Evaluation of the antidiabetic and antilipaemic activities of the hydroalcoholic extract of phoenix dactylifera palm leaves and its fractions in alloxan-induced diabetic rats

Malaysian Journal of Medical Sciences

Volumn 17, Issue 4, 2010, Pages 4-13

  Mard, Seyyed Ali ^a   Jalalvand, Kowthar ^a   Jafarinejad, Masoumeh ^a   Balochi, Hoda ^a   Naseri, Mohammad Kazem Gharib ^a  

^a AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Antidiabetics; Antilipaemics; Antioxidants; Diabetes mellitus; Plant extracts

Indexed keywords

ALKALOID DERIVATIVE; CHOLESTEROL; FLAVONOID; GLIBENCLAMIDE; GLUCOSE; INSULIN; PHOENIX DACTYLIFERA EXTRACT; PLANT EXTRACT; SAPONIN DERIVATIVE; STEROID; TANNIN DERIVATIVE; TERPENOID DERIVATIVE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ANTILIPEMIC ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; DRUG ACTIVITY; DRUG DOSE COMPARISON; DRUG ISOLATION; FLUID INTAKE; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; MALE; MEDICINAL PLANT; NONHUMAN; PALM TREE; PLANT LEAF; RAT; TOXICITY TESTING; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 78649798090     PISSN: 1394195X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Luo Q, Cai Y, Sun M, Corke H. Hypoglycemic and hypolipidemic effects and antioxidant activity of fruit extracts from Lycium barbarum. Life Sci. 2004;76(2):137-149.
2. Alarcon-Aguilar FJ, Jimenez-Estrada M, Reyes-Chilpa R, Roman-Ramos R. Hypoglycemic effect of extracts and fractions from Psacalium decompositum in healthy and alloxan-diabetic mice. J Ethnopharmacol. 2000;72(1-2):21-27.
3. Gaamoussi F, Israili ZH, Lyoussi B. Hypoglycemic and hypolipidemic effects of an aqueous extract of Chamaerops humilis leaves in obese, hyperglycemic and hyperlipidemic Meriones shawi rats. Pak J Pharm. Sci. 2010;23(2):212-219.
4. Pérez GS, Pérez GRM, Pérez GC, Zavala SMA, Vargas SR. Coyolosa, a new hypoglycemic from Acrocomia mexicana. Pharm Acta Helv. 1997;72(2):105-111.
5. Haines AH. Evidence on the structure of coyolosa. Synthesis of 6,6'-ether linked hexoses. Tetrahedron Lett. 2004;45(4):835-837.
6. Andrade-Cetto A, Heinrich M. Mexican plants with hypoglycaemic effect used in the treatment of diabetes. J Ethnopharmacol. 2005;99(3):325-348.
7. Budin SB, Othman F, Louis SR, Bakar MA, Das S, Mohamed J. The effects of palm oil tocotrienol-rich fraction supplementation on biochemical parameters, oxidative stress and the vascular wall of streptozotocininduced diabetic rats. Clinics. 2009;64(3):235-244.
8. Mokhtari M, Sharifi A, Sabzevari A. Effect of palm seed alcoholic extract on the blood glucose and lipids concentration in male diabetic rats. Sci J Kurdistan Univ Med Sci. 2008;12(4):8-15.
9. Razaghi-azar M, Noori N, Afsharian K. Effect of date on blood sugar in patients with type 1 diabetes mellitus. Iran J Diabetes Lipids Disord. 2005;4(3):27-34.
10. Ranilla LG, Kwon YI, Genovese MI, Lajolo FM, Shetty K. Antidiabetes and antihypertension potential of commonly consumed carbohydrate sweeteners using in vitro models. J Med Food. 2008;11(2):337-348.
11. Aryangat AV, Gerich JE. Type 2 diabetes: Postprandial hyperglycemia and increased cardiovascular risk. Vasc Health Risk Manag. 2010;6:145-155.
12. Sosnowska J, Balslev H. American palm ethnomedicine: A meta-analysis. J Ethnobiol Ethnomed. 2009;5:43.
13. Gilani AH, Khan AU, Ali T, Ajmal S. Mechanisms underlying the antispasmodic and bronchodilatory properties of Terminalia bellerica fruit. J Ethnopharmacol. 2008;116(3):528-538
14. Sofowora A. Screening Plants for Bioactive Agents. In: Medicinal Plants and Traditional Medicinal in Africa. Spectrum Books Ltd, editors. 2nd ed. Ibadan, Nigeria: Sunshine House; 1993. p. 134-156.
15. Trease GE, Evans WC. Pharmacognosy. 15th ed. London: Saunders Publishers; 2002.
16. El-Demerdash FM, Yousef MI, El-Naga NI. Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats. Food Chem Toxicol. 2005;43(1):57-63.
17. Orhan N, Aslan M, Orhan DD, Ergun F, Yeşilada E. In-vivo assessment of antidiabetic and antioxidant activities of grapevine leaves (Vitis vinifera) in diabetic rats. J Ethnopharmacol. 2006;108(2):280-286
18. Venkateswaran S, Pari L. Effect of Coccinia indica on blood glucose, insulin and hepatic key enzymes in experimental diabetes. Pharm Biol. 2002;40(3):165-170.
19. Latha M, Pari L. Antihyperglycaemic effect of Cassia auriculata in experimental diabetes and its effects on key metabolic enzymes involved in carbohydrate metabolism. Clin Exp Pharmacol Physiol. 2003;30(1-2):38-43.
20. Jackson JE, Bressler R. Clinical pharmacology of sulphonylurea hypoglycemic agents: Part 1. Drugs 1981;22(3):211-245.
21. Jurgoński A, Juśkiewicz J, Zduńczyk Z. Ingestion of black chokeberry fruit extract leads to intestinal and systemic changes in a rat model of prediabetes and hyperlipidemia. Plant Foods Hum Nutr. 2008;63(4):176-182.
22. Rauter AP, Martins A, Lopes R, Ferreira J, Serralheiro LM, Araújo ME, et al. Bioactivity studies and chemical profile of the antidiabetic plant Genista tenera. J Ethnopharmacol. 2009;122(2):384-393.
23. Wang HX, Ng TB. Natural products with hypoglycemic, hypotensive, hypocholesteromic, antiatherosclerotic and antithrombotic activities. Life Sci. 1999;65(25):2663-2677.
24. Riyad MA, Abdul Ghani Abdul-Salam S, Suleiman MS. Effect of fenugreek and lupin seeds on the development of experimental diabetes rats. Planta Med. 1998;54(4):286-290.
25. Yokogoshi H, Oda H. Dietary taurine enhances cholesterol degradation and reduces serum and liver cholesterol concentrations in rats fed a high cholesterol-diet. Amino Acids. 2002;23(4):433-439.
26. Chen W, Matuda K, Nishimura N, Yokogoshi H. The effect of taurine on cholesterol degradation in mice fed a high-cholesterol diet. Life Sci. 2004;74(15):1889-1898.
27. Al-Shamaony L, Al-Khazraji SM, Twaij HA. Hypoglycaemic effect of Artemisia herba alba. II. Effect of a valuable extract on some blood parameters in diabetic animals. J Ethnopharmacol. 1994;43(3):167-171.
28. Pari L, Venkateswaran S. Protective role of Phaseolus vulgaris on changes in the fatty acid composition in experimental diabetes. J Med Food. 2004;7(2):204-209.
29. Ahmed I, Lakhani MS, Gillett M, John A, Raza H. Hypotriglyceridemic and hypocholesterolemic effects of anti-diabetic Momordica charantia (karela) fruit extract in streptozotocin-induced diabetic rats. Diabetes Res Clin Pract. 2001;51(3):155-161.
30. Sharma SR, Dwivedi SK, Swarup D. Hypoglycaemic, antihyperglycaemic and hypolipidemic activities of Caesalpinia bonducella seeds in rats. J Ethnopharmacol. 1997;58(1):39-44.
31. Pupim LB, Heimbürger O, Qureshi AR, Ikizler TA, Stenvinkel P. Accelerated lean body mass loss in incident chronic dialysis patients with diabetes mellitus. Kidney Int. 2005;68(5):2368-2374.
32. Kamalakkannan N, Prince PS: Antihyperglycaemic and antioxidant effect of rutin, a polyphenolic flavonoid, in streptozotocin-induced diabetic wistar rats. Basic Clin Pharmacol Toxicol. 2006;98(1):97-103.
33. Hakim ZS, Patel BK, Goyal RK. Effect of chronic ramipril treatment in streptozotocin-induced diabetic rats. Indian J Physiol Pharmacol.1997;41(4):353-360.
34. Rajkumar L, Srinivasan N, Balasubramanian K, Govindarajulu P. Increased degradation of dermal collagen in diabetic rats. Indian J Exp Biol. 1991;29(11):1081-1083.
35. Nagarajan NS, Murugesh N, Thirupathy Kumaresan P, Radha N, Murali A. Antidiabetic and antihyperlipemic effects of Clemeo felina. Fitoterapia. 2005;76(3-4):310-315.
36. Pari L, Saravanan R. Antidiabetic effect of diasulin, an herbal drug, on blood glucose, plasma insulin and hepatic enzymes of glucose metabolism in hyperglycaemic rats. Diabetes Obes Metab. 2004;6(4):286-292.
37. Onat A, Sari I, Yazici M, Can G, Hergenc G, Avci GS. Plasma triglycerides, an independent predictor of cardiovascular disease in men: A prospective study based on a population with prevalent metabolic syndrome. Int J Cardiol. 2006;108:89-95.
38. Lee KT, Sohn IC, Kim DH, Choi JW, Kwon SH, Park HJ. Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozocininduced diabetic rat and their antioxidant activity in vitro. Arch Parm Res. 2000;23(5):461-466.