Relationship between plasma cells and hepatic stellate cells in autoimmune hepatitis

Pathology Research and Practice

Volumn 206, Issue 12, 2010, Pages 800-804

  Brandão, Daniel F ^a   Ramalho, Fernando S ^a   Martinelli, Ana L C ^a   Zucoloto, Sérgio ^a   Ramalho, Leandra N Z ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Autoimmune hepatitis; Liver fibrosis; Liver stellate cells; Plasma cells

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; GLIAL FIBRILLARY ACIDIC PROTEIN;

ADOLESCENT; ADULT; ARTICLE; AUTOIMMUNE HEPATITIS; CELL POPULATION; CELLULAR DISTRIBUTION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; FEMALE; FIBROGENESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER CELL; LIVER FIBROSIS; MALE; PHENOTYPE; PLASMA CELL; PROTEIN ANALYSIS; PROTEIN FUNCTION; STAINING; STELLATE CELL; UPREGULATION;

ACTINS; ADOLESCENT; ADULT; AUTOANTIBODIES; BIOLOGICAL MARKERS; BIOPSY; CHILD; CHILD, PRESCHOOL; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HEPATIC STELLATE CELLS; HEPATITIS, AUTOIMMUNE; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CIRRHOSIS; MALE; MIDDLE AGED; MUSCLE, SMOOTH; PLASMA CELLS; YOUNG ADULT;

EID: 78649740724     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2010.08.002     Document Type: Article

References (25)

1. Alvarez F., Berg P.A., Bianchi F.B., Bianchi L., Burroughs A.K., Cançado E.L., Chapman R.W., Cooksley W.G., Czaja A.J., Desmet V.J., Donaldson P.T., Eddleston A.L., Fainboim L., Heathcote J., Homberg J.C., Hoofnagle J.H., Kakumu S., Krawitt E.L., Mackay I.R., MacSween R.N., Maddrey W.C., Manns M.P., McFarlane I.G., Meyer zum Büschenfelde K.H., Zeniya M., et al. International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis. J. Hepatol. 1999, 31:929-938.
2. Bach N., Thung S.N., Schaffner F. The histological features of chronic hepatitis C and autoimmune chronic hepatitis: a comparative analysis. Hepatology 1992, 15:572-577.
3. Bedossa P., Poynard T. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Hepatology 1996, 24:289-293.
4. Blaszyk H., Batts K.P. Autoimmune liver disease - a practical histologic approach to diagnosis. Pathol. Case Rev. 1999, 4:117-125.
5. Clouston A.D., Jonsson J.R., Purdie D.M., Macdonald G.A., Pandeya N., Shorthouse C., Powell E.E. Steatosis and chronic hepatitis C: analysis of fibrosis and stellate cell activation. J. Hepatol. 2001, 34:314-320.
6. Czaja A.J. Autoimmune hepatitis. Evolving concepts and treatment strategies. Dig. Dis. Sci. 1995, 40:435-456.
7. Dienes H.P., Drebber U. Pathology of immune-mediated liver injury. Dig. Dis. 2010, 28:57-62.
8. Friedman S.L. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J. Biol. Chem. 2000, 275:2247-2250.
9. Hassan G., Moreno S., Massimi M., Di Biagio P., Stefanini S. Interleukin-1-producing plasma cells in close contact with hepatocytes in patients with chronic active hepatitis. J. Hepatol. 1997, 27:6-17.
10. Hautekeete M.L., Geerts A. The hepatic stellate (Ito) cell: its role in human liver disease. Virchows Arch. 1997, 430:195-207.
11. Maia J.M., Maranhão H.S., Sena L.V., Rocha L.R., Medeiros I.A., Ramos A.M. Hepatic stellate cell activation and hepatic fibrosis in children with type 1 autoimmune hepatitis: an immunohistochemical study of paired liver biopsies before treatment and after clinical remission. Eur. J. Gastroenterol. Hepatol. 2010, 22:264-269.
12. Maher J.J. Interactions between hepatic stellate cells and the immune system. Semin. Liver Dis. 2001, 21:417-426.
13. Malekzadeh R., Mohamadnejad M., Nasseri-Moghaddam S., Rakhshani N., Tavangar S.M., Sohrabpour A.A., Tahaghoghi S. Reversibility of cirrhosis in autoimmune hepatitis. Am. J. Med. 2004, 117:125-129.
14. Marra F. Hepatic stellate cells and the regulation of liver inflammation. J. Hepatol. 1999, 31:1120-1130.
15. Martinelli A.L., Ramalho L.N., Zucoloto S. Hepatic stellate cells in hepatitis C patients: relationship with liver iron deposits and severity of liver disease. J. Gastroenterol. Hepatol. 2004, 19:91-98.
16. McFarlane I.G. Definition and classification of autoimmune hepatitis. Semin. Liver Dis. 2002, 22:317-324.
17. Meyer zum Büschenfelde K.H., Lohse A.W., Manns M., Poralla T. Autoimmunity and liver disease. Hepatology 1990, 12:354-363.
18. Pinzani M., Marra F. Cytokine receptors and signaling in hepatic stellate cells. Semin. Liver Dis. 2001, 21:397-416.
19. Pinzani M., Marra F., Carloni V. Signal transduction in hepatic stellate cells. Liver 1998, 18:2-13.
20. Rosen F.S., Mackay I. The immunology series comes to an end. N. Engl. J. Med. 2001, 345:1343-1344.
21. Schmitt-Gräff A., Krüger S., Bochard F., Gabbiani G., Denk H. Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers. Am. J. Pathol. 1991, 138:1233-1242.
22. Schvarcz R., Glaumann H., Weiland O. Survival and histological resolution of fibrosis in patients with autoimmune chronic active hepatitis. J. Hepatol. 1993, 18:15-23.
23. Verma S., Gunuwan B., Mendler M., Govindrajan S., Redeker A. Factors predicting relapse and poor outcome in type I autoimmune hepatitis: role of cirrhosis development, patterns of transaminases during remission and plasma cell activity in the liver biopsy. Am. J. Gastroenterol. 2004, 99:1510-1516.
24. Waldenström J.L. Blutproteine und Nahrungseiweiss. Deutsch Z. Verdau Stoffwechselk 1950, 15:113-119.
25. Yatsuji S., Hashimoto E., Kaneda H., Taniai M., Tokushige K., Shiratori K. Diagnosing autoimmune hepatitis in nonalcoholic fatty liver disease: is the International Autoimmune Hepatitis Group scoring system useful?. J. Gastroenterol. 2005, 40:1130-1138.