Antagonistic roles of the ERK and p38 MAPK signalling pathways in globin expression, haem biosynthesis and iron uptake

Biochemical Journal

Volumn 432, Issue 1, 2010, Pages 145-151

  Mardini, Louay ^a   Gasiorek, Jadwiga ^a   Derjuga, Anna ^a   Carrière, Lucie ^a   Schranzhofer, Matthias ^a   Paw, Barry H ^b   Ponka, Prem ^a,c   Blank, Volker ^a,c  

^a MCGILL UNIVERSITY   (Canada)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Erythroleukaemia cell; Erythropoiesis; Haemoglobin; Iron; Mitoferrin; Mitogen activated protein kinase (MAPK)

Indexed keywords

ERYTHROLEUKAEMIA CELL; ERYTHROPOIESIS; HAEMOGLOBIN; MITOFERRIN; MITOGEN ACTIVATED PROTEIN KINASE;

BIOCHEMISTRY; BIOSYNTHESIS; ENZYME ACTIVITY; GENES; HEMOGLOBIN; TRANSCRIPTION;

PLANTS (BOTANY);

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 5 AMINOLEVULINATE SYNTHASE 2; CD71 ANTIGEN; GLOBIN; HEME; HEMOGLOBIN; HEMOGLOBIN BETA CHAIN; HEXAMETHYLENEBISACETAMIDE; IRON; MITOCHONDRIAL IRON TRANSPORTER MITOFERRIN 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; UNCLASSIFIED DRUG; UO 126;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENHANCER REGION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ERYTHROID CELL; ERYTHROLEUKEMIA; ERYTHROLEUKEMIA CELL; ERYTHROPOIESIS; GENE ACTIVITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLOBIN GENE; HEME SYNTHESIS; HEMOGLOBIN BLOOD LEVEL; IMMUNOBLOTTING; IRON TRANSPORT; LEUKEMIA CELL; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION;

ACETAMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; BLOTTING, NORTHERN; BUTADIENES; CELL DIFFERENTIATION; CELL LINE, TUMOR; ENZYME INHIBITORS; GENE EXPRESSION; GLOBINS; HEME; HEMOGLOBINS; IMIDAZOLES; IMMUNOBLOTTING; IRON; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NITRILES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES;

EID: 78649729082     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20100541     Document Type: Article

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