Thyroid stimulating hormone receptor (TSHR) intron 1 variants are major risk factors for graves' disease in three European caucasian cohorts

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Płoski, Rafał ^a   Brand, Oliver J ^b,c   Jurecka Lubieniecka, Beata ^d   Franaszczyk, Maria ^a   Kula, Dorota ^d   Krajewski, Paweł ^a   Karamat, Muhammad A ^b   Simmonds, Matthew J ^b,c   Franklyn, Jayne A ^b   Gough, Stephen C L ^c   Jarzab, Barbara ^d   Bednarczuk, Tomasz ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d INSTITUTE OF ONCOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

THYROTROPIN RECEPTOR;

ADULT; ARTICLE; CAUCASIAN; COHORT ANALYSIS; CONTROLLED STUDY; DOMINANT INHERITANCE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE PHENOTYPE CORRELATION; GRAVES DISEASE; HAPLOTYPE; HUMAN; INHERITANCE; INTRON; MAJOR CLINICAL STUDY; POLAND; POPULATION BASED CASE CONTROL STUDY; RECESSIVE INHERITANCE; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; UNITED KINGDOM; CASE CONTROL STUDY; ETHNOLOGY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; MALE; STATISTICAL MODEL;

CASE-CONTROL STUDIES; COHORT STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GRAVES DISEASE; GREAT BRITAIN; HAPLOTYPES; HUMANS; INTRONS; LINKAGE DISEQUILIBRIUM; LOGISTIC MODELS; MALE; POLAND; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, THYROTROPIN; RISK FACTORS;

EID: 78649740926     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015512     Document Type: Article

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