Novel hexahydrocannabinol analogs as potential anti-cancer agents inhibit cell proliferation and tumor angiogenesis

European Journal of Pharmacology

Volumn 650, Issue 1, 2011, Pages 64-71

  Thapa, Dinesh ^a   Lee, Jong Suk ^a   Heo, Se Woong ^a   Lee, Yong Rok ^a   Kang, Keon Wook ^b   Kwak, Mi Kyoung ^a   Choi, Han Gon ^a   Kim, Jung Ae ^a  

^a Yeungnam University   (South Korea)

^b Chosun University   (South Korea)

Author keywords

Anti angiogenesis; Cell proliferation; NF B; Synthetic hexahydrocannabinol; Tamoxifen resistant MCF 7 breast cancer

Indexed keywords

1 [1 HYDROXY 6,6,9 TRIMETHYL 6A,7,8,9,10,10A HEXAHYDRO 6H BENZO[C]CHROMEN 2 YL]ETHANONE; 3,6,6,9 TETRAMETHYL 6A,7,8,9,10,10A HEXAHYDRO 6H BENZO[C]CHROMEN 1 OL; ANTINEOPLASTIC AGENT; CANNABINOID RECEPTOR; CANNABINOL DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN MCF 7; CHICK; CHORIOALLANTOIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; EMBRYO; ENDOTHELIUM CELL; GENETIC TRANSCRIPTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VIVO STUDY; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; TUMOR VASCULARIZATION; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CANNABINOL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHORIOALLANTOIC MEMBRANE; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 78649745811     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.09.073     Document Type: Article

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