. Smerieri A, Parrino L, Agosti M, Ferri R, Terzano MG. Cyclic alternating pattern sequences and non-cyclic alternating pattern periods in human sleep. Clin Neurophysiol 2007;118:2305-13.
21. Terzano MG, Parrino L, Rosa A, Palomba V, Smerieri A. CAP and arousals in the structural development of sleep: an integrative perspective. Sleep Med 2002;3:221-9.
22. Lavigne GJ, Rompre PH, Montplaisir JY. Sleep bruxism: validity of clinical research diagnostic criteria in a controlled polysomnographic study. J Dent Res 1996;75:546-52.
23. Keranen A, Nykanen S, Taskinen J. Pharmacokinetics and side-effects of clonidine. Eur J Clin Pharmacol 1978;13:97-101.
24. Iber C, Ancoli-Israel S, Chesson A, Quan SF. The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications. Westchester, IL: American Academy of Sleep Medicine, 2007:37.
25. Rechtschaffen A, Kales A, eds. A manual of standardized terminology, technique and scoring system for sleep stages of human subjects. Los Angeles: Brain Information Service / Brain Research Institute, 1968.
26. Terzano MG, Parrino L, Sherieri A, et al. Atlas, rules, and recording techniques for the scoring of cyclic alternating pattern (CAP) in human sleep. Sleep Med 2001;2:537-53.
27. Gaudreau H, Joncas S, Zadra A, Montplaisir J. Dynamics of slow-wave activity during the NREM sleep of sleepwalkers and control subjects. Sleep 2000;23:755-60.
28. Achermann P, Dijk DJ, Brunner DP, Borbely AA. A model of human sleep homeostasis based on EEG slow-wave activity: quantitative comparison of data and simulations. Brain Res Bull 1993;31:97-113.
29. Saper CB, Chou TC, Scammell TE. The sleep switch: hypothalamic control of sleep and wakefulness. Trends Neurosci 2001;24:726-31.
30. Carra MC, Macaluso GM, Huynh N, et al. NREM/REM Cyclic fluctuation of sleep arousal is blunted by clonidine. Sleep 2009;32:abstract # 0941.
31. Terzano MG, Parrino L, Smerieri A, et al. CAP and arousals are involved in the homeostatic and ultradian sleep processes. J Sleep Res 2005;14:359-68.
32. Boberly AA, Achermann P. Sleep homeostasis and models of sleep regulation. In: Kryger MH, Roth T, Dement WC, eds. Principles and practices of sleep medicine. 4th ed. Philadelphia: Elsevier Saunders; 2005;4:405-17.
33. Zucconi M, Oldani A, Ferini-Strambi L, Smirne S. Arousal fluctuations in non-rapid eye movement parasomnias: the role of cyclic alternating pattern as a measure of sleep instability. J Clin Neurophysiol 1995;12:147-54.
34. Terzano MG, Monge-Strauss MF, Mikol F, Spaggiari MC, Parrino L. Cyclic alternating pattern as a provocative factor in nocturnal paroxysmal dystonia. Epilepsia 1997;38:1015-25. (Pubitemid 27382940)
35. Terzano MG, Parrino L, Garofalo PG, Durisotti C, Filati-Roso C. Activation of partial seizures with motor signs during cyclic alternating pattern in human sleep. Epilepsy Res 1991;10:166-73.
36. Sforza E, Montagna P, Rinaldi R, et al. Paroxysmal periodic motor attacks during sleep: clinical and polygraphic features. Electroencephalogr Clin Neurophysiol 1993;86:161-6.
37. Parrino L, Boselli M, Buccino GP, Spaggiari MC, Di Giovanni G, Terzano MG. The cyclic alternating pattern plays a gate-control on periodic limb movements during non-rapid eye movement sleep. J Clin Neurophysiol 1996;13:314-23.
38. Fornai F, Blandizzi C, del Tacca M. Central alpha-2 adrenoceptors regulate central and peripheral functions. Pharmacol Res 1990;22:541-54.
39. Szabo B. Imidazoline antihypertensive drugs: a critical review on their mechanism of action. Pharmacol Ther 2002;93:1-35.
40. Grenhoff J, Svensson TH. Clonidine regularizes substantia nigra dopamine cell firing. Life Sci 1988;42:2003-9.
41. Autret A, Minz M, Beillevaire T, Cathala HP, Schmitt H. Effect of clonidine on sleep patterns in man. Eur J Clin Pharmacol 1977;12:319-22.
42. Morilak DA, Jacobs BL. Noradrenergic modulation of sensorimotor processes in intact rats: the masseteric reflex as a model system. J Neurosci 1985;5:1300-6.
43. Katakura N, Chandler SH. Iontophoretic analysis of the pharmacologic mechanisms responsible for initiation and modulation of trigeminal motoneuronal discharge evoked by intra-oral afferent stimulation. Brain Res 1991;549:66-77.
44. De Sarro GB, Ascioti C, Froio F, Libri V, Nistico G. Evidence that locus coeruleus is the site where clonidine and drugs acting at alpha 1- and alpha 2-adrenoceptors affect sleep and arousal mechanisms. Br J Pharmacol 1987;90:675-85. (Pubitemid 17099401)
45. Gaillard JM. Biochemical pharmacology of paradoxical sleep. Br J Clin Pharmacol 1983;16 Suppl 2:205S-30S.
46. Pal D, Mallick BN. Neural mechanism of rapid eye movement sleep generation with reference to REM-OFF neurons in locus coeruleus. Indian J Med Res 2007;125:721-39.
47. Crochet S, Sakai K. Alpha-2 adrenoceptor mediated paradoxical (REM) sleep inhibition in the cat. Neuroreport 1999;10:2199-204.
48. Tononi G, Pompeiano M, Cirelli C. Suppression of desynchronized sleep through microinjection of the alpha 2-adrenergic agonist clonidine in the dorsal pontine tegmentum of the cat. Pflugers Arch 1991;418:512-8.
49. Moroni F, Tanganelli S, Antonelli T, Carla V, Bianchi C, Beani L. Modulation of cortical acetylcholine and gamma-aminobutyric acid release in freely moving guinea pigs: effects of clonidine and other adrenergic drugs. J Pharmacol Exp Ther 1983;227:435-40.
50. Tsurusaki M, Yoshida M, Akasu T, Nagatsu I. Alpha 2-adrenoceptors mediate the inhibition of cholinergic transmission in parasympathetic ganglia of the rabbit urinary bladder. Synapse 1990;5:233-40.
51. Rasch B, Pommer J, Diekelmann S, Born J. Pharmacological REM sleep suppression paradoxically improves rather than impairs skill memory. Nat Neurosci 2009;12:396-7.
52. Roehrs T, Hyde M, Blaisdell B, Greenwald M, Roth T. Sleep loss and REM sleep loss are hyperalgesic. Sleep 2006;29:145-51.
53. Nielsen T, Paquette T, Solomonova E, Lara-Carrasco J, Colombo R, Lanfranchi P. Changes in cardiac variability after REM sleep deprivation in recurrent nightmares. Sleep;33:113-22.
54. Marthol H, Reich S, Jacke J, Lechner KH, Wichmann M, Hilz MJ. Enhanced sympathetic cardiac modulation in bruxism patients. Clin Auton Res 2006;16:276-80.
55. Seraidarian P, Seraidarian PI, das Neves Cavalcanti B, Marchini L, Claro Neves AC. Urinary levels of catecholamines among individuals with and without sleep bruxism. Sleep Breath 2009;13:85-8.
56. Ohayon MM, Li KK, Guilleminault C. Risk factors for sleep bruxism in the general population. Chest 2001;119:53-61.
57. Vanderas AP, Menenakou M, Kouimtzis T, Papagiannoulis L. Urinary catecholamine levels and bruxism in children. J Oral Rehabil 1999;26:103-10.
58. Dauvilliers Y, Maret S, Tafti M. Genetics of normal and pathological sleep in humans. Sleep Med Rev 2005;9:91-100.
59. Hublin C, Kaprio J, Partinen M, Koskenvu M. Parasomnias: co-occurrence and genetics. Psychiatr Genet 2001;11:65-70.
60. Lavigne GJ, Kato T, Kolta A, Sessle BJ. Neurobiological mechanisms involved in sleep bruxism. Crit Rev Oral Biol Med 2003;14:30-46.
61. Grenhoff J, Svensson TH. Clonidine modulates dopamine cell firing in rat ventral tegmental area. Eur J Pharmacol 1989;165:11-8.
62. Morrow BA, George TP, Roth RH. Noradrenergic alpha-2 agonists have anxiolytic-like actions on stress-related behavior and mesoprefrontal dopamine biochemistry. Brain Res 2004;1027:173-8.
63. Magee KR. Bruxisma related to levodopa therapy. JAMA 1970;214:147.
64. Winocur E, Gavish A, Voikovitch M, Emodi-Perlman A, Eli I. Drugs and bruxism: a critical review. J Orofac Pain 2003;17:99-111.