메뉴 건너뛰기




Volumn 96, Issue 1, 2000, Pages 182-187

Heparin-induced thrombocytopenia: New evidence for the dynamic binding of purified anti-PF4-heparin antibodies to platelets and the resultant platelet activation

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR; HEPARIN; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G ANTIBODY; IODINE 125; MONOCLONAL ANTIBODY; THROMBOCYTE FACTOR 4;

EID: 0034235911     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.1.182.013k18_182_187     Document Type: Article
Times cited : (183)

References (27)
  • 1
    • 0028923741 scopus 로고
    • Heparin-induced thrombocytopenia
    • Chong BH. Heparin-induced thrombocytopenia. Br J Haematol. 1995;89:431-439.
    • (1995) Br J Haematol , vol.89 , pp. 431-439
    • Chong, B.H.1
  • 4
    • 0019801715 scopus 로고
    • Heparin-induced thrombocytopenia, effect of heparin platelet antibody on platelets
    • Chong BH, Grace CS, Rozenberg MC. Heparin-induced thrombocytopenia, effect of heparin platelet antibody on platelets. Br J Haematol. 1981;49:531-540.
    • (1981) Br J Haematol , vol.49 , pp. 531-540
    • Chong, B.H.1    Grace, C.S.2    Rozenberg, M.C.3
  • 5
    • 0028854433 scopus 로고
    • Antibodies to macromolecular platelet factor 4-heparin complexes in heparin-induced thrombocytopenia: A study of 44 cases
    • Amiral J, Bridey F, Wolf M, et al. Antibodies to macromolecular platelet factor 4-heparin complexes in heparin-induced thrombocytopenia: a study of 44 cases. Thromb Haemost. 1995;73:21-28.
    • (1995) Thromb Haemost , vol.73 , pp. 21-28
    • Amiral, J.1    Bridey, F.2    Wolf, M.3
  • 6
    • 0028335456 scopus 로고
    • Laboratory diagnosis of heparin-associated thrombocytopenia and comparison of platelet aggregation test, heparin-induced platelet activation test, and platelet factor 4/heparin enzyme-linked immunosorbent assay
    • Greinacher A, Amiral J, Dummel V, Vissac A, Kiefel V, Mueller-Eckhardt C. Laboratory diagnosis of heparin-associated thrombocytopenia and comparison of platelet aggregation test, heparin-induced platelet activation test, and platelet factor 4/heparin enzyme-linked immunosorbent assay. Transfusion. 1994;34:381-385.
    • (1994) Transfusion , vol.34 , pp. 381-385
    • Greinacher, A.1    Amiral, J.2    Dummel, V.3    Vissac, A.4    Kiefel, V.5    Mueller-Eckhardt, C.6
  • 7
    • 0031850163 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: IgG binding to PF4-heparin complexes in the fluid phase and cross-reactivity with low molecular weight heparin and heparinoid
    • Newman PM, Swanson RL, Chong BH. Heparin-induced thrombocytopenia: IgG binding to PF4-heparin complexes in the fluid phase and cross-reactivity with low molecular weight heparin and heparinoid. Thromb Haemost. 1998;80:292-297.
    • (1998) Thromb Haemost , vol.80 , pp. 292-297
    • Newman, P.M.1    Swanson, R.L.2    Chong, B.H.3
  • 8
    • 0030917932 scopus 로고    scopus 로고
    • Heparin-induced platelet aggregation vs platelet factor 4 enzyme-linked immunosorbent assay in the diagnosis of heparin-induced thrombocytopenia-thrombosis
    • Look KA, Sahud M, Flaherty S, Zehnder JL. Heparin-induced platelet aggregation vs platelet factor 4 enzyme-linked immunosorbent assay in the diagnosis of heparin-induced thrombocytopenia-thrombosis. Am J Clin Pathol. 1997;108:78-82.
    • (1997) Am J Clin Pathol , vol.108 , pp. 78-82
    • Look, K.A.1    Sahud, M.2    Flaherty, S.3    Zehnder, J.L.4
  • 9
    • 0029022130 scopus 로고
    • Comparison between platelet factor 4/heparin complexes ELISA and platelet aggregation test in heparin-induced thrombocytopenia
    • Nguyen P, Droulle C, Potron G. Comparison between platelet factor 4/heparin complexes ELISA and platelet aggregation test in heparin-induced thrombocytopenia. Thromb Haemost. 1995;74: 804-805.
    • (1995) Thromb Haemost , vol.74 , pp. 804-805
    • Nguyen, P.1    Droulle, C.2    Potron, G.3
  • 10
    • 0028009642 scopus 로고
    • Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells
    • Visentin GP, Ford SE, Scott JP, Aster RH. Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells. J Clin Invest. 1994;93:81-88.
    • (1994) J Clin Invest , vol.93 , pp. 81-88
    • Visentin, G.P.1    Ford, S.E.2    Scott, J.P.3    Aster, R.H.4
  • 11
    • 0028914288 scopus 로고
    • Antigen generation in heparin-associated thrombocytopenia: The nonimmunologic type and the immunologic type are closely linked in their pathogenesis
    • Greinacher A. Antigen generation in heparin-associated thrombocytopenia: the nonimmunologic type and the immunologic type are closely linked in their pathogenesis. Semin Thromb Hemost. 1995;21:106-116.
    • (1995) Semin Thromb Hemost , vol.21 , pp. 106-116
    • Greinacher, A.1
  • 12
    • 0031038152 scopus 로고    scopus 로고
    • Laboratory investigation of immune thrombocytopenia
    • Warner M, Kelton JG. Laboratory investigation of immune thrombocytopenia. J Clin Pathol. 1997; 50:5-12.
    • (1997) J Clin Pathol , vol.50 , pp. 5-12
    • Warner, M.1    Kelton, J.G.2
  • 13
    • 0030136628 scopus 로고    scopus 로고
    • Platelet binding of IgG from patients with heparin-induced thrombocytopenia
    • Horne MK III, Alkins BR. Platelet binding of IgG from patients with heparin-induced thrombocytopenia. J Lab Clin Med. 1996;127:435-442.
    • (1996) J Lab Clin Med , vol.127 , pp. 435-442
    • Horne M.K. III1    Alkins, B.R.2
  • 14
    • 0027169166 scopus 로고
    • Heparin-associated thrombocytopenia: Immune complexes are attached to the platelet membrane by the negative charge of highly sulfated oligosaccharides
    • Greinacher A, Michels I, Liebenhoff U, Presek P, Mueller-Eckhardt C. Heparin-associated thrombocytopenia: immune complexes are attached to the platelet membrane by the negative charge of highly sulfated oligosaccharides. Br J Haematol. 1993;84:711-716.
    • (1993) Br J Haematol , vol.84 , pp. 711-716
    • Greinacher, A.1    Michels, I.2    Liebenhoff, U.3    Presek, P.4    Mueller-Eckhardt, C.5
  • 15
    • 0028243705 scopus 로고
    • Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4
    • Kelton JG, Smith JW, Warkentin TE, Hayward CP, Denomme GA, Horsewood P. Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4. Blood. 1994;83:3232-3239.
    • (1994) Blood , vol.83 , pp. 3232-3239
    • Kelton, J.G.1    Smith, J.W.2    Warkentin, T.E.3    Hayward, C.P.4    Denomme, G.A.5    Horsewood, P.6
  • 16
    • 0030896915 scopus 로고    scopus 로고
    • Diagnosis of heparin-induced thrombocytopenia in the vascular surgery patient
    • Jackson MR, Krishnamurti C, Aylesworth CA, Alving BM. Diagnosis of heparin-induced thrombocytopenia in the vascular surgery patient. Surgery. 1997;121:419-424.
    • (1997) Surgery , vol.121 , pp. 419-424
    • Jackson, M.R.1    Krishnamurti, C.2    Aylesworth, C.A.3    Alving, B.M.4
  • 17
    • 0032728857 scopus 로고    scopus 로고
    • Further characterization of antibody and antigen in heparin-induced thrombocytopenia
    • Newman PM, Chong BH, Further characterization of antibody and antigen in heparin-induced thrombocytopenia. Br J Haematol. 1999;107:303-309.
    • (1999) Br J Haematol , vol.107 , pp. 303-309
    • Newman, P.M.1    Chong, B.H.2
  • 18
    • 0023013587 scopus 로고
    • Problems in separation of small numbers of platelets from unbound ligands
    • George JN. Problems in separation of small numbers of platelets from unbound ligands. Thromb Res. 1986;44:561-564.
    • (1986) Thromb Res , vol.44 , pp. 561-564
    • George, J.N.1
  • 19
    • 0025314886 scopus 로고
    • Filtration of platelet-poor plasma specimens yields platelet-free plasma: Application for batch analysis of beta-thromboglobulin and platelet factor 4
    • Schiebout-Clark RC, Haven MC, Haire WD, Wilson RB, Markin RS. Filtration of platelet-poor plasma specimens yields platelet-free plasma: application for batch analysis of beta-thromboglobulin and platelet factor 4. Am J Clin Pathol. 1990;94:206-210.
    • (1990) Am J Clin Pathol , vol.94 , pp. 206-210
    • Schiebout-Clark, R.C.1    Haven, M.C.2    Haire, W.D.3    Wilson, R.B.4    Markin, R.S.5
  • 20
    • 0028014541 scopus 로고
    • Heparin-associated thrombocytopenia: Isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen
    • Greinacher A, Potzsch B, Amiral J, Dummel V, Eichner A, Mueller-Eckhardt C. Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen. Thromb Haemost. 1994;71:247-251.
    • (1994) Thromb Haemost , vol.71 , pp. 247-251
    • Greinacher, A.1    Potzsch, B.2    Amiral, J.3    Dummel, V.4    Eichner, A.5    Mueller-Eckhardt, C.6
  • 21
    • 0023039992 scopus 로고
    • Weekly clinicopathological exercises: Normal reference values
    • Anonymous. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises: normal reference values. N Engl J Med. 1986;314:39-49.
    • (1986) N Engl J Med , vol.314 , pp. 39-49
  • 22
    • 0020362545 scopus 로고
    • Kinetics of intravenously administered heparin in normal humans
    • de Swart CAM, Nijmeyer B. Roelofs JMM, Sixma JJ. Kinetics of intravenously administered heparin in normal humans. Blood. 1982;60:1251-1258.
    • (1982) Blood , vol.60 , pp. 1251-1258
    • De Swart, C.A.M.1    Nijmeyer, B.2    Roelofs, J.M.M.3    Sixma, J.J.4
  • 24
    • 0030137932 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Understanding improves but questions remain
    • Aster RH. Heparin-induced thrombocytopenia: understanding improves but questions remain. J Lab Clin Med. 1996;127:418-419.
    • (1996) J Lab Clin Med , vol.127 , pp. 418-419
    • Aster, R.H.1
  • 25
    • 0029878458 scopus 로고    scopus 로고
    • Pathogenicity of IgA and/or IgM antibodies to heparin-PF4 complexes in patients with heparin-induced thrombocytopenia
    • Amiral J, Wolf M, Fischer A, Boyer-Neumann C, Vissac A, Meyer D. Pathogenicity of IgA and/or IgM antibodies to heparin-PF4 complexes in patients with heparin-induced thrombocytopenia. Br J Haematol. 1996;92:954-959.
    • (1996) Br J Haematol , vol.92 , pp. 954-959
    • Amiral, J.1    Wolf, M.2    Fischer, A.3    Boyer-Neumann, C.4    Vissac, A.5    Meyer, D.6
  • 26
    • 0024357798 scopus 로고
    • Heparin-induced thrombocytopenia: Mechanism of interaction of the heparin-dependent antibody with platelets
    • Chong BH, Fawaz I, Chesterman CN, Berndt MC. Heparin-induced thrombocytopenia: mechanism of interaction of the heparin-dependent antibody with platelets. Br J Haematol. 1989;73:235-240.
    • (1989) Br J Haematol , vol.73 , pp. 235-240
    • Chong, B.H.1    Fawaz, I.2    Chesterman, C.N.3    Berndt, M.C.4
  • 27
    • 0023710994 scopus 로고
    • Heparin-induced thrombocytopenia: Laboratory studies
    • Kelton JG, Sheridan D, Santos A, et al. Heparin-induced thrombocytopenia: laboratory studies. Blood. 1988;72:925-930.
    • (1988) Blood , vol.72 , pp. 925-930
    • Kelton, J.G.1    Sheridan, D.2    Santos, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.